NSG 830 EXAM 1 QUESTIONS & ANSWERS
What medication stains teeth under 8 years old? - Answer -tetracyclines
Who would you not give tetracyclines to? - Answer -Pregnant, nursing, kids under 8
What do you avoid while giving Tetracycles? - Answer -antacids, calcium, milk products
For TB give: - Answer -drug combo
TB treatment requires - Answer -directly observed therapy
Avoid ____ and _____ with TB treatments - Answer -alcohol, tylenol
What would you give a patient taking TB meds for peripheral neuropathy? - Answer -
vitamin b6
Flagyl: No alcohol ____ hours before use, during, or ____ hours after use - Answer -24,
36
Sulfonamides Adverse Effects: photosensitivity, blood dyscrasias, ________ - Answer -
crystalluria
Aminoglycosides AE: _______, nephrotoxicity, ______- - Answer -ototoxicity,
neurotoxicity
What Fluoroquinolone do you give for anrthax? - Answer -Cipro
Cipro can cause _______ and EKG changes with cardiac meds - Answer -tendon
rupture
Rifampin decreases effectiveness of - Answer -oral contraceptives
What med causes C. Diff the most? - Answer -clindamycin
Vancomycin AE: ______ and nephrotoxicity - Answer -ototoxicity
What drugs treat C. Diff>? - Answer -flagyl and vanco
What would you administer with Amphocetarin B? - Answer -antihistamine and
antipyretic
, Antibiotics associated with crystalluria: ________, ______, triamterene - Answer -
sulfonamides, acyclovir
What meds cause photosensitivity? - Answer -tetracyclines, sulfonamides
P450 enzymes are a large class of enzyme systems that metabolize drugs in the _____.
When a patient is taking several drugs metabolized by these systems, drug _____ may
be a problem - Answer -liver, interactions
The time it takes for half of a drug in the body to be eliminated - Answer -half life
______ is a measure of affinity. Affinity refers to the strength of attraction between a
receptor and a drug molecule. - Answer -potency
Drugs with high affinity are more ____ and because these drugs bind effectively at
lower concentrations, _____ doses are needed - Answer -potent, lower
_______ is the ability to produce a desired effect. It is a measure of intrinsic activity.
Drugs with high intrinsic activity have high ______. - Answer -efficacy, efficacy
Drugs that elevate gastric pH will increase ionization of ______ drugs so that they are
not absorbed as easily while decreasing ionization of ______ drugs thus increasing their
absorption. - Answer -acidic, basic
Drugs that decrease peristalsis (antidiarrheals, opioids) can ______ absorption of drugs
given enterally while drugs that promote gastric emptying (prokinetics) and peristalsis
(laxatives) may ______ absorption - Answer -increase, decrease
When drugs compete for limited protein binding sites, the end result will be an ____ in
free (unbound) drug. Only free drug can leave the systemic circulation for distribution;
therefore there will be an increased distribution which can result in a relative over-dose
and possible toxicity - Answer -increase
A drug that is acted upon by an enzyme - Answer -substrate
G6PD is an enzyme that ______ the risk of RBC hemolysis when they are exposed to
oxidizing drugs. When those with G6PD deficiency take drugs such as sulfonamides,
aspirin, and antimalarials they may experience RBC hemolysis, which may be life
threatening. - Answer -reduces
Pregnancy rating scale to identify the risk that taking a drug has on the fetus: A- studies
show no risk. B- There is no evidence of human risk. C- Risk cannot be ruled out. D-
_____ evidence of risk. ___- contraindicated in pregnancy - Answer -positive, X
Drugs that are weak acids are best absorbed in an ______ environment such as gastric
acid because they remain in an nonionized form - Answer -acidic
What medication stains teeth under 8 years old? - Answer -tetracyclines
Who would you not give tetracyclines to? - Answer -Pregnant, nursing, kids under 8
What do you avoid while giving Tetracycles? - Answer -antacids, calcium, milk products
For TB give: - Answer -drug combo
TB treatment requires - Answer -directly observed therapy
Avoid ____ and _____ with TB treatments - Answer -alcohol, tylenol
What would you give a patient taking TB meds for peripheral neuropathy? - Answer -
vitamin b6
Flagyl: No alcohol ____ hours before use, during, or ____ hours after use - Answer -24,
36
Sulfonamides Adverse Effects: photosensitivity, blood dyscrasias, ________ - Answer -
crystalluria
Aminoglycosides AE: _______, nephrotoxicity, ______- - Answer -ototoxicity,
neurotoxicity
What Fluoroquinolone do you give for anrthax? - Answer -Cipro
Cipro can cause _______ and EKG changes with cardiac meds - Answer -tendon
rupture
Rifampin decreases effectiveness of - Answer -oral contraceptives
What med causes C. Diff the most? - Answer -clindamycin
Vancomycin AE: ______ and nephrotoxicity - Answer -ototoxicity
What drugs treat C. Diff>? - Answer -flagyl and vanco
What would you administer with Amphocetarin B? - Answer -antihistamine and
antipyretic
, Antibiotics associated with crystalluria: ________, ______, triamterene - Answer -
sulfonamides, acyclovir
What meds cause photosensitivity? - Answer -tetracyclines, sulfonamides
P450 enzymes are a large class of enzyme systems that metabolize drugs in the _____.
When a patient is taking several drugs metabolized by these systems, drug _____ may
be a problem - Answer -liver, interactions
The time it takes for half of a drug in the body to be eliminated - Answer -half life
______ is a measure of affinity. Affinity refers to the strength of attraction between a
receptor and a drug molecule. - Answer -potency
Drugs with high affinity are more ____ and because these drugs bind effectively at
lower concentrations, _____ doses are needed - Answer -potent, lower
_______ is the ability to produce a desired effect. It is a measure of intrinsic activity.
Drugs with high intrinsic activity have high ______. - Answer -efficacy, efficacy
Drugs that elevate gastric pH will increase ionization of ______ drugs so that they are
not absorbed as easily while decreasing ionization of ______ drugs thus increasing their
absorption. - Answer -acidic, basic
Drugs that decrease peristalsis (antidiarrheals, opioids) can ______ absorption of drugs
given enterally while drugs that promote gastric emptying (prokinetics) and peristalsis
(laxatives) may ______ absorption - Answer -increase, decrease
When drugs compete for limited protein binding sites, the end result will be an ____ in
free (unbound) drug. Only free drug can leave the systemic circulation for distribution;
therefore there will be an increased distribution which can result in a relative over-dose
and possible toxicity - Answer -increase
A drug that is acted upon by an enzyme - Answer -substrate
G6PD is an enzyme that ______ the risk of RBC hemolysis when they are exposed to
oxidizing drugs. When those with G6PD deficiency take drugs such as sulfonamides,
aspirin, and antimalarials they may experience RBC hemolysis, which may be life
threatening. - Answer -reduces
Pregnancy rating scale to identify the risk that taking a drug has on the fetus: A- studies
show no risk. B- There is no evidence of human risk. C- Risk cannot be ruled out. D-
_____ evidence of risk. ___- contraindicated in pregnancy - Answer -positive, X
Drugs that are weak acids are best absorbed in an ______ environment such as gastric
acid because they remain in an nonionized form - Answer -acidic
