NUR 651 FINAL STUDY GUIDE EXAM QUESTIONS AND
ANSWERS GRADED A+ LATEST UPDATE.
Clinical judgement in prescribing includes: ANS >> Factoring in the
cost to the patient of the medication prescribed
The route of excretion of a volatile drug will likely be the: ANS >>
lungs
The NP chooses to give cephalexin every 8 hours based on
knowledge of the drugs: ANS >> biological half-life
Phenytoin requires that a trough level be drawn. Peak and
trough levels are done:
,1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and
saturation of receptor sites
4. To determine if a drug is in the therapeutic range ANS >> To
determine if the drug is in the therapeutic range
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 ANS >> Both 1 & 2: induce OR inhibit
metabolism of another drug
The prudent NP would prescribe liquid ibuprofen for a 6-year-old
because: ANS >> The 6-year-old may not be able to swallow pills
,In deciding which drug to prescribe of all multiple drugs used to
treat a condition, the NP chooses drug A because: ANS >> It will
be taken twice daily at home
Your patient asks the difference in drug effects between men
and women. What should the NP know about the differences
between pharmacokinetics of men and women? ANS >>
Percentage of fat differs between genders
Drugs that have a significant first-pass effect: ANS >> Are rapidly
metabolized by the liver and may have little if any desired action
Azithromycin dosing requires the first day’s dosage be twice
those of the other 4 days of the prescription. This is considered a
loading dose. Loading doses: ANS >> Rapidly achieve drug levels in
the therapeutic range
The point in time on the drug concentration curve that indicates
the first sign of a therapeutic effect is the: ANS >> onset of action
Drugs that are receptor agonists may demonstrate what
property? ANS >> Describes the extent of effect (response)
produced by a given drug concentration (dose)
, Shows the relationship between the dosage/concentration and
the effect of the drug concentration
Therapeutic window (range) ANS >> The range of plasma drug
concentration with high probability of therapeutic response
Provides a fixed comparison for drug safety
What is a narrow therapeutic window? ANS >> A drug that has
little difference between therapeutic and toxic doses
Treatment goals in prescribing should be: ANS >> Patient cantered
storage reservoirs: ANS >> Fat and tissue that the drug has been
distributed to
Passive monitoring: ANS >> patient is educated on expected
outcome and instructed to contact provider (expected side
effects)
A potentially life-threatening adverse response to ACE inhibitors
is angioedema. Which statement is true about this adverse
response? ANS >> Swelling of the tongue and hoarseness are the
most common symptoms.
ANSWERS GRADED A+ LATEST UPDATE.
Clinical judgement in prescribing includes: ANS >> Factoring in the
cost to the patient of the medication prescribed
The route of excretion of a volatile drug will likely be the: ANS >>
lungs
The NP chooses to give cephalexin every 8 hours based on
knowledge of the drugs: ANS >> biological half-life
Phenytoin requires that a trough level be drawn. Peak and
trough levels are done:
,1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and
saturation of receptor sites
4. To determine if a drug is in the therapeutic range ANS >> To
determine if the drug is in the therapeutic range
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 ANS >> Both 1 & 2: induce OR inhibit
metabolism of another drug
The prudent NP would prescribe liquid ibuprofen for a 6-year-old
because: ANS >> The 6-year-old may not be able to swallow pills
,In deciding which drug to prescribe of all multiple drugs used to
treat a condition, the NP chooses drug A because: ANS >> It will
be taken twice daily at home
Your patient asks the difference in drug effects between men
and women. What should the NP know about the differences
between pharmacokinetics of men and women? ANS >>
Percentage of fat differs between genders
Drugs that have a significant first-pass effect: ANS >> Are rapidly
metabolized by the liver and may have little if any desired action
Azithromycin dosing requires the first day’s dosage be twice
those of the other 4 days of the prescription. This is considered a
loading dose. Loading doses: ANS >> Rapidly achieve drug levels in
the therapeutic range
The point in time on the drug concentration curve that indicates
the first sign of a therapeutic effect is the: ANS >> onset of action
Drugs that are receptor agonists may demonstrate what
property? ANS >> Describes the extent of effect (response)
produced by a given drug concentration (dose)
, Shows the relationship between the dosage/concentration and
the effect of the drug concentration
Therapeutic window (range) ANS >> The range of plasma drug
concentration with high probability of therapeutic response
Provides a fixed comparison for drug safety
What is a narrow therapeutic window? ANS >> A drug that has
little difference between therapeutic and toxic doses
Treatment goals in prescribing should be: ANS >> Patient cantered
storage reservoirs: ANS >> Fat and tissue that the drug has been
distributed to
Passive monitoring: ANS >> patient is educated on expected
outcome and instructed to contact provider (expected side
effects)
A potentially life-threatening adverse response to ACE inhibitors
is angioedema. Which statement is true about this adverse
response? ANS >> Swelling of the tongue and hoarseness are the
most common symptoms.
