TEST BANK for Fundamentals of
d d d d
Molecular Virology 2nd Edition by
d d d d d
, Acheson.
d
Package Title: Testbank
d d
Course Title: Acheson 2nd edition
d d d d
Chapter Number: 01
d d d
Question type: Multiple Choice
d d d
1) Which of the following terms describes the protein shell that surrounds the viral genome?
d d d d d d d d d d d d d
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere
Answer: a
d d
2) Which of the following would not be a nucleic acid form found in a viral genome?
d d d d d d d d d d d d d d d
a) dsDNA
b) ssDNA
c) dsRNA
d) ssRNA
e) an RNA:DNA hybrid
d d
Answer: e
d d
3) Which of the following is an enzyme that most RNA viruses encode in their genome?
d d d d d d d d d d d d d d
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase
Answer: b
d d
4) Viruses play a major role in the ecology of the ocean by doing which of the following?
d d d d d d d d d d d d d d d d
a) By infecting photosynthetic bacteria and increasing their growth.
d d d d d d d
,b) By infecting harmful bacteria found in the ocean and limiting their growth.
d d d d d d d d d d d
c) By killing off fish and preventing them from becoming too plentiful.
d d d d d d d d d d
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
d d d d d d d d d d d d
e) All of the above statements are correct.
d d d d d d
Answer: d d
5) If you wanted to show that an infectious agent is a virus, what experiment could you do?
d d d d d d d d d d d d d d d d
a) Show that the agent can be seen under a light microscope.
d d d d d d d d d d
b) Show that agent contains a lipid membrane.
d d d d d d
c) Show that the agent can form single colonies on an agar plate.
d d d d d d d d d d d
d) Show that the agent can be diluted and can still cause disease in an animal.
d d d d d d d d d d d d d d
e) Show that the agent can pass through a porcelain filter and is still infectious.
d d d d d d d d d d d d d
Answer: e d
6) What does the word “virus” mean in Latin?
d d d d d d d
a) infectious agent d
b) liquid
c) poison
d) death
e) disease
Answer:
d
c
d
7) The word “phage” is a shortened version of the name of a virus that can infect which type of
d d d d d d d d d d d d d d d d d d
organism?
a) bacterial cell d
b) human cell d
c) eukaryotic cell d
d) plant cell d
e) inset cell d
Answer: a
d d
8) The study of which group of viruses led to the discovery of cellular genes that can promoter cancer
d d d d d d d d d d d d d d d d d
in animal cells?
d d d
a) papillomaviruses
b) retroviruses
c) adneoviruses
d) polyomaviruses
, e) picornaviruses
Answer: b
d d
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
d d d d d d d d d d d d d d d d d d
put on top of the cells after they have been infected with the diluted virus. What is the major purpose
d d d d d d d d d d d d d d d d d d d d
of this agar layer?
d d d d
a) It helps to feed the cells as they grow.
d d d d d d d d
b) It promotes the replication of the virus.
d d d d d d
c) It makes the infected cells easier to visualize.
d d d d d d d
d) It limits the movement of virus particles.
d d d d d d
e) All of the above are correct.
d d d d d
Answer: d d
10) To start an experiment, you do an infection by putting 0.5 ml of a virus stock that has a titer of 6
d d d d d d d d d d d d d d d d d d d d d
x 107 pfu/ml onto a plate of animal cells that contains 5 x 106 cells. What is the multiplicity of infection
d d d d d d d d d d d d d d d d d d d d d
for this experiment?
d d d
a) 12
b) 6
c) 5
d) 3
e) 1
Answer:
d
b
d
11) During a single growth cycle experiment, the titer of extracellular and intracellular virus drops in
d d d d d d d d d d d d d d
the first hour. What explains this observation?
d d d d d d d
a) The virus is inactivated by antibodies in the medium.
d d d d d d d d
b) The virus is inactivated by cellular enzymes.
d d d d d d
c) The virus enters the cell and is uncoated.
d d d d d d d
d) The virus binds to the cells in the dish and can’t be released.
d d d d d d d d d d d d
e) The cell’s antiviral defenses prevent replication of the virus
d d d d d d d d
Answer: c d
12) What is another term for an RNA-dependent-DNA-polymerase?
