ANCC AGPCNP PRACTICE QUESTIONS WITH
CORRECT ANSWERS
An 18-year-
old female patient is being followed up for acne by the nurse practitioner. During the facial exam, pap
ules and pustules are noted mostly on the forehead and the chin areas. The patient has been using over
-the-
counter topical antibiotic gels and medicated soap daily for 6 months without much improvement. The
nurse practitioner will recommend:
a. Isotretinoin (Accutane)
b. Tetracycline (Sumycin)
c. Clindamycin topical solution (Cleocin- T)
d. Minoxidil (Rogaine) - correct answer-b. Tetracycline (Sumycin)
First-line treatment for acne vulgaris includes over-the-
counter medicated soap and water with topical antibiotic gels. The next step in treatment would be the
initiation of oral tetracycline.
A young adult presents for reassessment of uncontrolled asthma symptoms. The patient is currently tak
ing an inhaled short-acting beta2-
agonist (SABA) as needed and reports daytime symptoms more than 3 days/week, but not daily, and ni
ghttime awakenings 4 to 5 times/week. The patient's forced expiratory volume (FEV1) is 80% of predi
cted. The nurse practitioner upgrades the patient to the next stage of treatment, which includes:
a. Budesonide with formoterol
b. Budesonide with montelukast
c. Cromolyn or nedocromil
d. Fluticasone with salmeterol - correct answer-a. Budesonide with formoterol.
The patient has moved from step 2 to step 3 on the asthma classification scale. Therefore, a low-
dose inhaled corticosteroid (ICS) plus long-acting beta-
agonist (LABA) such as budesonide with formoterol is an appropriate starting point. Fluticasone with s
almeterol is prescribed if the patient is at step 4; budesonide with montelukast is an alternative. Cromo
lyn and nedocromil have been discontinued in the United States.
,Which of the following drugs can increase the risk of bleeding in patients who are receiving anticoagul
ation therapy with warfarin sodium (Coumadin)?
a. Trimethoprim-sulfamethoxazole (Bactrim DS)
b. Carafate (Sucralfate)
c. Losartan (Cozaar)
d. Furosemide (Lasix) - correct answer-a. Trimethoprim-sulfamethoxazole (Bactrim DS).
Warfarin sodium (Coumadin) interacts with Bactrim and will increase the risk of bleeding; therefore, c
oncurrent use is contraindicated.
A 22-year-old woman is going on a 5-
day cruise for her honeymoon. She reports a history of severe motion sickness. Which of the following
medicines can be prescribed for motion sickness?
a. Dimenhydrinate (Dramamine)
b. Metoclopramide (Reglan)
c. Ondansetron (Zofran)
d. Scopolamine patch (Transderm Scop) - correct answer-d. Scopolamine patch (Transderm Scop)
Scopolamine patch (Transderm Scop) is a prescription medicine that is used for motion/sea sickness. It
is a small, circular patch that is placed behind the ear and is effective for 3 days. Advise the patient to
apply it 4 hours before the trip to be effective. Because the question is asking about a "prescribed" me
dication, an over-the-
counter (OTC) medicine, such as Dramamine, is an incorrect response. Zofran is indicated for cancer-
related nausea and vomiting (chemotherapy, radiation, surgery).
The nurse practitioner is completing a health assessment on a 15-year-
old female patient who is in the office for herAannual physical. The patient reports feelings of hopeless
ness and sadness for several months, no history of suicidal ideations, and a struggle with anorexia. The
patient scores an 11 on Beck's Depression Inventory. Which antidepressant will the nurse practitioner
prescribe?
a. Sertraline (Zoloft)
,b. Lithium L carbonate L (Eskalith)
c. Bupropion L(Wellbutrin)
d. Escitalopram L(Lexapro) L - L correct L answer-d. L Escitalopram L [Lexapro]
Escitalopram Lis La Lsafe Lantidepressant Lfor Lan Ladolescent Lwho Lhas Lsevere Ldepression Land Lno
Lhistory Lof Lsui Lcidal Lideations. LSertraline Lis Lnot La Lsafe Loption Lfor Lpatients Lyounger Lthan L24
Lyears Lof Lage Lbecause Lof Lincr Leased Lrisk L of L suicidal L ideation. L Bupropion L is L an L atypical
L antidepressant L and L is L not L a L first-
line Ltherapy Lfor Ldepression. LIt Lis Lcontraindicated Lin Lpatients Lwith Lanorexia Lnervosa. LLithium Lis
Lindicated Lfor Lpatients Lwith Lbipolar Ldisorder.
