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,3. The dnurse dis dteaching da dpatient dwho dwill dbe ddischarged dhome dwith da dprescription dfor dan
enteric- dcoated dtablet. dWhich dstatement dby dthe dpatient d indicates dunderstanding dof dthe
d
d teaching?
a. Idmay dcrush dthe dtablet dand d put dit din dapplesauce dto dimprove dabsorption.
b. I dshould d consume dacidic dfoodsdto denhance dabsorption dof dthis dmedication.
c. I dshould d expect d a ddelay din donset d of dthe ddrugs deffects dafter dtaking dthe dtablet.
d. I dshould dtake dthis dmedication dwith dhigh-fat dfoods dto dimprove dits
daction. dANS: dC
Enteric-coated dtablets dresist ddisintegration din dthe dacidic denvironment dof dthe dstomach dand
d disintegrate dwhen dthey dreach dthe dsmall dintestine. dThere dis dusually dsome ddelay din donset dof dactions
d after dtaking dthese dmedications. dEnteric-coated dtablets dshould dnot dbe dcrushed dor dchewed, dwhich
d would dalter dthe dtime dand dlocation dof dabsorption. dAcidic dfoods dwill dnot denhance dthe dabsorption dof
d the dmedication. dThe dpatient dshould dnot dto deat dhigh-fat dfood dbefore dingesting dan denteric-coated
d tablet, dbecause dhigh-fat dfoods ddecrease dthe dabsorption drate.
DIF: dCOGNITIVE dLEVEL: dApplying d(Application) dREF: ddm d3
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
4. A dpatient dwho dis dnewly ddiagnosed dwith dtype d1 ddiabetes dmellitus dasks dwhy dinsulin dmust dbe
d given dby dsubcutaneous dinjection dinstead dof dbydmouth. dThe dnurse dwilldexplain dthat dthis dis
because
d
a. absorption dis d diminished d bydthe dfirst-pass deffects din dthe dliver.
b. absorption dis dfaster dwhen dinsulin dis dgiven dsubcutaneously.
c. digestive denzymes din dthe dgastrointestinal dtract dprevent dabsorption.
d. the doral dformdis dless dpredictable dwith dmore dadverse deffects.
d ANS: dC
Insulin, dgrowth dhormones, dand dother dprotein-based ddrugs dare ddestroyed din dthe dsmall dintestine dby
d digestive denzymes dand dmust dbe dgiven dparenterally. dBecause dinsulin dis ddestroyed dby ddigestive
d enzymes, dit dwould dnot dmake dit dto dthe dliver dfor dmetabolism dwith da dfirst-pass deffect. dSubcutaneous
d tissue dhas dfewer dblood dvessels, dso dabsorption dis dslower din dsuch dtissue. dInsulin dis dgiven
d subcutaneously dbecause dit dis ddesirable dto dhave dit dabsorb dslowly.
DIF: dCOGNITIVE dLEVEL: dUnderstanding d(Comprehension) dREF: ddm d3
d TOP: dNURSING dPROCESS: dNursing dIntervention: dPatient dTeaching
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
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, 5. The dnurse dis dpreparing dto dadminister dan doral dmedication dthat dis dwater-soluble. dThe
nurse dunderstands dthat dthis ddrug
d
a. must dbe dtaken don dan dempty dstomach.
b. requires dactive dtransport dfordabsorption.
c. should d be dtaken dwith dfatty dfoods.
d. will dreadily ddiffusedinto dthe dgastrointestinal dtract.
d ANS: dB
Water-soluble d drugs drequire da dcarrier d enzyme d or dprotein d to dpass dthrough dthe dGI dmembrane.
DIF: dCOGNITIVE dLEVEL: dUnderstanding d(Comprehension) dREF: ddm d4
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
6. A dnurse dis dpreparing dto dadminister dan doral ddrug dthat dis dbest dabsorbed din dan dacidic
environment. dHow dwill dthe dnurse dgive dthe ddrug?
d
a. On dan dempty dstomach
b. With da dfull dglass d of dwater
c. With dfood
d. With dhigh-fat dfood
d ANS: dC
Food dcan dstimulate dthe dproduction dof dgastric dacid dso dmedications drequiring dan dacidic denvironment
d should dbe dgiven dwith da dmeal. dHigh-fat dfoods dare duseful dfor ddrugs dthat d are dlipid dsoluble.
