Unbound fraction Guides d'étude, Notes de cours & Résumés

NMTCB Exam Questions with Correct Answers O-15 half life - Answer-2 min C-11 half life - Answer-20 min Radiochemical purity - Answer-fraction of the total radioactivity in a source that is present in the desired chemical form bound tc unbound tc hydrolyzed, reduced tc Chemical purity - Answer-fraction of the material in the desired chemical form. sterility - Answer-Absence of viable microorganisms BET and LAL testing - Answer-test for pyrogens True event - Answer-two ann...

O-15 half life - 2 min C-11 half life - 20 min Radiochemical purity - fraction of the total radioactivity in a source that is present in the desired chemical form bound tc unbound tc hydrolyzed, reduced tc Chemical purity - fraction of the material in the desired chemical form. sterility - Absence of viable microorganisms BET and LAL testing - test for pyrogens

Rank speed of absorption: Po, IM, IV - Answer-Po slowest, then IM, IV fastest Describe drug distribution in relation to protein binding - Answer-Protein binding- Most drugs form a compound and bind with plasma proteins. Drug molecules bound to plasma proteins are pharmacologically inactive. Only the free or unbound portions of the drug acts on the cells. Protein binding allows for some of the drug to be stored and others to be released as needed. This gives the constant blood level and decr...

Saturable transport in intestinal mucusa will (increase/decrease) bioavailability decrease If a drug is comparatively insoluble it will (increase/decrease) bioavailability decrease If a drug is saturable during hepatic metabolism on first pass it will (increase/decrease) bioavailability increase If a drug has saturable plasma protein binding it will (increase/decrease) volume of distribution and fraction unbound increase If a drug is actively secreted it will (inc...

NSG 251 Final Exam With Complete Solutions 2024Rank speed of absorption: Po, IM, IV - correct answer-Po slowest, then IM, IV fastest Describe drug distribution in relation to protein binding - correct answer-Protein binding- Most drugs form a compound and bind with plasma proteins. Drug molecules bound to plasma proteins are pharmacologically inactive. Only the free or unbound portions of the drug acts on the cells. Protein binding allows for some of the drug to be stored and others to be rel...

Pharm Module 1: Introduction to Basic Clinical Pharmacology Exam Questions And Answers 2024 Pharmacokinetics Drug absorption, distribution, binding affinity, metabolism, and excretion What body does to drug Pharmacodynamics Interactions within body tissue What drug does to body Pharmacogenetics Variability in drug response/toxicity due to genetic factors Pharmacogenomics Development and use of medications Three Phases of Drug Actions: 1. Pharmaceutical phase Release of drug from d...

Rank speed of absorption: Po, IM, IV Po slowest, then IM, IV fastest Describe drug distribution in relation to protein binding Protein binding- Most drugs form a compound and bind with plasma proteins. Drug molecules bound to plasma proteins are pharmacologically inactive. Only the free or unbound portions of the drug acts on the cells. Protein binding allows for some of the drug to be stored and others to be released as needed. This gives the constant blood level and decreased risk for...

HOSA Pharmacology Latest Update 100% Correct Pure Food and Drug Act (1906) Forbade the manufacture, sale, and transportation of adulterated or mislabeled foods and drugs. Shirley Amendment of 1912 Prevented fraudulent therapeutic claims by drug manufacturers Harrison Act of 1914 Established the word narcotic and required the use of a stamp on narcotic drug containers. Also regulated the importation, manufacture, sale, and use of opium, codeine, and their derivatives Food, Drug, and Cosmetic A...

PCOL 355 E2 Exam Questions with Correct A An inert gas is needed for density measurements. a. True b. False - Answer-true The Compressibility Index and Hausner ratio of a pharmaceutical powder are identical. a. True b. False - Answer-false The bulk density and tapped density of a pharmaceutical powder are identical. a. True b. False - Answer-false The surface area and specific surface area of a pharmaceutical powder are identical. a. True b. False - Answer-false What is the key ...

Katzung & Trevor's Pharmacology: Examination and Board Review INTRODUCTION 1. A 3-year-old is brought to the emergency department having just ingested a large overdose of tolbutamide, an oral antidiabetic drug. Tolbutamide is a weak acid with a pKa of 5.3. It is capable of entering most tissues, including the brain. On physical examination, the heart rate is 100/min, blood pressure 90/50 mm Hg, and respiratory rate 20/min. Which of the following statements about this case of tolb...