1
NSC 830 Advanced Pharmacology
Questions with 100% Correct Answers
Narrow Specturm Correct Answer: Treat limited # of organisms, Less likely to
disrupt normal flora, organism identified.
Broad Specturm Correct Answer: Treats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? Correct Answer: Is antimicrobial therapy indicated,
make a clinical diagnosis, collection of specimens for a cx or lab test, make
microbial diagnosis, select drug.
Extended spectrum Correct Answer: treats multiple organisms, more likely to
disrupt normal flora, used when causative organism is unknown.
Gram positive Correct Answer: Purple, thick layer
Example of gram positive Correct Answer: Group A beta-strep
Strep PNA
Gram negative Correct Answer: Red or pink, thin layer
Example of gram negative Correct Answer: H. influenza
N. Gonoccocus
Atypical Organism Correct Answer: colorless, no layer
:
vPretest - Stuvia US
,2
Example of Atypical organism Correct Answer: Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx Correct
Answer: True
Risk factors for Drug Resistant Strep PNA (DRSP) Correct Answer: Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA Correct Answer: High dose amoxicillin 3-
4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... Correct Answer: Allergy history
(PCN- risk of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
:
vPretest - Stuvia US
, 3
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? Correct Answer: tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? Correct
Answer: Bactericidals
What are bactericidals? Correct Answer: Kills bacteria
What are bacteriostatic? Correct Answer: Restrains production of bacteria. The
patient needs a good immune system.
Minimum inhibitory concentration (MIC) Correct Answer: Min. amount of abx
used to inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... Correct Answer: Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx Correct Answer: Hypersensitivity: (allergic reaction-
rash, itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
:
vPretest - Stuvia US
NSC 830 Advanced Pharmacology
Questions with 100% Correct Answers
Narrow Specturm Correct Answer: Treat limited # of organisms, Less likely to
disrupt normal flora, organism identified.
Broad Specturm Correct Answer: Treats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? Correct Answer: Is antimicrobial therapy indicated,
make a clinical diagnosis, collection of specimens for a cx or lab test, make
microbial diagnosis, select drug.
Extended spectrum Correct Answer: treats multiple organisms, more likely to
disrupt normal flora, used when causative organism is unknown.
Gram positive Correct Answer: Purple, thick layer
Example of gram positive Correct Answer: Group A beta-strep
Strep PNA
Gram negative Correct Answer: Red or pink, thin layer
Example of gram negative Correct Answer: H. influenza
N. Gonoccocus
Atypical Organism Correct Answer: colorless, no layer
:
vPretest - Stuvia US
,2
Example of Atypical organism Correct Answer: Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx Correct
Answer: True
Risk factors for Drug Resistant Strep PNA (DRSP) Correct Answer: Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA Correct Answer: High dose amoxicillin 3-
4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... Correct Answer: Allergy history
(PCN- risk of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
:
vPretest - Stuvia US
, 3
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? Correct Answer: tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? Correct
Answer: Bactericidals
What are bactericidals? Correct Answer: Kills bacteria
What are bacteriostatic? Correct Answer: Restrains production of bacteria. The
patient needs a good immune system.
Minimum inhibitory concentration (MIC) Correct Answer: Min. amount of abx
used to inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... Correct Answer: Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx Correct Answer: Hypersensitivity: (allergic reaction-
rash, itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
:
vPretest - Stuvia US