DIF: dCOGNITIVE dLEVEL: dApplying d(Application) dREF: ddm d4
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
7. The dnurse dis dpreparing dan dinjectable ddrug dand dwants dto dadminister dit dfor drapid dabsorption.
How dwill dthe dnurse dgive dthis dmedication?
d
a. IM dinto dthe ddeltoid d muscle
b. IM dinto dthe dgluteal dmuscle
c. SubQ dinto dabdominal dtissue
d. SubQ dinto dthe dupper darm
d ANS: dA
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,3. The dnurse dis dteaching da dpatient dwho dwill dbe ddischarged dhome dwith da dprescription dfor dan
enteric- dcoated dtablet. dWhich dstatement dby dthe dpatient d indicates dunderstanding dof dthe
d
d teaching?
a. Idmay dcrush dthe dtablet dand d put dit din dapplesauce dto dimprove dabsorption.
b. I dshould d consume dacidic dfoodsdto denhance dabsorption dof dthis dmedication.
c. I dshould d expect d a ddelay din donset d of dthe ddrugs deffects dafter dtaking dthe dtablet.
d. I dshould dtake dthis dmedication dwith dhigh-fat dfoods dto dimprove dits
daction. dANS: dC
Enteric-coated dtablets dresist ddisintegration din dthe dacidic denvironment dof dthe dstomach dand
d disintegrate dwhen dthey dreach dthe dsmall dintestine. dThere dis dusually dsome ddelay din donset dof dactions
d after dtaking dthese dmedications. dEnteric-coated dtablets dshould dnot dbe dcrushed dor dchewed, dwhich
d would dalter dthe dtime dand dlocation dof dabsorption. dAcidic dfoods dwill dnot denhance dthe dabsorption dof
d the dmedication. dThe dpatient dshould dnot dto deat dhigh-fat dfood dbefore dingesting dan denteric-coated
d tablet, dbecause dhigh-fat dfoods ddecrease dthe dabsorption drate.
DIF: dCOGNITIVE dLEVEL: dApplying d(Application) dREF: ddm d3
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
4. A dpatient dwho dis dnewly ddiagnosed dwith dtype d1 ddiabetes dmellitus dasks dwhy dinsulin dmust dbe
d given dby dsubcutaneous dinjection dinstead dof dbydmouth. dThe dnurse dwilldexplain dthat dthis dis
because
d
a. absorption dis d diminished d bydthe dfirst-pass deffects din dthe dliver.
b. absorption dis dfaster dwhen dinsulin dis dgiven dsubcutaneously.
c. digestive denzymes din dthe dgastrointestinal dtract dprevent dabsorption.
d. the doral dformdis dless dpredictable dwith dmore dadverse deffects.
d ANS: dC
Insulin, dgrowth dhormones, dand dother dprotein-based ddrugs dare ddestroyed din dthe dsmall dintestine dby
d digestive denzymes dand dmust dbe dgiven dparenterally. dBecause dinsulin dis ddestroyed dby ddigestive
d enzymes, dit dwould dnot dmake dit dto dthe dliver dfor dmetabolism dwith da dfirst-pass deffect. dSubcutaneous
d tissue dhas dfewer dblood dvessels, dso dabsorption dis dslower din dsuch dtissue. dInsulin dis dgiven
d subcutaneously dbecause dit dis ddesirable dto dhave dit dabsorb dslowly.
DIF: dCOGNITIVE dLEVEL: dUnderstanding d(Comprehension) dREF: ddm d3
d TOP: dNURSING dPROCESS: dNursing dIntervention: dPatient dTeaching
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
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, 5. The dnurse dis dpreparing dto dadminister dan doral dmedication dthat dis dwater-soluble. dThe
nurse dunderstands dthat dthis ddrug
d
a. must dbe dtaken don dan dempty dstomach.
b. requires dactive dtransport dfordabsorption.
c. should d be dtaken dwith dfatty dfoods.
d. will dreadily ddiffusedinto dthe dgastrointestinal dtract.
d ANS: dB
Water-soluble d drugs drequire da dcarrier d enzyme d or dprotein d to dpass dthrough dthe dGI dmembrane.
DIF: dCOGNITIVE dLEVEL: dUnderstanding d(Comprehension) dREF: ddm d4
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
6. A dnurse dis dpreparing dto dadminister dan doral ddrug dthat dis dbest dabsorbed din dan dacidic
environment. dHow dwill dthe dnurse dgive dthe ddrug?
d
a. On dan dempty dstomach
b. With da dfull dglass d of dwater
c. With dfood
d. With dhigh-fat dfood
d ANS: dC
Food dcan dstimulate dthe dproduction dof dgastric dacid dso dmedications drequiring dan dacidic denvironment
d should dbe dgiven dwith da dmeal. dHigh-fat dfoods dare duseful dfor ddrugs dthat d are dlipid dsoluble.
DIF: dCOGNITIVE dLEVEL: dApplying d(Application) dREF: ddm d4
d TOP: dNURSING dPROCESS: dNursing dIntervention
MSC: dNCLEX: dPhysiological dIntegrity: dPharmacological dand dParenteral dTherapies
7. The dnurse dis dpreparing dan dinjectable ddrug dand dwants dto dadminister dit dfor drapid dabsorption.
How dwill dthe dnurse dgive dthis dmedication?
d
a. IM dinto dthe ddeltoid d muscle
b. IM dinto dthe dgluteal dmuscle
c. SubQ dinto dabdominal dtissue
d. SubQ dinto dthe dupper darm
d ANS: dA
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