NR507NP Midterm Exam: Advanced Pathophysiology
Complete Questions and Guide Answers
100% Verified Graded A+
1. Which of the following are considered the "first responders" of the innate immune
system?
Answer. Neutrophils
2. Hives (urticaria) are an example of a
Answer. Type I Hypersensitivity Reaction
3. Allergic contact dermatitis is an example of hypersensi-
tivity reaction.
Answer. Type IV
4. Type 2 (Cytotoxic) hypersensitivity reactions are mediated by
Answer. IgG or IgM
5. Anaphylaxis is a hypersensitivity reaction.
Answer. Type I
,6. Which of the following is the underlying pathology for hay fever?
Formation of autoantibodies.
Activation of complement.
Destruction by T-cells.
Mast cell degranulation.
Answer. Mast Cell Degranulation
7. Which of the following assessment findings would be expected in a patient who
presents with urticaria?
Eosinophilia.
Decreased thyroid-stimulation hormone level.
Thrombocytopenia.
Leukopenia.
Answer. Eosinophilia
8. The diagnosis for an individual who presents to the office with sudden swollen lips
and eyes, shortness of breath and throat tightness after a bee sting is
Anaphylaxis.
,Asthma.
Angioedema.
Reactive airway disease.
Answer. Anaphylaxis
9. Damage occurs with ABO incompatibility because
Complement damages RBC membrane causing cell lysis. Mast
cell degranulation.
Autoantibodies specific for thyroid tissue impairs the receptors for TSH. Antigen/Antibody
complexes attack the RBC.
Answer. Complement damages RBC membrane causing cell lysis
10. Which is true about a primary immunodeficiency?
It is the result of a single gene defect. It
appears primarily in older adults.
It is usually inherited.
It is the result of multiple gene defects.
Answer. It is the result of a single gene defect.
, 11. is a predominant cause of secondary immune
deficiencies worldwide.
Answer. Malnutrition
12. An example of a secondary immunodeficiency is
Job Syndrome.
Common Variable Immunodeficiency.
Familial Mediterranean Fever.
Pneumocystis Carinii.
Answer. Pneumocystis Carinii.
13. An example of a primary immunodeficiency is
Sinus Infection.
Human Immunodeficiency virus.
Pneumonia.
Chronic Granulomatous Disease.
Answer. Chronic Granulomatous Disease
14. True or False. Cancer is a secondary immunodeficiency.
Complete Questions and Guide Answers
100% Verified Graded A+
1. Which of the following are considered the "first responders" of the innate immune
system?
Answer. Neutrophils
2. Hives (urticaria) are an example of a
Answer. Type I Hypersensitivity Reaction
3. Allergic contact dermatitis is an example of hypersensi-
tivity reaction.
Answer. Type IV
4. Type 2 (Cytotoxic) hypersensitivity reactions are mediated by
Answer. IgG or IgM
5. Anaphylaxis is a hypersensitivity reaction.
Answer. Type I
,6. Which of the following is the underlying pathology for hay fever?
Formation of autoantibodies.
Activation of complement.
Destruction by T-cells.
Mast cell degranulation.
Answer. Mast Cell Degranulation
7. Which of the following assessment findings would be expected in a patient who
presents with urticaria?
Eosinophilia.
Decreased thyroid-stimulation hormone level.
Thrombocytopenia.
Leukopenia.
Answer. Eosinophilia
8. The diagnosis for an individual who presents to the office with sudden swollen lips
and eyes, shortness of breath and throat tightness after a bee sting is
Anaphylaxis.
,Asthma.
Angioedema.
Reactive airway disease.
Answer. Anaphylaxis
9. Damage occurs with ABO incompatibility because
Complement damages RBC membrane causing cell lysis. Mast
cell degranulation.
Autoantibodies specific for thyroid tissue impairs the receptors for TSH. Antigen/Antibody
complexes attack the RBC.
Answer. Complement damages RBC membrane causing cell lysis
10. Which is true about a primary immunodeficiency?
It is the result of a single gene defect. It
appears primarily in older adults.
It is usually inherited.
It is the result of multiple gene defects.
Answer. It is the result of a single gene defect.
, 11. is a predominant cause of secondary immune
deficiencies worldwide.
Answer. Malnutrition
12. An example of a secondary immunodeficiency is
Job Syndrome.
Common Variable Immunodeficiency.
Familial Mediterranean Fever.
Pneumocystis Carinii.
Answer. Pneumocystis Carinii.
13. An example of a primary immunodeficiency is
Sinus Infection.
Human Immunodeficiency virus.
Pneumonia.
Chronic Granulomatous Disease.
Answer. Chronic Granulomatous Disease
14. True or False. Cancer is a secondary immunodeficiency.
