NR 565 Midterm Study Guide with
Complete Solutions
ACE inhibitors contraindications - correct Answer-African American, 2nd/3rd timester
pregnancy, renal disease
ACEI and ARBs can lead to renal failure in who? - correct Answer-Patients w/ bilateral
renal artery stenosis
Alternative treatment strategies for statin intolerant patients - correct Answer-ezetimibe,
fibrates, nicotinic acid, bile acid sequestrates
combo therapy with infrequent statin dosing
dietary changes
switching to a different statin
appropriate intervals for medication adjustments - correct Answer-4-6 weeks is ideal
before adding another drug to the therapy regimen
Beer's Criteria - correct Answer-Criteria for "Potentially Inappropriate Medication Use in
Older Adults"; identifies drugs with a high likelihood of causing adverse effects in older
adults
pg. 62 in textbook for table
Beta Blockers Contraindications - correct Answer-severe HF, Bradycardia, Advanced
Heart block, Hypotension (persistent), cardiogenic shock
BP meds approved for pregnancy - correct Answer-Labetalol and Methyldopa
Carbamazepine drug interactions & dosing considerations - correct Answer-narrow
therapeutic dose (toxicity is a risk)
CCB Mech of action - correct Answer-Promotes relaxation of peripheral arterioles
resulting in a decreased afterload which reduces cardiac oxygen demand
classes of controlled substances: - correct Answer-Anabolic steroids, narcotics,
stimulants, depressants, and hallucinogens
, clinical tools for treating hyperlipidemia - correct Answer-ASCVD risk category,
AHA/ACC, clinical guidelines
CYP450 inducers and inhibitors - correct Answer-inducers:
carbamazepine
phenobarbital
phenytoin
rifampin
griseofulvin
inhibitors:
cimetidine
ciprofloxacin
erythromycin
all azole antifungals
grapefruit juice
isoniazid
ritonavir protease inhibitors
DEA (Federal Drug Enforcement Administration) - correct Answer-regulate drugs and
other substances based on their potential for abuse and dependence
digoxin dosaging adjustments and cautions - correct Answer-start low, risk of toxicity,
requires frequent monitoring of serum levels;
do not use w/ quinidine
drug of choice for lowering LDL - correct Answer-Statins
drug schedules - schedule 2 - correct Answer-combination drugs w/ < 15mg
hydrocodone per dosage unit
High potential for abuse and severe physical/psychological dependence
examples:
Vicodin, cocaine, methamphetamine, methadone, Dilaudid, oxycodone, Meperidine,
Fentanyl, Adderall, Ritalin
drug schedules - schedule 3 - correct Answer-drugs w/ <90 mg of codeine per dosage
unit
abuse would lead to mod-low physical dependence and high psychological dependence
examples: ketamine, tylenol w/ codeine, anabolic steroids, testosterone
Complete Solutions
ACE inhibitors contraindications - correct Answer-African American, 2nd/3rd timester
pregnancy, renal disease
ACEI and ARBs can lead to renal failure in who? - correct Answer-Patients w/ bilateral
renal artery stenosis
Alternative treatment strategies for statin intolerant patients - correct Answer-ezetimibe,
fibrates, nicotinic acid, bile acid sequestrates
combo therapy with infrequent statin dosing
dietary changes
switching to a different statin
appropriate intervals for medication adjustments - correct Answer-4-6 weeks is ideal
before adding another drug to the therapy regimen
Beer's Criteria - correct Answer-Criteria for "Potentially Inappropriate Medication Use in
Older Adults"; identifies drugs with a high likelihood of causing adverse effects in older
adults
pg. 62 in textbook for table
Beta Blockers Contraindications - correct Answer-severe HF, Bradycardia, Advanced
Heart block, Hypotension (persistent), cardiogenic shock
BP meds approved for pregnancy - correct Answer-Labetalol and Methyldopa
Carbamazepine drug interactions & dosing considerations - correct Answer-narrow
therapeutic dose (toxicity is a risk)
CCB Mech of action - correct Answer-Promotes relaxation of peripheral arterioles
resulting in a decreased afterload which reduces cardiac oxygen demand
classes of controlled substances: - correct Answer-Anabolic steroids, narcotics,
stimulants, depressants, and hallucinogens
, clinical tools for treating hyperlipidemia - correct Answer-ASCVD risk category,
AHA/ACC, clinical guidelines
CYP450 inducers and inhibitors - correct Answer-inducers:
carbamazepine
phenobarbital
phenytoin
rifampin
griseofulvin
inhibitors:
cimetidine
ciprofloxacin
erythromycin
all azole antifungals
grapefruit juice
isoniazid
ritonavir protease inhibitors
DEA (Federal Drug Enforcement Administration) - correct Answer-regulate drugs and
other substances based on their potential for abuse and dependence
digoxin dosaging adjustments and cautions - correct Answer-start low, risk of toxicity,
requires frequent monitoring of serum levels;
do not use w/ quinidine
drug of choice for lowering LDL - correct Answer-Statins
drug schedules - schedule 2 - correct Answer-combination drugs w/ < 15mg
hydrocodone per dosage unit
High potential for abuse and severe physical/psychological dependence
examples:
Vicodin, cocaine, methamphetamine, methadone, Dilaudid, oxycodone, Meperidine,
Fentanyl, Adderall, Ritalin
drug schedules - schedule 3 - correct Answer-drugs w/ <90 mg of codeine per dosage
unit
abuse would lead to mod-low physical dependence and high psychological dependence
examples: ketamine, tylenol w/ codeine, anabolic steroids, testosterone