Which Linitial Ltreatment Lwill Lthe Lnurse Lpractitioner Lprescribe Lto La
L23-year- Lold Lfemale Lallergic Lto Lsulfa Ldrugs Lwho Lis Ldiagnosed
Lwith Lacute Lcystitis?
a. Cephalexin L (Keflex) L 500 L mg L BID L × L 5 L days
b. Ciprofloxacin L (Cipro) L 250 L mg L BID L × L 3 L days
c. Nitrofurantoin L (Macrobid) L 100 L mg L BID L × L 5 L days
d. Amoxicillin L 500 L mg L BID L × L 5 L days L - L correct L answer-
c. L Nitrofurantoin L (Macrobid) L 100 L mg L BID L × L 5 L days
Nitrofurantoin Lcan L be L safely L administered L to L a L patient Lwith L a L sulfa L allergy L to Ltreat L acute
Lcystitis L and Lis L t Lhe Lfirst Lline Lof Ltreatment. LCephalexin Land Lamoxicillin Lare Lbeta-
lactam Lantibiotics Lthat Lcan Lbe Lprescribed Lfor La Lpatient Lwho Lhas Lan Lallergy Lto Lsulfa Land
Lnitrofurantoin. LA Lfluoroquinolone, Lsuch Las Lciprofloxacin, Lis Lrecommended Lfor La Lpatient Lwho
Lis Lallergic Lto Lsulfa Land Lbeta- Llactam L drugs Lor Lhas La Lsulfa Lallergy Land La Lknown Lresistance
Lto Lbeta-lactam L antibiotics.
A L68-year-old L patient Lrecently L prescribed L caridopa-
levodopa L (Sinemet) Ltells L the L nurse L practitionerAthat Lhe Lhas L been L bloated L and L experiencing
L difficulty L wit Lh Lbowel Lmovements. LWhich Lmedication Lwill Lthe Lnurse Lpractitioner Lconsider
Lincorporating Linto Lthe Ltreat Lment Lplan?
a. Senna
b. Methylnaltrexone
c. Magnesium Lcitrate
d. Polyethylene L glycol L - L correct L answer-d. L Polyethylene L glycol
, Levodopa, Lan L antiparkinsonian L drug, L can L cause L constipation L in Lan L older L patient. L The L first-
line Ltreatment Lfor Lthe Lpatient's Lconstipation Lis Losmotic Llaxatives Lsuch Las Lpolyethylene Lglycol.
LSenna Lis La L stimulant Llaxative Lthat Lis La Lsecond-
line Ltreatment Lfor Lconstipation Lin Lan Lolder Ladult. LMethylnaltrexone Lis La Lperipherally
Lacting Lmu- Lopioid Lantagonist Lthat Lacts Lon Lthe Lgastrointestinal Ltract Lto Ldecrease
Lopioid-
induced L constipation. L Magnesium-
based Llaxatives L(e.g., Lmagnesium Lcitrate) Ltaken Lover Lthe Llong Lterm Lshould Lbe Lavoided Lbecause
Lof Lthe Lpo L tential Lof Ltoxicity.
A Lpatient Lrecently L returned Lfrom L a L trip L to L Africa L and Lis L experiencing L 10 L to L 12 L loose
L stools L every L day. LT Lhe Lpatient Ltakes Lmetformin Levery Lmorning Land Lotherwise Lis Lin Lgood
Lhealth. LWhich Lmedication Lwill Lthe L nurse Lpractitioner Lprescribe Lto Ltreat Lthe Ldiarrhea?
