UWSA #1 – Questions With A+ Solutions
Save
Terms in this set (100)
What vitamin supplement Vitamin A - highly teratogenic during the 1st trimester
should be avoided during with organogenesis primarily occurs
pregnancy unless
otherwise needed?
Sensitive indicator of apoptosis. Laddering occurs
DNA laddering during karyorrhexis when endonucleases break up DNA
resulting in intervals of 180 base pairs.
Follicular lymphoma - well-established mechanism by
which malignant lyphoid cells avoid apoptosis
Overexpression of BCL2
BCL2 is an antiapoptotic protein
-Anticholinesterse - increases ACh
Physostigmine -Used in anticholinergic toxicity (atropine)
-Crosses the blood-brain barrier (CNS)
No intrinsic tyrosine kinase domain
Cytokine Receptor works via attract and bind, and
autophosphorylate JAK tyrosine kinase. which then
transphosphorylates the receptor (both
JAK-STAT signal
phosphorylated) - docking site for STAT
transduction
Activated JAK catalyzes phosphorylation of STAT.
Activated stat = dimer + dimer formation.
STAT dimers bind to DNA response elements.
Ras signal transduction conducts signals from growth factors and hormones to
pathway the nucleus and stimulates the cell cycle
A series of kinases that are triggered by activated GTP-
MAP kinase pathway bound Ras; the final kinase enters the nucleus, where it
phosphorylates its target proteins.
, TRUE or FALSE: False. There is compensatory hyperfiltration and
Heminephrectomy results hypertrophy of the nephrons in the reamining kidney.
in complete return of GFR However, total GFR increases from 50% to about 80% of
to 100% its original value within several weeks.
either of two masses of erectile
tissue forming the bulk of the
Corpora cavernosa
penis and the clitoris
Visual defect in Bitemporal hemianopia
carniopharyngioma
Increased bicarb secretion and decreased chloride
secretion.
High flow rate of pancreas
Sodium and Potassium remain constant
Psychotic disturbance involving delusions,
hallucinations, or disorganized speech or behavior but
Brief psychotic disorder
lasting less than 1 month; often occurs in reaction to a
stressor.
identifies dysfunction of spinal cord and/or an upper
motor neuron lesion.
Lhermitte's sign
Seen in Vitamin B12 defeciency and in MS
Both copies have to be defective in same cell to allow
tumor to develop. Sporadic retinoblastoma (RB1)
mutations require two somatic gene mutations.
Knudson's two hit
hypothesis
Herditary retinoblastoma are born with a gerline defect
in 1 of their RB1 genes and aquire an additional somatic
mutation early in life for the "2 hit" requirement.
Save
Terms in this set (100)
What vitamin supplement Vitamin A - highly teratogenic during the 1st trimester
should be avoided during with organogenesis primarily occurs
pregnancy unless
otherwise needed?
Sensitive indicator of apoptosis. Laddering occurs
DNA laddering during karyorrhexis when endonucleases break up DNA
resulting in intervals of 180 base pairs.
Follicular lymphoma - well-established mechanism by
which malignant lyphoid cells avoid apoptosis
Overexpression of BCL2
BCL2 is an antiapoptotic protein
-Anticholinesterse - increases ACh
Physostigmine -Used in anticholinergic toxicity (atropine)
-Crosses the blood-brain barrier (CNS)
No intrinsic tyrosine kinase domain
Cytokine Receptor works via attract and bind, and
autophosphorylate JAK tyrosine kinase. which then
transphosphorylates the receptor (both
JAK-STAT signal
phosphorylated) - docking site for STAT
transduction
Activated JAK catalyzes phosphorylation of STAT.
Activated stat = dimer + dimer formation.
STAT dimers bind to DNA response elements.
Ras signal transduction conducts signals from growth factors and hormones to
pathway the nucleus and stimulates the cell cycle
A series of kinases that are triggered by activated GTP-
MAP kinase pathway bound Ras; the final kinase enters the nucleus, where it
phosphorylates its target proteins.
, TRUE or FALSE: False. There is compensatory hyperfiltration and
Heminephrectomy results hypertrophy of the nephrons in the reamining kidney.
in complete return of GFR However, total GFR increases from 50% to about 80% of
to 100% its original value within several weeks.
either of two masses of erectile
tissue forming the bulk of the
Corpora cavernosa
penis and the clitoris
Visual defect in Bitemporal hemianopia
carniopharyngioma
Increased bicarb secretion and decreased chloride
secretion.
High flow rate of pancreas
Sodium and Potassium remain constant
Psychotic disturbance involving delusions,
hallucinations, or disorganized speech or behavior but
Brief psychotic disorder
lasting less than 1 month; often occurs in reaction to a
stressor.
identifies dysfunction of spinal cord and/or an upper
motor neuron lesion.
Lhermitte's sign
Seen in Vitamin B12 defeciency and in MS
Both copies have to be defective in same cell to allow
tumor to develop. Sporadic retinoblastoma (RB1)
mutations require two somatic gene mutations.
Knudson's two hit
hypothesis
Herditary retinoblastoma are born with a gerline defect
in 1 of their RB1 genes and aquire an additional somatic
mutation early in life for the "2 hit" requirement.
