What does the autonomic nervous system do? - Answers -controls cardiac muscle, smooth
muscle and glandular secretion
-it is divided into the sympathetic and parasympathetic systems
What does sympathetic system do? - Answers "fight-or-flight," expends energy, increase HR,
dilates pupils and bronchi, decreases secretions
What does the parasympathetic systems do? - Answers dominates at rest, conserves energy,
decreases HR, increases tract functions, constricts pupils
What are the neurons responsible for? - Answers autonomic neurotransmission
Where do the presynaptic neurons lie? - Answers brain-->ganglia
Where do the postsynaptic neurons lie? - Answers ganglia--> effector organs
What are processes involved in neurotransmission? - Answers -synthesis of neurotransmitters
(NT)
-packaging of NTs in presynaptic terminals
-stimulation of presynaptic nerve/release of NT
-diffusion of NT aacross synaptic cleft and binding to post-synaptic membrane
-activation of the postsynaptic cell
-degradation/ reuptake of the NT
What neurotransmitters are important to the process? - Answers norepinephrine, epinephrine,
dopamine, acetylcholine, serotonin and GABA
What does the Alpha 1 receptor do? - Answers vasconstriction, decrease secretions, pupil
dilation, decrease GI motility, urinary retention
What does the Alpha 2 receptor do? - Answers decrease CNS sympathetic outflow, decrease NE
release, decrease insulin release
What does the Beta 1 receptor do? - Answers ^HR, CO, automaticity, contractility, ^renin
secretion
What does the Beta 2 receptor do? - Answers bronchial relaxation, uterine relaxation,
vasodilation
What does the Dopamine receptor do? - Answers increased HR and BP
, What signs and symptoms does a patient with high sympathetic tone have? - Answers -high HR,
BP, blood glucose, alertness, air flow
-constipation, big pupil, fluid retention
What signs and symptoms does a patient with high parasympathetic tone have? - Answers low
HR, diarrhea, bowel sounds, drooling, respiratory compromise, pinpoint pupil, sweating, runny
nose
What are the actions of Epinephrine? - Answers vasoconstriction, bronchodilation, ^HR, ^glucose,
^lipolysis, GI relaxation
What is Epinephrine used for? - Answers cardiac stimulant, anaphylaxis, combined with local
anesthetics
What are the actions of Norepinephrine? - Answers ^vasoconstriction, will cause reflex,
decrease HR
What is Norepinephrine used for? - Answers septic shock
What are the actions of Dopamine? - Answers works at receptors, low doses maintain good
renal blood flow, higher doses ^BP, ^cardiac contractility
What is Dopamine used for? - Answers shock
What are the actions of Dobutamine? - Answers ^efficiency of heart beat
B1: ^HR, contractility
What is Dobutamine used for? - Answers a drug of choice for cardiac stimulation; emergency
drug
What are the actions of Phenylephrine? - Answers works on alpha receptors producing
vasoconstriction, reflex decrease HR
What is Phenlephrine used for? - Answers in cold meds, to dilate pupil
What are the actions of Terbutaline? - Answers works on beta 2 receptors to cause bronchiolar
and uterine relaxation
What is Terbutaline used for? - Answers prevent asthma and suppress premature labor and
delivery
What are actions of Mirabegron? - Answers works on the beta3 receptor in the bladder to treat
OAB, increases capacity
What is Mirabegron used for? - Answers hypertension