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DLM(ASCP) EXAM ACTUAL EXAM 250 REAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES|A+ GRADE 2025/2026 (FINANCIAL
MANAGEMENT, OPERATIONS MANAGEMENT, HUMAN RESOURCE
MANAGEMENT, QUALITY MANAGEMENT)/DLM(ASCP) EXAM
PREPARATION/DLM(ASCP)
Elliptocytes are commonly seen in what condition(s)? - ......ANSWER........hereditary
elliptocytosis, iron deficiency, thalassemia
Eosinophil counts are increased in what conditions? - ......ANSWER........allergies,
parasites
Excess Iron is stored where? What does this cause? - ......ANSWER........tissues and body
organs, hemosiderosis, hemochromatosis
Gaucher's disease is characterized by an increase in what?
- ......ANSWER........glucocerebroside
Ham's/Acid Hemolysis testing measures? - ......ANSWER........complement mediated lysis
Heinz body preps measure? - ......ANSWER........the effect of oxidizing agents on
hemoglobin.
Helmet cells are seen in what condition(s)? - ......ANSWER........hemolytic processes
Hemoglobin A is composed of what types of globin chains? - ......ANSWER........alpha,
delta
Hemoglobin A2 is composed of what types of globin chains? - ......ANSWER........alpha,
beta
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Hemoglobin F is composed of what types of globin chains? - ......ANSWER........alpha,
gamma
Hemoglobin H disease is characterized by the deletion of how many alpha genes?
- ......ANSWER........3
Hemoglobin is measured by its conversion to what? By?
- ......ANSWER........cyanmethemoglobin, potassium cyanide, potassium ferricyanide
Hemoglobinopathies are the result of? - ......ANSWER........structural changes to the globin
chains
Hgb Bart's may be present at birth in individuals suffering from what condition?
- ......ANSWER........hemoglobin H disease
How does EDTA work as an anticoagulant? - ......ANSWER........it chelates Ca++
How does heparin work as an anticoagulant? - ......ANSWER........it is an anti-thrombin
agent
How does the value for hemoglobin compare to the value for the hematocrit?
- ......ANSWER........Hgb X 3 = Hct +/-3%
How does the value for RBCs compare to the value for Hgb? - ......ANSWER........RBC X 3 =
Hgb +/-3%
How is the hematocrit measured using automated methods?
- ......ANSWER........calculated from MCV and RBC
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Howell-Jolly bodies are composed of? - ......ANSWER........DNA
Hyper-segmented neutrophils are associated with what condition(s)?
- ......ANSWER........pernicious anemia
Hypo-segmented neutrophils are associated with what condition(s)?
- ......ANSWER........Pelger Huet, pseudo-Pelger Huet, AML, AIDS
If platelet count seems low what would be the corrective action? - ......ANSWER........check
feather edge for clumping and satellitism. (Is an EDTA related phenomenon) If seen redraw
in Na citrate
In a leukemoid reaction, the LAP score is? - ......ANSWER........increased
In a leukemoid reaction, toxic granulation is? - ......ANSWER........increased
In CML, the LAP score is? - ......ANSWER........decreased
In CML, toxic granulation is? - ......ANSWER........decreased
In individuals with beta thalassemia, what other hemoglobin types are produced to make
up for the lack of beta chain synthesis? What type of hemoglobin is decreased in
production (or absent)? - ......ANSWER........A2 and F are increased; A is decreased or
absent
In relative polycythemia, a decrease in what leads to the relative increase in RBCs?
- ......ANSWER........plasma
DLM(ASCP) EXAM ACTUAL EXAM 250 REAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES|A+ GRADE 2025/2026 (FINANCIAL
MANAGEMENT, OPERATIONS MANAGEMENT, HUMAN RESOURCE
MANAGEMENT, QUALITY MANAGEMENT)/DLM(ASCP) EXAM
PREPARATION/DLM(ASCP)
Elliptocytes are commonly seen in what condition(s)? - ......ANSWER........hereditary
elliptocytosis, iron deficiency, thalassemia
Eosinophil counts are increased in what conditions? - ......ANSWER........allergies,
parasites
Excess Iron is stored where? What does this cause? - ......ANSWER........tissues and body
organs, hemosiderosis, hemochromatosis
Gaucher's disease is characterized by an increase in what?
- ......ANSWER........glucocerebroside
Ham's/Acid Hemolysis testing measures? - ......ANSWER........complement mediated lysis
Heinz body preps measure? - ......ANSWER........the effect of oxidizing agents on
hemoglobin.
Helmet cells are seen in what condition(s)? - ......ANSWER........hemolytic processes
Hemoglobin A is composed of what types of globin chains? - ......ANSWER........alpha,
delta
Hemoglobin A2 is composed of what types of globin chains? - ......ANSWER........alpha,
beta
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Hemoglobin F is composed of what types of globin chains? - ......ANSWER........alpha,
gamma
Hemoglobin H disease is characterized by the deletion of how many alpha genes?
- ......ANSWER........3
Hemoglobin is measured by its conversion to what? By?
- ......ANSWER........cyanmethemoglobin, potassium cyanide, potassium ferricyanide
Hemoglobinopathies are the result of? - ......ANSWER........structural changes to the globin
chains
Hgb Bart's may be present at birth in individuals suffering from what condition?
- ......ANSWER........hemoglobin H disease
How does EDTA work as an anticoagulant? - ......ANSWER........it chelates Ca++
How does heparin work as an anticoagulant? - ......ANSWER........it is an anti-thrombin
agent
How does the value for hemoglobin compare to the value for the hematocrit?
- ......ANSWER........Hgb X 3 = Hct +/-3%
How does the value for RBCs compare to the value for Hgb? - ......ANSWER........RBC X 3 =
Hgb +/-3%
How is the hematocrit measured using automated methods?
- ......ANSWER........calculated from MCV and RBC
, 3 of 26
Howell-Jolly bodies are composed of? - ......ANSWER........DNA
Hyper-segmented neutrophils are associated with what condition(s)?
- ......ANSWER........pernicious anemia
Hypo-segmented neutrophils are associated with what condition(s)?
- ......ANSWER........Pelger Huet, pseudo-Pelger Huet, AML, AIDS
If platelet count seems low what would be the corrective action? - ......ANSWER........check
feather edge for clumping and satellitism. (Is an EDTA related phenomenon) If seen redraw
in Na citrate
In a leukemoid reaction, the LAP score is? - ......ANSWER........increased
In a leukemoid reaction, toxic granulation is? - ......ANSWER........increased
In CML, the LAP score is? - ......ANSWER........decreased
In CML, toxic granulation is? - ......ANSWER........decreased
In individuals with beta thalassemia, what other hemoglobin types are produced to make
up for the lack of beta chain synthesis? What type of hemoglobin is decreased in
production (or absent)? - ......ANSWER........A2 and F are increased; A is decreased or
absent
In relative polycythemia, a decrease in what leads to the relative increase in RBCs?
- ......ANSWER........plasma