a. Levofloxacin Ldaily
b. Ofloxacin LBID
c. Trimethoprim-sulfamethoxazole L BID
d. Ciprofloxacin L in L a L single L dose L - L correct L answer-d. L Ciprofloxacin L in L a L single L dose
The L patient L most L likely L has L traveler's L diarrhea, L given L the L history L of L a L recent L return L from
L another L countr
y. LThe Lpatient's Ltreatment Lshould Lbe Lbased Lon Lfunctional Limpact Lof Lsymptoms Land Lnot
Lfrequency Lof Lsym L ptoms, Lwhich Lis Lnot Lindicated Lin Lthe Lquestion. LThe Lpatient Llikely Lhas
Lmoderate Lacute Ltraveler's Ldiarrhea, L which Lcan Lbe Ltreated Lwith Lloperamide Las Lmonotherapy Lor
Lwith Ladjunctive Lantibiotic Ltherapy. LThe Lpatient L is L taking L metformin L daily L for L diabetes, L so
L risk L of L precipitating L hypoglycemia L is L lower L than L with L other Loral L antidiabetic L agents.
L Because L it L can L be L given L in L a L single L dose, L ciprofloxacin L would L be L the L appropriat Le
Lchoice Lfor Lreducing Lexposure Land Lmicrobiome Lcolonization Ldisruption. LLevofloxacin Land
Lofloxacin Lre Lquire Lone Lto Lthree Ldoses. LTrimethoprim-
sulfamethoxazole Lis La Lsulfonamide Land Lwould Lbe Lappropriate Ltreatment Lfor Lcyclosporiasis Lbut
Lnot Lgiardi Lasis, Lwhich Lis Lthe Lmost Lcommon Lparasitic Lcause Lof Ltraveler's Ldiarrhea.
A L patient L newly L diagnosed L with L diabetes L reports L severe L hives L and L swollen L lips L after
L taking L Bactrim L for La Lbladder Linfection L2 Lmonths Lago. LWhich Lof Lthe Lfollowing Lstatements Lis
Lcorrect?
a. The L patient L cannot L take L any L pills L in L the L sulfonylurea L class
b. The L patient L can L take L some L of L the L pills L in L the L sulfonylurea L class
c. The L patient L can L take L any L of L the L pills L in L the L sulfonylurea L class
d. None L of L the L above L - L correct L answer-c. L The L patient L can L take L any L of L the L pills L in L the
L sulfonylurea L class
CORRECT ANSWERS
An 18-year-
old female patient is being followed up for acne by the nurse practitioner. During the facial exam, pap
ules and pustules are noted mostly on the forehead and the chin areas. The patient has been using over
-the-
counter topical antibiotic gels and medicated soap daily for 6 months without much improvement. The
nurse practitioner will recommend:
a. Isotretinoin (Accutane)
b. Tetracycline (Sumycin)
c. Clindamycin topical solution (Cleocin- T)
d. Minoxidil (Rogaine) - correct answer-b. Tetracycline (Sumycin)
First-line treatment for acne vulgaris includes over-the-
counter medicated soap and water with topical antibiotic gels. The next step in treatment would be the
initiation of oral tetracycline.
A young adult presents for reassessment of uncontrolled asthma symptoms. The patient is currently tak
ing an inhaled short-acting beta2-
agonist (SABA) as needed and reports daytime symptoms more than 3 days/week, but not daily, and ni
ghttime awakenings 4 to 5 times/week. The patient's forced expiratory volume (FEV1) is 80% of predi
cted. The nurse practitioner upgrades the patient to the next stage of treatment, which includes:
a. Budesonide with formoterol
b. Budesonide with montelukast
c. Cromolyn or nedocromil
d. Fluticasone with salmeterol - correct answer-a. Budesonide with formoterol.
The patient has moved from step 2 to step 3 on the asthma classification scale. Therefore, a low-
dose inhaled corticosteroid (ICS) plus long-acting beta-
agonist (LABA) such as budesonide with formoterol is an appropriate starting point. Fluticasone with s
almeterol is prescribed if the patient is at step 4; budesonide with montelukast is an alternative. Cromo
lyn and nedocromil have been discontinued in the United States.
,Which of the following drugs can increase the risk of bleeding in patients who are receiving anticoagul
ation therapy with warfarin sodium (Coumadin)?
a. Trimethoprim-sulfamethoxazole (Bactrim DS)
b. Carafate (Sucralfate)
c. Losartan (Cozaar)
d. Furosemide (Lasix) - correct answer-a. Trimethoprim-sulfamethoxazole (Bactrim DS).
