PC707 - FINAL EXAM (ALL MODULES)
QUESTIONS WITH COMPLETE
SOLUTIONS
What |is |prescriptive |authority? |- |CORRECT |ANSWER✔✔-Legal |right |to |prescribe |drugs
Is |the |Physicians |Desk |Reference |a |reliable |source |to |use |when |prescribing |drugs? |- |CORRECT
ANSWER✔✔-No--it |is |not |evidence-based |and |it |is |not |updated
|
What |is |the |sunshine |act? |- |CORRECT |ANSWER✔✔--part |of |the |affordable |care |act
-limits |providers |on |accepting |gifts |from |pharmaceutical |companies
-reduces |bias
What |is |pharmacology? |- |CORRECT |ANSWER✔✔--study |of |the |drugs |and |their |actions |and
|effects |on |living |things
-legal |drugs, |illegal |drugs, |prescription |drugs, |OTC |drugs
How |does |the |FDA |define |drugs |that |they |approve? |- |CORRECT |ANSWER✔✔--chemicals |that
|have |been |proved |for |safety |and |efficacy
What |must |providers |consider |when |prescribing? |- |CORRECT |ANSWER✔✔--the |dose
-the |route |of |administration
-indications
-side |effects |of |consequence
-adverse |effects
-contraindications
,-significant |drug-drug |interactions
-appropriate |monitoring |
-treatment |of |side |effects |if |necessary
What |is |pharmacokinetics? |- |CORRECT |ANSWER✔✔--how |drugs |move |in |the |body |and |what
|the |body |does |with |it
How |does |pharmacokinetics |influence |prescribing? |- |CORRECT |ANSWER✔✔--the |route
-the |dosage |needed
-dosing |intervals
What |are |the |4 |aspects |of |pharmacokinetics? |- |CORRECT |ANSWER✔✔--absorption
-distribution
-metabolism
-excretion
What |affects |bioavailability |the |most? |- |CORRECT |ANSWER✔✔-PO |administration
What |is |a |pro-drug? |- |CORRECT |ANSWER✔✔--a |drug |that |needs |to |be |metabolized |to |become
|"activated"
What |is |the |major |organ |of |metabolism? |- |CORRECT |ANSWER✔✔--Liver
-Uses |enzymes |called |"CYPs"
-these |enzymes |can |induce |or |inhibit |metabolism
,What |is |protein-binding? |- |CORRECT |ANSWER✔✔--drugs |that |have |a |high |affinity |for |proteins
|will |bind |with |them |and |therefore |become |unable |to |bind |to |receptor |sites
-in |order |to |activate |receptors |they |must |be |free |circulating |molecules
What |is |the |half-life |of |a |drug? |- |CORRECT |ANSWER✔✔--how |long |it |takes |for |a |drug |at |its
|original |amount |to |be |reduced |by |50%
Why |is |it |important |to |know |the |half-life |of |a |drug? |- |CORRECT |ANSWER✔✔--to |help
|determine |dosing |intervals |to |maintain |therapeutic |levels
What |is |the |first-pass |effect? |- |CORRECT |ANSWER✔✔--alteration |of |the |drug |dose |by
|metabolism |before |it |reaches |systemic |circulation
-only |happens |with |PO |medications
What |are |the |genetic |variances |of |metabolism? |- |CORRECT |ANSWER✔✔--poor |metabolizers
|(certain |enzymes |are |little |to |none)
-intermediate |metabolizers
-extensive |metabolizers |(NORMAL)
-ultra-rapid |metabolizers |(duplicate |genes |to |make |extra |enzymes)
What |is |the |primary |organ |of |excretion? |- |CORRECT |ANSWER✔✔-kidneys
What |are |other |methods |of |excretion? |- |CORRECT |ANSWER✔✔--saliva
-sweat
-breastmilk
-skin
-lungs
, Why |would |the |elderly |have |a |smaller |first-pass |effect? |Why |is |this |important |to |know? |-
CORRECT |ANSWER✔✔--decreased |liver |mass |
|
-decreased |enzymes
-->this |is |important |because |with |a |smaller |first |pass |effect |higher |drugs |levels |will |reach
|circulation
What |does |the |rate |of |excretion |depend |primarily |on? |- |CORRECT |ANSWER✔✔--renal |blood
|flow
-glomerular |filtration |rate
Can |side |effects |be |negative |AND |positive? |- |CORRECT |ANSWER✔✔-Yes
What |is |an |adverse |effect? |- |CORRECT |ANSWER✔✔--negative |side |effect
-undesirable
-unintended
What |are |contraindications? |- |CORRECT |ANSWER✔✔--do |not |give
-the |risks |outweigh |the |benefits
What |are |relative |contraindications? |- |CORRECT |ANSWER✔✔--the |consideration |that |there |are
|rare |exceptions |to |the |rule
-the |risk |of |NOT |taking |the |medication |potentially |is |greater |than |the |risk |of |taking |it
What |are |precautions? |- |CORRECT |ANSWER✔✔--"warnings"
