PATHOPHYSIOLOGY – FINAL EXAM STUDY GUIDE

PATHOPHYSIOLOGY – FINAL EXAM STUDY GUIDECONSCIOUSNESS • The state of being aware, or perceiving physical facts or mental concepts; a state of general wakefulness and responsiveness to environment; a functioning sensorium. [L. conscio, to know, to be aware of] • totally aware of surrounding activities and incoming stimuli • oriented to time, place, and people • person can respond quickly and appropriately to questions, commands, or events. • Various levels of reduced consciousness may present as o Lethargy o Confusion o Disorientation o memory loss o unresponsiveness to verbal stimuli o difficulty in arousal • Glasgow Coma Scale o Used for assessing LOC • Coma o Most serious level of loss of consciousness o Affected person does not respond to stimuli (pain, or verbal) o Some reflexes may still be present • Deep coma o Loss of all reflexes o Fixed and dilated pupils o Slow and irregular pulse and respirations AROUSAL • Reticular Activating System • determines the degree of arousal or awareness of the cerebral cortex • The pons and medulla influence the brain's awareness of the incoming pain stimuli o PONS – composed of bundles of both afferent (incoming) and efferent (outgoing) fibers o MEDULLA  contains vital control centers that regulate respiratory and cardiovascular function  contains the coordinating centers that govern coughing, swallowing, vomiting VEGETATIVE STATE • Loss of awareness and mental capabilities • Results from diffuse brain damage AMNESIA • Loss of memory CONVULSION • sudden, involuntary movement with loss of awareness, caused by uncontrolled neuronal discharge in the brain. TONIC • In a state of continuous unremitting action; denoting especially a muscular contraction. 2. Invigorating; increasing physical or mental tone or strength. CLONIC/CLONIC STATE/CLONIC SPASM • Relating to or characterized by clonus • Movement marked by repetitive muscle contractions and relaxations in rapid succession. • Alternate involuntary contraction and relaxation of a muscle DYSPHASIA • Difficulty comprehending language or speaking; partial impairment of communicating ability • Less severe form of aphasia • Caused by damage to the brain APHASIA • Inability to comprehend or express language; total loss of communicating ability • Receptive—damage to Wernicke’s area • Expressive—damage to Broca’s area • Mixed, global—damage to both areas or to the fibers and tracts between them PARESIS • Muscle weakness • Mild paralysis OTORRHEA • Leaking of CSF from the ear • Occurs with fractures • Tearing of meninges o Allows CSF to pass out of the subarachnoid space SEIZURES Seizures (look up types of seizures) ● Generalized o Absence seizures (petit mal) ▪ Lapses of awareness lasting only a few seconds ▪ Appear without warning/end abruptly ▪ More common in children ▪ Are frequently so brief, they go undetected o Tonic-clonic (grand mal) ▪ Most common ▪ Begin with stiffening of limbs (tonic phase) ▪ Followed by jerking of the limbs/face (clonic phase) o Myoclonic ▪ Rapid, brief contractions of bodily muscles ▪ Occur at the same time on both sides of body ▪ Usually involve one arm or a foot ▪ “sudden jerk” movements or “clumsiness”