Warfarin sodium (Coumadin) interacts with Bactrim and will increase the risk of bleeding; therefore, c
oncurrent use is contraindicated.
A 22-year-old woman is going on a 5-
day cruise for her honeymoon. She reports a history of severe motion sickness. Which of the following
medicines can be prescribed for motion sickness?
a. Dimenhydrinate (Dramamine)
b. Metoclopramide (Reglan)
c. Ondansetron (Zofran)
d. Scopolamine patch (Transderm Scop) - correct answer-d. Scopolamine patch (Transderm Scop)
Scopolamine patch (Transderm Scop) is a prescription medicine that is used for motion/sea sickness. It
is a small, circular patch that is placed behind the ear and is effective for 3 days. Advise the patient to
apply it 4 hours before the trip to be effective. Because the question is asking about a "prescribed" me
dication, an over-the-
counter (OTC) medicine, such as Dramamine, is an incorrect response. Zofran is indicated for cancer-
related nausea and vomiting (chemotherapy, radiation, surgery).
The nurse practitioner is completing a health assessment on a 15-year-
old female patient who is in the office for herAannual physical. The patient reports feelings of hopeless
ness and sadness for several months, no history of suicidal ideations, and a struggle with anorexia. The
patient scores an 11 on Beck's Depression Inventory. Which antidepressant will the nurse practitioner
prescribe?
a. Sertraline (Zoloft)
,b. Lithium L carbonate L (Eskalith)
c. Bupropion L(Wellbutrin)
d. Escitalopram L(Lexapro) L - L correct L answer-d. L Escitalopram L [Lexapro]
Escitalopram Lis La Lsafe Lantidepressant Lfor Lan Ladolescent Lwho Lhas Lsevere Ldepression Land Lno
Lhistory Lof Lsui Lcidal Lideations. LSertraline Lis Lnot La Lsafe Loption Lfor Lpatients Lyounger Lthan L24
Lyears Lof Lage Lbecause Lof Lincr Leased Lrisk L of L suicidal L ideation. L Bupropion L is L an L atypical
L antidepressant L and L is L not L a L first-
line Ltherapy Lfor Ldepression. LIt Lis Lcontraindicated Lin Lpatients Lwith Lanorexia Lnervosa. LLithium Lis
Lindicated Lfor Lpatients Lwith Lbipolar Ldisorder.
Which Linitial Ltreatment Lwill Lthe Lnurse Lpractitioner Lprescribe Lto La
L23-year- Lold Lfemale Lallergic Lto Lsulfa Ldrugs Lwho Lis Ldiagnosed
Lwith Lacute Lcystitis?
a. Cephalexin L (Keflex) L 500 L mg L BID L × L 5 L days
b. Ciprofloxacin L (Cipro) L 250 L mg L BID L × L 3 L days
c. Nitrofurantoin L (Macrobid) L 100 L mg L BID L × L 5 L days
d. Amoxicillin L 500 L mg L BID L × L 5 L days L - L correct L answer-
c. L Nitrofurantoin L (Macrobid) L 100 L mg L BID L × L 5 L days
Nitrofurantoin Lcan L be L safely L administered L to L a L patient Lwith L a L sulfa L allergy L to Ltreat L acute
Lcystitis L and Lis L t Lhe Lfirst Lline Lof Ltreatment. LCephalexin Land Lamoxicillin Lare Lbeta-
lactam Lantibiotics Lthat Lcan Lbe Lprescribed Lfor La Lpatient Lwho Lhas Lan Lallergy Lto Lsulfa Land
Lnitrofurantoin. LA Lfluoroquinolone, Lsuch Las Lciprofloxacin, Lis Lrecommended Lfor La Lpatient Lwho
Lis Lallergic Lto Lsulfa Land Lbeta- Llactam L drugs Lor Lhas La Lsulfa Lallergy Land La Lknown Lresistance
Lto Lbeta-lactam L antibiotics.
