TEST BANK FOR Cellular and Molecular Immunology 11th Edition by Abul K. Abbas ISBN:978-0443283581 ALL CHAPTERS COVERED YOUR ULTIMATE GUIDE 100% VERIFIED A+ GRADE ASSURED!!!!!!! NEW LATEST UPDATE!!!!!!!

,Table of Contents
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Chapter 01 Properties and Overview of Immune Responses
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Chapter 02 Cells and Tissues of the Immune System
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Chapter 03 Leukocyte Circulation and Migration Into Tissues
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Chapter 04 Innate Immunity
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Chapter 05 Antibodies and Antigens
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Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
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Histocompatibility Complex Molecules
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Chapter 07 Immune Receptors and Signal Transduction
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Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
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Chapter 09 Activation of T Lymphocytes
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Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
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ChapterGB 11 Differentiation and Functions of CD8+ Effector T Cells
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ChapterGB 12 B Cell Activation and Antibody Production
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ChapterGB 13 Effector Mechanisms of Humoral Immunity
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ChapterGB 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
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ChapterGB 15 Immunologic Tolerance and Autoimmunity
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ChapterGB 16 Immunity to Microbes
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ChapterGB 17 Transplantation Immunology
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ChapterGB 18 Tumor Immunology
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Chapter 19 Hypersensitivity Disorders
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Chapter 20 Allergy
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Chapter 21 Primary and Acquired Immunodeficiencies
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,Chapter 01: Properties and Overview of Immune Responses
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Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
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MULTIPLE CHOICE GB




1. The principal function of the immune system is:
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a. Defense against cancer GB GB


b. Repair of injured tissues GB GB GB


c. Defense against microbial infections GB GB GB


d. Prevention of inflammatory diseases GB GB GB


e. Protection against environmental toxins GB GB GB




ANS: C G B


The immune system has evolved in the setting of selective pressures imposed by mic
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robial infections. Although immune responses to cancer may occur, the concept that
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“immunosurveillance” against cancer is a principal function of the immune system isGB GB GB GB GB GB GB GB GB GB GB G


Bcontroversial. Repair of injured tissues may be a secondary consequence of the imm
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une responses and inflammation. Although the immune system has regulatory feature
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s that are needed to prevent excessive inflammation, prevention of inflammatory dise
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ases is not a primary function. The immune system can protect against microbial toxi
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ns, but it generally does not offer protection against toxins of nonbiologic origin.
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2. Which of the following infectious diseases was prevented by the first succe
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ssful vaccination?
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a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS: C G B


In 1798, Edward Jenner reported the first intentional successful vaccination, which w
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as against smallpox in a boy, using material from the cowpox pustules of a milkmaid.
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In 1980, smallpox was reported to be eradicated worldwide by a vaccination progra
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m. Effective vaccines against tetanus toxin, rubella virus, and poliovirus were develo
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ped in the 20th century and are widely used. There is no effective vaccine against
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Mycobacterium tuberculosis. GB




3. Which of the following is a unique property of the adaptive immune system?
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a. Highly diverse repertoire of specificities for antigens
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b. Self-nonself discrimination GB


c. Recognition of microbial structures by both cell-associated and soluble receptors
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d. Protection against viral infections GB GB GB


e. Responses that have the same kinetics and magnitude on repeated exposure t
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o the same microbe
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ANS: G B A

, Highly diverse repertoires of specificities for antigens are found only in T and B ly
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mphocytes, which are the central cellular components of the adaptive immune system
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. Both the innate and the adaptive immune systems use cell-
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associated and soluble receptors to recognize microbes, display some degree of self-
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nonself discrimination, and protect against viruses. On repeated exposure to the same
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Bmicrobe, the adaptive immune response becomes more rapid and of greater magnitud
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e; this is the manifestation of memory.
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4. Antibodies and T lymphocytes are the respective mediators of which two typ
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es of immunity?
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a. Innate and adaptive GB GB


b. Passive and active GB GB


c. Specific and nonspecific GB GB


d. Humoral and cell-mediated GB GB


e. Adult and neonatal GB GB




ANS: D G B


Both B and T lymphocytes are principal components of adaptive immunity. B lympho
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cytes produce antibodies, which are the recognition and effector molecules of humoral
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immune responses to extracellular pathogens. T cells recognize and promote eradicati
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on of intracellular pathogens in cell-
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mediated immunity. Passive and active immunity both can be mediated by either B or
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BT lymphocytes. Specific immunity is another term for adaptive immunity. Both B and
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BT lymphocytes participate in adult adaptive immunity but are still developing in the
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neonatal period. GB




5. The two major functional classes of effector T lymphocytes are:
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a. Helper T lymphocytes and cytotoxic T lymphocytes
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b. Natural killer cells and cytoWtoWxW
ic.TTlB
yS
mMph.oW
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c. Memory T cells and effector T cells GB GB GB GB GB GB


d. Helper cells and antigen-presenting cells
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e. Cytotoxic T lymphocytes and target cells GB GB GB GB GB




ANS: A G B


T cells can be classified into effector subsets that perform different effector functions.
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Most effector T cells are either helper T lymphocytes, which enhance the responses
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of other immune cells, including phagocytes and B cells, to infections, or cytotoxic
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T lymphocytes, which directly kill infected cells. Natural killer cells are not T lymp
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hocytes.
Antigen-presenting cells usually are not T cells. Memory T cells are not effector T cells.
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6. Which of the following cell types is required for all adaptive humoral immune responses?
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a. Natural killer cells GB GB


b. Dendritic cells GB


c. Cytolytic T lymphocytes GB GB


d. B lymphocytes GB


e. Helper T lymphocytes GB GB




ANS: D G B


Humoral immune responses are antibody-
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mediated immune responses, and all antibodies are made by B lymphocytes and no
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other cell type.
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