d d d d d d
a) DNA polymerase d
b) RNA polymerase II d d
d d d d
Molecular Virology 2nd Edition by
d d d d d
, Acheson.
d
Package Title: Testbank
d d
Course Title: Acheson 2nd edition
d d d d
Chapter Number: 01
d d d
Question type: Multiple Choice
d d d
1) Which of the following terms describes the protein shell that surrounds the viral genome?
d d d d d d d d d d d d d
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere
Answer: a
d d
2) Which of the following would not be a nucleic acid form found in a viral genome?
d d d d d d d d d d d d d d d
a) dsDNA
b) ssDNA
c) dsRNA
d) ssRNA
e) an RNA:DNA hybrid
d d
Answer: e
d d
3) Which of the following is an enzyme that most RNA viruses encode in their genome?
d d d d d d d d d d d d d d
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase
Answer: b
d d
4) Viruses play a major role in the ecology of the ocean by doing which of the following?
d d d d d d d d d d d d d d d d
a) By infecting photosynthetic bacteria and increasing their growth.
d d d d d d d
,b) By infecting harmful bacteria found in the ocean and limiting their growth.
d d d d d d d d d d d
c) By killing off fish and preventing them from becoming too plentiful.
d d d d d d d d d d
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
d d d d d d d d d d d d
e) All of the above statements are correct.
d d d d d d
Answer: d d
5) If you wanted to show that an infectious agent is a virus, what experiment could you do?
d d d d d d d d d d d d d d d d
a) Show that the agent can be seen under a light microscope.
d d d d d d d d d d
b) Show that agent contains a lipid membrane.
d d d d d d
c) Show that the agent can form single colonies on an agar plate.
d d d d d d d d d d d
d) Show that the agent can be diluted and can still cause disease in an animal.
d d d d d d d d d d d d d d
e) Show that the agent can pass through a porcelain filter and is still infectious.
d d d d d d d d d d d d d
Answer: e d
6) What does the word “virus” mean in Latin?
d d d d d d d
a) infectious agent d
b) liquid
c) poison
d) death
e) disease
Answer:
d
c
d
7) The word “phage” is a shortened version of the name of a virus that can infect which type of
d d d d d d d d d d d d d d d d d d
organism?
a) bacterial cell d
b) human cell d
c) eukaryotic cell d
d) plant cell d
e) inset cell d
Answer: a
d d
8) The study of which group of viruses led to the discovery of cellular genes that can promoter cancer
d d d d d d d d d d d d d d d d d
in animal cells?
d d d
a) papillomaviruses
b) retroviruses
c) adneoviruses
d) polyomaviruses
, e) picornaviruses
Answer: b
d d
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
d d d d d d d d d d d d d d d d d d
put on top of the cells after they have been infected with the diluted virus. What is the major purpose
d d d d d d d d d d d d d d d d d d d d
of this agar layer?
d d d d
a) It helps to feed the cells as they grow.
d d d d d d d d
b) It promotes the replication of the virus.
d d d d d d
c) It makes the infected cells easier to visualize.
d d d d d d d
d) It limits the movement of virus particles.
d d d d d d
e) All of the above are correct.
d d d d d
Answer: d d
10) To start an experiment, you do an infection by putting 0.5 ml of a virus stock that has a titer of 6
d d d d d d d d d d d d d d d d d d d d d
x 107 pfu/ml onto a plate of animal cells that contains 5 x 106 cells. What is the multiplicity of infection
d d d d d d d d d d d d d d d d d d d d d
for this experiment?
d d d
a) 12
b) 6
c) 5
d) 3
e) 1
Answer:
d
b
d
11) During a single growth cycle experiment, the titer of extracellular and intracellular virus drops in
d d d d d d d d d d d d d d
the first hour. What explains this observation?
d d d d d d d
a) The virus is inactivated by antibodies in the medium.
d d d d d d d d
b) The virus is inactivated by cellular enzymes.
d d d d d d
c) The virus enters the cell and is uncoated.
d d d d d d d
d) The virus binds to the cells in the dish and can’t be released.
d d d d d d d d d d d d
e) The cell’s antiviral defenses prevent replication of the virus
d d d d d d d d
Answer: c d
12) What is another term for an RNA-dependent-DNA-polymerase?
d d d d d d
a) DNA polymerase d
b) RNA polymerase II d d
