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NSG 530 Exam 1 Advanced Pathophysiology-Wilkes Newest
2025/2026 Complete Questions And Correct Detailed Answers
(Verified Answers) |Brand New Version!!
Interphase - ANS-cell feeds, metabolizes and grows while replicating
DNA in preparation for mitosis
Prophase - ANS-first appearance of chromosomes (will be 92)
Metaphase - ANS-Centrioles pull chromosomes to opposite sides of cell
(chromatid) - 46 each side
Anaphase - ANS-Centromeres split and sister chromatids are pulled
apart
Telophase - ANS-New nuclear membrane formed around each group of
46 chromosomes *When it goes right, euploid cells are produced*
Nondisjunction - ANS-Error in meiosis in which homologous
chromosomes fail to separate.
Polyploidy - ANS-condition in which an organism has extra sets of
chromosomes
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Triploidy - ANS-when an organism has three copies of every chromsome
instead of two
Tetrapoloidy - ANS-euploid has 92 chromosomes and fetus usually does
not survive
Huntington's disease - ANS-Single gene disorder (trinucleotide repeat
mutation)
Autosomal dominant (50% chance of passing it on)
Progressive neurologic disease with late onset (40s)
Prevention- genetic testing for pregnancy planning
Cystic fibrosis - ANS-Single gene disorder (CFTR gene mutation)
Autosomal recessive
Most common in white children
Defective transport of chloride ions cause salt imbalance- thickened
secretions, digestive issues, malnutrition. Males and females
Must inherit two copies of gene (1 from each parent)
Turner syndrome - ANS-XO chromosomal disorder, monosomy of X-
affects females
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Short stature, webbed neck, undeveloped breasts but female genitalia,
usually sterile
Down syndrome - ANS-Chromosomal disorder, trisomy 21
Affects both sexes
Intellectual disability, poor muscle tone, low nasal bridge, low set ears,
protruding tongue, epicanthal fold
Fragile X syndrome - ANS-Chromosomal disorder (break in long arm of
X)
Higher prevalence in males
Intellectual disability
Klinefelter syndrome - ANS-(XXY) chromosomal disorder 1:1000 male
births
Male appearance, sparse body hair, mild intellectual disability
Atrophy - ANS-Decrease in cell size
"When cast is removed from left calf, it is smaller than the right calf"
Hypertrophy - ANS-Increase in cell size
NSG 530 Exam 1 Advanced Pathophysiology-Wilkes Newest
2025/2026 Complete Questions And Correct Detailed Answers
(Verified Answers) |Brand New Version!!
Interphase - ANS-cell feeds, metabolizes and grows while replicating
DNA in preparation for mitosis
Prophase - ANS-first appearance of chromosomes (will be 92)
Metaphase - ANS-Centrioles pull chromosomes to opposite sides of cell
(chromatid) - 46 each side
Anaphase - ANS-Centromeres split and sister chromatids are pulled
apart
Telophase - ANS-New nuclear membrane formed around each group of
46 chromosomes *When it goes right, euploid cells are produced*
Nondisjunction - ANS-Error in meiosis in which homologous
chromosomes fail to separate.
Polyploidy - ANS-condition in which an organism has extra sets of
chromosomes
,2|Page
Triploidy - ANS-when an organism has three copies of every chromsome
instead of two
Tetrapoloidy - ANS-euploid has 92 chromosomes and fetus usually does
not survive
Huntington's disease - ANS-Single gene disorder (trinucleotide repeat
mutation)
Autosomal dominant (50% chance of passing it on)
Progressive neurologic disease with late onset (40s)
Prevention- genetic testing for pregnancy planning
Cystic fibrosis - ANS-Single gene disorder (CFTR gene mutation)
Autosomal recessive
Most common in white children
Defective transport of chloride ions cause salt imbalance- thickened
secretions, digestive issues, malnutrition. Males and females
Must inherit two copies of gene (1 from each parent)
Turner syndrome - ANS-XO chromosomal disorder, monosomy of X-
affects females
, 3|Page
Short stature, webbed neck, undeveloped breasts but female genitalia,
usually sterile
Down syndrome - ANS-Chromosomal disorder, trisomy 21
Affects both sexes
Intellectual disability, poor muscle tone, low nasal bridge, low set ears,
protruding tongue, epicanthal fold
Fragile X syndrome - ANS-Chromosomal disorder (break in long arm of
X)
Higher prevalence in males
Intellectual disability
Klinefelter syndrome - ANS-(XXY) chromosomal disorder 1:1000 male
births
Male appearance, sparse body hair, mild intellectual disability
Atrophy - ANS-Decrease in cell size
"When cast is removed from left calf, it is smaller than the right calf"
Hypertrophy - ANS-Increase in cell size
