NURS 3366 Pathophysiology Exam 1 Study
Guide: Genetics, Cellular Adaptations &
Cancer Review for Nursing Students
Description:
Ace your NURS 3366 Pathophysiology Exam 1 with this comprehensive, updated 2026 study
guide. Covers essential topics including human genetics, autosomal and sex-linked disorders,
Down syndrome, sickle cell anemia, polycystic kidney disease, and teratogenic effects.
Master cellular processes like apoptosis, necrosis, ischemia, hyperplasia, metaplasia, and
dysplasia. Review cancer fundamentals: TNM staging, metastasis, angiogenesis, and tumor
types. Includes practice questions with detailed answer explanations, clinical scenarios, and
integrated case studies—perfect for nursing students preparing for pathophysiology exams,
quizzes, or NCLEX review.
Download your free high-yield study guide now and study smarter, not harder!
, NURS 3366 Pathophysiology Exam 1 Review: Genetics, Cellular
Biology, Cancer & Quiz
1. How many total pairs of chromosomes are present in a typical human somatic cell?
a) 22
b) 23
c) 46
d) 48
Answer: b) 23
Explanation: Humans possess 23 pairs of chromosomes, totaling 46 individual chromosomes in
most body cells. This includes 22 pairs of autosomes and 1 pair of sex chromosomes.
2. What term describes an individual possessing two identical alleles for a specific gene, such as
one associated with a dominant trait?
Answer: Homozygous dominant
Explanation: Homozygous dominant refers to a genotype where both alleles for a gene are the
same dominant form (e.g., GG). This individual will express the dominant phenotype.
3. Which of the following conditions is primarily categorized as a multifactorial inheritance
disorder?
a) Down Syndrome
b) Cystic Fibrosis
c) Type 2 Diabetes Mellitus
d) Hemophilia A
Answer: c) Type 2 Diabetes Mellitus
Explanation: Multifactorial disorders result from complex interactions between multiple genetic
variants and environmental/lifestyle factors. Type 2 Diabetes Mellitus, along with coronary
artery disease and hypertension, are classic examples, unlike single-gene disorders.
4. A newborn presents with neurodevelopmental deficits and distinct facial features. The mother
reported alcohol use during pregnancy. Which teratogenic condition is most likely?
Answer: Fetal Alcohol Spectrum Disorder (FASD)
Explanation: Prenatal alcohol exposure is a known teratogen that can disrupt fetal development,
Guide: Genetics, Cellular Adaptations &
Cancer Review for Nursing Students
Description:
Ace your NURS 3366 Pathophysiology Exam 1 with this comprehensive, updated 2026 study
guide. Covers essential topics including human genetics, autosomal and sex-linked disorders,
Down syndrome, sickle cell anemia, polycystic kidney disease, and teratogenic effects.
Master cellular processes like apoptosis, necrosis, ischemia, hyperplasia, metaplasia, and
dysplasia. Review cancer fundamentals: TNM staging, metastasis, angiogenesis, and tumor
types. Includes practice questions with detailed answer explanations, clinical scenarios, and
integrated case studies—perfect for nursing students preparing for pathophysiology exams,
quizzes, or NCLEX review.
Download your free high-yield study guide now and study smarter, not harder!
, NURS 3366 Pathophysiology Exam 1 Review: Genetics, Cellular
Biology, Cancer & Quiz
1. How many total pairs of chromosomes are present in a typical human somatic cell?
a) 22
b) 23
c) 46
d) 48
Answer: b) 23
Explanation: Humans possess 23 pairs of chromosomes, totaling 46 individual chromosomes in
most body cells. This includes 22 pairs of autosomes and 1 pair of sex chromosomes.
2. What term describes an individual possessing two identical alleles for a specific gene, such as
one associated with a dominant trait?
Answer: Homozygous dominant
Explanation: Homozygous dominant refers to a genotype where both alleles for a gene are the
same dominant form (e.g., GG). This individual will express the dominant phenotype.
3. Which of the following conditions is primarily categorized as a multifactorial inheritance
disorder?
a) Down Syndrome
b) Cystic Fibrosis
c) Type 2 Diabetes Mellitus
d) Hemophilia A
Answer: c) Type 2 Diabetes Mellitus
Explanation: Multifactorial disorders result from complex interactions between multiple genetic
variants and environmental/lifestyle factors. Type 2 Diabetes Mellitus, along with coronary
artery disease and hypertension, are classic examples, unlike single-gene disorders.
4. A newborn presents with neurodevelopmental deficits and distinct facial features. The mother
reported alcohol use during pregnancy. Which teratogenic condition is most likely?
Answer: Fetal Alcohol Spectrum Disorder (FASD)
Explanation: Prenatal alcohol exposure is a known teratogen that can disrupt fetal development,
