NSC 830 Advanced Pharm; Diabetes Questions With
Complete Solutions
4 F's of Sulfonylureas Correct Answers 1. Fasting glucose
2. Fail in the long-haul
3. Act Funny
4. Get Fat
ADA goal of HgbA1C Correct Answers Less than 7%
(correlates to a glucose of approximately 150)
Alpha-glucosidase inhibitors Adverse effects Correct Answers
flatulence, diarrhea, abdominal pain
Do not use with chronic Bowel disease
Alpha-glucosidase inhibitors Correct Answers Acarbose
(Precose)
Miglitol (Glyset)
Alpha-glucosidase inhibitors MOA Correct Answers Slows
intestinal carbohydrate digestion/absorption
Alpha-glucosidase inhibitors RED FLAG REMINDER Correct
Answers Does not cause hypoglycemia. But if you think
conjunction with other medications, you cannot treat
hypoglycemia with food. You must use glucose. Such as glucose
tablets
Amylin Agonist Correct Answers Pramlintide (Symlin) SQ
Amylin Agonist drawbacks Correct Answers Administered SQ
, Must be coadministered with insulin
Cannot be mixed = more shots!
TID before meals to decrease postprandial blood sugars.
Amylin Agonist MOA Correct Answers Endogenous peptide.
Cosecreted with insulin by beta cells in response to food.
Slow G.I. emptying
Suppress glucagon secretion
Appetite suppressant/increase satiety
Amylin Agonists Cautions and adverse effects Correct Answers
Adverse effects = G.I. nausea and vomiting
Does not cause hypoglycemia but in conjunction with insulin
high risk for hypoglycemia.
Do not use with gastroparesis do to it slows G.I. motility.
BIGUANIDES Correct Answers Metformin (Glucophage)
DPP-4 inhibitors Adverse effects Correct Answers Minimal!
(GI, HA, URI)
DPP-4 inhibitors Correct Answers The GLIPTINS!
Linagliptin, saxagliptin, sitagliptin
ALL ORAL AGENTS!!
DPP-4 inhibitors MOA Correct Answers Block DPP-4 from
destroying the GLP-1
GLP - 1 (What is it?) Correct Answers Incretin hormone
Glucagon like peptide
Natural peptide from small intestine after eating
Complete Solutions
4 F's of Sulfonylureas Correct Answers 1. Fasting glucose
2. Fail in the long-haul
3. Act Funny
4. Get Fat
ADA goal of HgbA1C Correct Answers Less than 7%
(correlates to a glucose of approximately 150)
Alpha-glucosidase inhibitors Adverse effects Correct Answers
flatulence, diarrhea, abdominal pain
Do not use with chronic Bowel disease
Alpha-glucosidase inhibitors Correct Answers Acarbose
(Precose)
Miglitol (Glyset)
Alpha-glucosidase inhibitors MOA Correct Answers Slows
intestinal carbohydrate digestion/absorption
Alpha-glucosidase inhibitors RED FLAG REMINDER Correct
Answers Does not cause hypoglycemia. But if you think
conjunction with other medications, you cannot treat
hypoglycemia with food. You must use glucose. Such as glucose
tablets
Amylin Agonist Correct Answers Pramlintide (Symlin) SQ
Amylin Agonist drawbacks Correct Answers Administered SQ
, Must be coadministered with insulin
Cannot be mixed = more shots!
TID before meals to decrease postprandial blood sugars.
Amylin Agonist MOA Correct Answers Endogenous peptide.
Cosecreted with insulin by beta cells in response to food.
Slow G.I. emptying
Suppress glucagon secretion
Appetite suppressant/increase satiety
Amylin Agonists Cautions and adverse effects Correct Answers
Adverse effects = G.I. nausea and vomiting
Does not cause hypoglycemia but in conjunction with insulin
high risk for hypoglycemia.
Do not use with gastroparesis do to it slows G.I. motility.
BIGUANIDES Correct Answers Metformin (Glucophage)
DPP-4 inhibitors Adverse effects Correct Answers Minimal!
(GI, HA, URI)
DPP-4 inhibitors Correct Answers The GLIPTINS!
Linagliptin, saxagliptin, sitagliptin
ALL ORAL AGENTS!!
DPP-4 inhibitors MOA Correct Answers Block DPP-4 from
destroying the GLP-1
GLP - 1 (What is it?) Correct Answers Incretin hormone
Glucagon like peptide
Natural peptide from small intestine after eating