A L68-year-old L patient Lrecently L prescribed L caridopa-
levodopa L (Sinemet) Ltells L the L nurse L practitionerAthat Lhe Lhas L been L bloated L and L experiencing
L difficulty L wit Lh Lbowel Lmovements. LWhich Lmedication Lwill Lthe Lnurse Lpractitioner Lconsider
Lincorporating Linto Lthe Ltreat Lment Lplan?
a. Senna
b. Methylnaltrexone
c. Magnesium Lcitrate
d. Polyethylene L glycol L - L correct L answer-d. L Polyethylene L glycol
, Levodopa, Lan L antiparkinsonian L drug, L can L cause L constipation L in Lan L older L patient. L The L first-
line Ltreatment Lfor Lthe Lpatient's Lconstipation Lis Losmotic Llaxatives Lsuch Las Lpolyethylene Lglycol.
LSenna Lis La L stimulant Llaxative Lthat Lis La Lsecond-
line Ltreatment Lfor Lconstipation Lin Lan Lolder Ladult. LMethylnaltrexone Lis La Lperipherally
Lacting Lmu- Lopioid Lantagonist Lthat Lacts Lon Lthe Lgastrointestinal Ltract Lto Ldecrease
Lopioid-
induced L constipation. L Magnesium-
based Llaxatives L(e.g., Lmagnesium Lcitrate) Ltaken Lover Lthe Llong Lterm Lshould Lbe Lavoided Lbecause
Lof Lthe Lpo L tential Lof Ltoxicity.
A Lpatient Lrecently L returned Lfrom L a L trip L to L Africa L and Lis L experiencing L 10 L to L 12 L loose
L stools L every L day. LT Lhe Lpatient Ltakes Lmetformin Levery Lmorning Land Lotherwise Lis Lin Lgood
Lhealth. LWhich Lmedication Lwill Lthe L nurse Lpractitioner Lprescribe Lto Ltreat Lthe Ldiarrhea?
a. Levofloxacin Ldaily
b. Ofloxacin LBID
c. Trimethoprim-sulfamethoxazole L BID
d. Ciprofloxacin L in L a L single L dose L - L correct L answer-d. L Ciprofloxacin L in L a L single L dose
The L patient L most L likely L has L traveler's L diarrhea, L given L the L history L of L a L recent L return L from
L another L countr
y. LThe Lpatient's Ltreatment Lshould Lbe Lbased Lon Lfunctional Limpact Lof Lsymptoms Land Lnot
Lfrequency Lof Lsym L ptoms, Lwhich Lis Lnot Lindicated Lin Lthe Lquestion. LThe Lpatient Llikely Lhas
Lmoderate Lacute Ltraveler's Ldiarrhea, L which Lcan Lbe Ltreated Lwith Lloperamide Las Lmonotherapy Lor
Lwith Ladjunctive Lantibiotic Ltherapy. LThe Lpatient L is L taking L metformin L daily L for L diabetes, L so
L risk L of L precipitating L hypoglycemia L is L lower L than L with L other Loral L antidiabetic L agents.
L Because L it L can L be L given L in L a L single L dose, L ciprofloxacin L would L be L the L appropriat Le
Lchoice Lfor Lreducing Lexposure Land Lmicrobiome Lcolonization Ldisruption. LLevofloxacin Land
Lofloxacin Lre Lquire Lone Lto Lthree Ldoses. LTrimethoprim-
sulfamethoxazole Lis La Lsulfonamide Land Lwould Lbe Lappropriate Ltreatment Lfor Lcyclosporiasis Lbut
Lnot Lgiardi Lasis, Lwhich Lis Lthe Lmost Lcommon Lparasitic Lcause Lof Ltraveler's Ldiarrhea.
A L patient L newly L diagnosed L with L diabetes L reports L severe L hives L and L swollen L lips L after
L taking L Bactrim L for La Lbladder Linfection L2 Lmonths Lago. LWhich Lof Lthe Lfollowing Lstatements Lis
Lcorrect?
a. The L patient L cannot L take L any L pills L in L the L sulfonylurea L class
b. The L patient L can L take L some L of L the L pills L in L the L sulfonylurea L class
c. The L patient L can L take L any L of L the L pills L in L the L sulfonylurea L class
d. None L of L the L above L - L correct L answer-c. L The L patient L can L take L any L of L the L pills L in L the
L sulfonylurea L class