-clinically |significant |
QUESTIONS WITH COMPLETE
SOLUTIONS
What |is |prescriptive |authority? |- |CORRECT |ANSWER✔✔-Legal |right |to |prescribe |drugs
Is |the |Physicians |Desk |Reference |a |reliable |source |to |use |when |prescribing |drugs? |- |CORRECT
ANSWER✔✔-No--it |is |not |evidence-based |and |it |is |not |updated
|
What |is |the |sunshine |act? |- |CORRECT |ANSWER✔✔--part |of |the |affordable |care |act
-limits |providers |on |accepting |gifts |from |pharmaceutical |companies
-reduces |bias
What |is |pharmacology? |- |CORRECT |ANSWER✔✔--study |of |the |drugs |and |their |actions |and
|effects |on |living |things
-legal |drugs, |illegal |drugs, |prescription |drugs, |OTC |drugs
How |does |the |FDA |define |drugs |that |they |approve? |- |CORRECT |ANSWER✔✔--chemicals |that
|have |been |proved |for |safety |and |efficacy
What |must |providers |consider |when |prescribing? |- |CORRECT |ANSWER✔✔--the |dose
-the |route |of |administration
-indications
-side |effects |of |consequence
-adverse |effects
-contraindications
,-significant |drug-drug |interactions
-appropriate |monitoring |
-treatment |of |side |effects |if |necessary
What |is |pharmacokinetics? |- |CORRECT |ANSWER✔✔--how |drugs |move |in |the |body |and |what
|the |body |does |with |it
How |does |pharmacokinetics |influence |prescribing? |- |CORRECT |ANSWER✔✔--the |route
-the |dosage |needed
-dosing |intervals
What |are |the |4 |aspects |of |pharmacokinetics? |- |CORRECT |ANSWER✔✔--absorption
-distribution
-metabolism
-excretion
What |affects |bioavailability |the |most? |- |CORRECT |ANSWER✔✔-PO |administration
What |is |a |pro-drug? |- |CORRECT |ANSWER✔✔--a |drug |that |needs |to |be |metabolized |to |become
|"activated"
What |is |the |major |organ |of |metabolism? |- |CORRECT |ANSWER✔✔--Liver
-Uses |enzymes |called |"CYPs"
-these |enzymes |can |induce |or |inhibit |metabolism
,What |is |protein-binding? |- |CORRECT |ANSWER✔✔--drugs |that |have |a |high |affinity |for |proteins
|will |bind |with |them |and |therefore |become |unable |to |bind |to |receptor |sites
-in |order |to |activate |receptors |they |must |be |free |circulating |molecules
What |is |the |half-life |of |a |drug? |- |CORRECT |ANSWER✔✔--how |long |it |takes |for |a |drug |at |its
|original |amount |to |be |reduced |by |50%
Why |is |it |important |to |know |the |half-life |of |a |drug? |- |CORRECT |ANSWER✔✔--to |help
|determine |dosing |intervals |to |maintain |therapeutic |levels
What |is |the |first-pass |effect? |- |CORRECT |ANSWER✔✔--alteration |of |the |drug |dose |by
|metabolism |before |it |reaches |systemic |circulation
-only |happens |with |PO |medications
What |are |the |genetic |variances |of |metabolism? |- |CORRECT |ANSWER✔✔--poor |metabolizers
|(certain |enzymes |are |little |to |none)
-intermediate |metabolizers
-extensive |metabolizers |(NORMAL)
-ultra-rapid |metabolizers |(duplicate |genes |to |make |extra |enzymes)
What |is |the |primary |organ |of |excretion? |- |CORRECT |ANSWER✔✔-kidneys
What |are |other |methods |of |excretion? |- |CORRECT |ANSWER✔✔--saliva
-sweat
-breastmilk
-skin
-lungs
, Why |would |the |elderly |have |a |smaller |first-pass |effect? |Why |is |this |important |to |know? |-
CORRECT |ANSWER✔✔--decreased |liver |mass |
|
-decreased |enzymes
-->this |is |important |because |with |a |smaller |first |pass |effect |higher |drugs |levels |will |reach
|circulation
What |does |the |rate |of |excretion |depend |primarily |on? |- |CORRECT |ANSWER✔✔--renal |blood
|flow
-glomerular |filtration |rate
Can |side |effects |be |negative |AND |positive? |- |CORRECT |ANSWER✔✔-Yes
What |is |an |adverse |effect? |- |CORRECT |ANSWER✔✔--negative |side |effect
-undesirable
-unintended
What |are |contraindications? |- |CORRECT |ANSWER✔✔--do |not |give
-the |risks |outweigh |the |benefits
What |are |relative |contraindications? |- |CORRECT |ANSWER✔✔--the |consideration |that |there |are
|rare |exceptions |to |the |rule
-the |risk |of |NOT |taking |the |medication |potentially |is |greater |than |the |risk |of |taking |it
What |are |precautions? |- |CORRECT |ANSWER✔✔--"warnings"
-clinically |significant |
