EGAN’S FUNDAMENTALS OF RESPIRATORY
CARE EXAM STUDY SHEET 2026 PRACTICE
◉ Ritonavir, an anti-retroviral used in the treatment of human
immunodeficiency virus (HIV), inhibits the metabolism of
fluticasone, an inhaled corticosteroid. What do you predict would
happen to the effects of fluticasone if it is taken with ritonavir?
Answer: Increase
◉ The use of rifampin can increase the metabolism of the COPD
drug, roflumilast, leading to decreased effectiveness of roflumilast.
In this case, rifampin is displaying which type of effect?
Agonist
Enzyme-inducing
Antagonist
Enzyme-inhibiting Answer: Enzyme-inducing
◉ Which of the following can affect the therapeutic effect of a
prescribed medication?
Patient adherence
Organ function
All of these are correct.
Drug interactions Answer: All of these are correct
,◉ Which of the following drug properties will lead to increased drug
absorption?
Strong base
Hydrophilic
Weak acid in the unionized form
Large molecule Answer: Weak acid in the unionized form
◉ Which of the following drugs would be considered a receptor
agonist? Albuterol: exerts its effect by acting on the beta-2 receptor
ipratropium: exerts its effect by blocking the activity of acetylcholine
on the muscarinic receptor Flumazenil: blocks the activity of
benzodiazepines on the GABA receptors
Flumazenil
Albuterol
None of these is correct.
Ipratropium Answer: Albuterol
◉ Which of the following is not involved in drug excretion?
Saliva
Gastrointestinal tract
Lungs
Kidneys Answer: Saliva
, ◉ Which of the following is the definition of a therapeutic dose?
Dose of drug needed to obtain the desired effect
Dose at which 50% of test animals will show a desired effect
Dose at which 50% of animals tested will die
The highest effective dose Answer: Dose of drug needed to obtain
the desired effect
◉ Which of the following organs is most commonly responsible for
biotransformation or metabolism?
Liver
Kidneys
Pancreas
Lungs Answer: Liver
◉ Which of the following processes is not involved in the study of
pharmacokinetics?
Absorption
Distribution
Metabolism
Receptor activity Answer: Receptor activity
CARE EXAM STUDY SHEET 2026 PRACTICE
◉ Ritonavir, an anti-retroviral used in the treatment of human
immunodeficiency virus (HIV), inhibits the metabolism of
fluticasone, an inhaled corticosteroid. What do you predict would
happen to the effects of fluticasone if it is taken with ritonavir?
Answer: Increase
◉ The use of rifampin can increase the metabolism of the COPD
drug, roflumilast, leading to decreased effectiveness of roflumilast.
In this case, rifampin is displaying which type of effect?
Agonist
Enzyme-inducing
Antagonist
Enzyme-inhibiting Answer: Enzyme-inducing
◉ Which of the following can affect the therapeutic effect of a
prescribed medication?
Patient adherence
Organ function
All of these are correct.
Drug interactions Answer: All of these are correct
,◉ Which of the following drug properties will lead to increased drug
absorption?
Strong base
Hydrophilic
Weak acid in the unionized form
Large molecule Answer: Weak acid in the unionized form
◉ Which of the following drugs would be considered a receptor
agonist? Albuterol: exerts its effect by acting on the beta-2 receptor
ipratropium: exerts its effect by blocking the activity of acetylcholine
on the muscarinic receptor Flumazenil: blocks the activity of
benzodiazepines on the GABA receptors
Flumazenil
Albuterol
None of these is correct.
Ipratropium Answer: Albuterol
◉ Which of the following is not involved in drug excretion?
Saliva
Gastrointestinal tract
Lungs
Kidneys Answer: Saliva
, ◉ Which of the following is the definition of a therapeutic dose?
Dose of drug needed to obtain the desired effect
Dose at which 50% of test animals will show a desired effect
Dose at which 50% of animals tested will die
The highest effective dose Answer: Dose of drug needed to obtain
the desired effect
◉ Which of the following organs is most commonly responsible for
biotransformation or metabolism?
Liver
Kidneys
Pancreas
Lungs Answer: Liver
◉ Which of the following processes is not involved in the study of
pharmacokinetics?
Absorption
Distribution
Metabolism
Receptor activity Answer: Receptor activity
