Medical Endocrine and Reproductive Physiology PS 3
Study online at https://quizlet.com/_i2081w
1. Organs of Calcium and Phosphate Regulation: bone, kidney, and intestine
2. Calcium and Phosphate: major calcium salt in bones
3. Parathyroid Hormone: a calciotropic peptide hormone that increases plasma Ca
the major stimulus for synthesis and secretion is a fall in plasma Ca levels
4. Chief Cells: principal cells that synthesize PTH
5. Vitamin D Metabolite 1,25(OH)2D3: a calciotropic hormone that supports the actions of PTH to
increase plasma Ca and supports negative feedback over PTH secretion
6. Calcitonin: a peptide hormone that decreases plasma Ca by inhibiting bone breakdown
7. PTH actions: kidney:
promotes Ca reabsorption
decreases Phosphate reabsorption
increases vitamin D metabolite production
bone: promotes bone remodeling with net loss of Ca and Phosphate
8. Osteoblasts: Contain PTH receptors to cause bone resorption when PTH levels are elevated and bone formation
when levels of PTH are low
1/2
Study online at https://quizlet.com/_i2081w
1. Organs of Calcium and Phosphate Regulation: bone, kidney, and intestine
2. Calcium and Phosphate: major calcium salt in bones
3. Parathyroid Hormone: a calciotropic peptide hormone that increases plasma Ca
the major stimulus for synthesis and secretion is a fall in plasma Ca levels
4. Chief Cells: principal cells that synthesize PTH
5. Vitamin D Metabolite 1,25(OH)2D3: a calciotropic hormone that supports the actions of PTH to
increase plasma Ca and supports negative feedback over PTH secretion
6. Calcitonin: a peptide hormone that decreases plasma Ca by inhibiting bone breakdown
7. PTH actions: kidney:
promotes Ca reabsorption
decreases Phosphate reabsorption
increases vitamin D metabolite production
bone: promotes bone remodeling with net loss of Ca and Phosphate
8. Osteoblasts: Contain PTH receptors to cause bone resorption when PTH levels are elevated and bone formation
when levels of PTH are low
1/2
