APMLE Pharm Questions With Complete Solutions
"-bendazole" Correct Answers Anti parasite (hemelinths)
"-ipramine"
"-Triptyline" Correct Answers TCA
"-mivir" Correct Answers neuramidase inhibitor
"-navir" Correct Answers protease inhibitor
"-ovir" Correct Answers DNA polymerase inhibitor
"-triptan" Correct Answers 5-HT agonist
"-zosin" Correct Answers A1 agoinst
"teplase" Correct Answers *Thrombolytics*
convert plasminogen to plasmin
*Alkylating Agent* Covalently x-link DNA @ guanine N-7
Correct Answers Cyclophosphamide
*antiarrhythmic* blocks activated Na+ channels, decreasing the
rate of cardiac conduction by decreasing the rate of phase 0
depolarization, also blocks muscarinic and alpha 1 receptors
Correct Answers Quinidine
*Antibiotic* bind DNA and topoisomerase II
- St. John's wart is competitive antagonist Correct Answers
Doxorubicin
, Daunorubicin
*Antibiotic* block DNA transcription by RNA polymerase
Correct Answers Actinomycin D
*Antimetabolite* folic acid analogue that inhibits dihydrofolate
reductase Correct Answers Methotrexate
*Antimetabolite* purine (thiol) decrease guanine nucleotides
Correct Answers Azathioprine-6MP-6TG
-allopurinol is a supportive therapy
*Antimetabolite* pyrimidine analogue that inhibits thymidylate
synthetase Correct Answers 5-FU
*Antimetabolite* S-phase specific inhibitor of dCTP; DNA
Polymerase Correct Answers Cytarabine
*Antipsychotic* blocks D2 receptors as Tx for a lot of disorders
Correct Answers Haloperidol
*Immunosuppressant* Antimetabolite precursor of 6-
mercaptopurine that interferes with the metabolism and
synthesis of nucleic acids Correct Answers Azithioprine
- bone marrow suppression, toxic effects increased by
allopurinol
*Immunosuppressant* binds to FK-binding protein Correct
Answers Tacrolimus (FK506)
"-bendazole" Correct Answers Anti parasite (hemelinths)
"-ipramine"
"-Triptyline" Correct Answers TCA
"-mivir" Correct Answers neuramidase inhibitor
"-navir" Correct Answers protease inhibitor
"-ovir" Correct Answers DNA polymerase inhibitor
"-triptan" Correct Answers 5-HT agonist
"-zosin" Correct Answers A1 agoinst
"teplase" Correct Answers *Thrombolytics*
convert plasminogen to plasmin
*Alkylating Agent* Covalently x-link DNA @ guanine N-7
Correct Answers Cyclophosphamide
*antiarrhythmic* blocks activated Na+ channels, decreasing the
rate of cardiac conduction by decreasing the rate of phase 0
depolarization, also blocks muscarinic and alpha 1 receptors
Correct Answers Quinidine
*Antibiotic* bind DNA and topoisomerase II
- St. John's wart is competitive antagonist Correct Answers
Doxorubicin
, Daunorubicin
*Antibiotic* block DNA transcription by RNA polymerase
Correct Answers Actinomycin D
*Antimetabolite* folic acid analogue that inhibits dihydrofolate
reductase Correct Answers Methotrexate
*Antimetabolite* purine (thiol) decrease guanine nucleotides
Correct Answers Azathioprine-6MP-6TG
-allopurinol is a supportive therapy
*Antimetabolite* pyrimidine analogue that inhibits thymidylate
synthetase Correct Answers 5-FU
*Antimetabolite* S-phase specific inhibitor of dCTP; DNA
Polymerase Correct Answers Cytarabine
*Antipsychotic* blocks D2 receptors as Tx for a lot of disorders
Correct Answers Haloperidol
*Immunosuppressant* Antimetabolite precursor of 6-
mercaptopurine that interferes with the metabolism and
synthesis of nucleic acids Correct Answers Azithioprine
- bone marrow suppression, toxic effects increased by
allopurinol
*Immunosuppressant* binds to FK-binding protein Correct
Answers Tacrolimus (FK506)
