STEP 1 USMLE REVIEW with Verified Answers Graded A+
often precedes squamous cell carcinoma - anti-IgG antibodies - diagnosis? -
ANSWER -actinic keratosis ANSWER -rheumatoid arthritis
primary adrenocortical deficiency - antimitochondrial antibodies - diagnosis? -
ANSWER -Addison's disease ANSWER -primary biliary cirrhosis
polyostotic fibrous dysplasia, precocious puberty, antineutrophil antibodies - diagnosis? -
cafe-au-lait spots, short stature, young girls - ANSWER -vasculitis
diagnosis? - ANSWER -Albright's
syndrome
antiplatelet antibodies - diagnosis? -
ANSWER -idiopathic thrombocytopenic
hereditary nephritis with nerve deafness - purpura
ANSWER -Alport's syndrome
arachnodactyly - diagnosis? - ANSWER -
anti-basement membrane antibodies - Marfan's syndrome
diagnosis? - ANSWER -Goodpasture's
syndrome
Argyll-Robertson pupil - diagnosis? -
ANSWER -neurosyphilis
anticentromere antibodies - diagnosis? -
ANSWER -scleroderma (CREST)
Arnold-Chiari malformation - ANSWER -
cerebellar tonsillar herniation
anti-double-stranded DNA antibodies (ANA
antibodies) - diagnosis?
- what hypersensitivity type? - ANSWER - Aschoff bodies - diagnosis? - ANSWER -
SLE - type III hypersensitivity rheumatic fever
anti-epithelial cell antibodies - diagnosis? - atrophy of the mammillary bodies - diagnosis? -
ANSWER -pemphigus vulgaris ANSWER -Wernicke's encephalopathy
antigliadin antibodies - diagnosis? - Auer rods - diagnosis? - ANSWER -acute
ANSWER -celiac disease myelogenous leukemia (especially promyelocytic
type)
antihistone antibodies - diagnosis? -
ANSWER -drug-induced SLE autosplenectomy - diagnosis? - ANSWER -
sickle cell anemia
,STEP 1 USMLE REVIEW with Verified Answers Graded A+
bloody tap on LP - diagnosis? - ANSWER -
Babinski's sign is associated with what? - subarachnoid hemorrhage
ANSWER -UMN lesion
"blue bloater" - ANSWER -chronic
"bamboo spine" on x-ray - ANSWER - bronchitis
ankylosing spondylitis
blue-domed cysts - diagnosis? - ANSWER -
basophilic stippling of RBCs - diagnosis? - fibrocystic change of the breast
ANSWER -lead poisoning
blue sclera - diagnosis? - ANSWER -
defective dystrophin, less severe than osteogenesis imperfecta
Duchenne's - ANSWER -Becker's muscular
dystrophy
boot-shaped heart on x-ray - possible diagnoses?
- ANSWER -tetralogy of Fallot or RVH
LMN CN VII palsy - ANSWER -Bell's palsy
Bouchard's nodes - diagnosis?
Bence Jones proteins - possible diagnoses? - where are they located?
- in each case, what are the proteins? - - why do they occur? - ANSWER -
ANSWER -multiple myeloma - kappa or osteoarthritis - on PIP secondary to osteophytes
lambda light chains
Waldenstrom's macroglobulinemia - IgM
boutonniere deformity - diagnosis? -
ANSWER -rheumatoid arthritis
IgA nephropathy - diagnosis? - ANSWER -
Berger's disease
branching rods in oral infection - diagnosis? -
ANSWER -Actinomyces israelii
Bernard-Soulier disease - what is the defect? -
ANSWER -defect in platelet adhesion
"brown tumor" of bone - possible diagnoses?
- what causes the brown color? -
bilateral hilar adenopathy, uveitis - diagnosis? - ANSWER -hyperparathyroidism or osteitis
ANSWER -sarcoidosis fibrosa cystica (von Recklinghausen's disease)
- color is due to hemorrhage in cysts
Birbeck granules on EM - diagnosis? -
ANSWER -histiocytosis X (eosinophilic X-linked agammaglobulinemia - ANSWER -
granuloma) Bruton's disease
,STEP 1 USMLE REVIEW with Verified Answers Graded A+
posthepatic venous thrombosis - diagnosis? - trypanosome infection - diagnosis? -
ANSWER -Budd-Chiari syndrome ANSWER -Chagas' disease
Buerger's disease - what size arteries does it painless chancre - diagnosis? - ANSWER -
affect? - ANSWER -small or medium-artery primary syphilis
vasculitis
painful chancroid - cause? - ANSWER -
Burkitt's lymphoma - what is the translocation? Haemophilus ducreyi
- what virus is it associated with?
- appearance on histology? - ANSWER -
8:14 translocation Charcot's triad of multiple sclerosis -
EBV ANSWER -nystagmus, intention tremor,
starry sky appearance scanning speech
Burton's lines - diagnosis? - ANSWER - Charcot's triad of cholangitis - ANSWER -
lead poisoning jaundice, RUQ pain, fever
what types of ANCA are associated with Charcot-Leyden crystals - diagnosis?
Wegener's granulomatosis and microscopic - what are they? - ANSWER -bronchial
polyangiitis? - ANSWER -Wegener's - c- asthma - eosinophil membranes
ANCA
MPA - p-ANCA
what is the defect in Chediak-Higashi disease? -
ANSWER -phagocyte deficiency
cafe-au-lait spots on skin - diagnosis? -
ANSWER -neurofibromatosis
cherry-red spot on macula - possible diagnoses?
- ANSWER -Tay-Sachs or Niemann-Pick
calf pseudohypertrophy - diagnosis? - disease
ANSWER -Duchenne's muscular dystrophy
what are Cheyne-Stokes respirations, and in
Call-Exner bodies - diagnosis? - what circumstance do they occur? -
ANSWER -granulosa-theca cell tumor of ANSWER -central apnea in CHF and
the ovary increased intracranial pressure
cardiomegaly with apical atrophy - diagnosis? - "chocolate cysts" - ANSWER -
ANSWER -Chagas' disease endometriosis
, STEP 1 USMLE REVIEW with Verified Answers Graded A+
what does chronic atrophic gastritis predispose
to? - ANSWER -gastric carcinoma
Councilman bodies - diagnosis? -
ANSWER -toxic or viral hepatitis
Chvostek's sign - what is it, and what does it
indicate? - ANSWER -facial muscle spasm
upon tapping - sign of hypocalcemia Cowdry type A bodies - caused by what? -
ANSWER -herpesvirus
DES exposure in utero predisposes to what? -
ANSWER -clear cell adenocarcinoma of crescents in Bowman's capsule - diagnosis? -
the vagina ANSWER -rapidly progressive crescentic
glomerulonephritis
clue cells - diagnosis? - ANSWER -
Gardnerella vaginitis what is Crigler-Najjar syndrome? -
ANSWER -congenital unconjugated
hyperbilirubinemia - due to absent UDP
Codman's triangle on x-ray - diagnosis? - glucuronyl transferase
ANSWER -osteosarcoma
acute gastric ulcer associated with severe burns -
cold agglutinins - possible diagnoses? - ANSWER -Curling's ulcer
ANSWER -Mycoplasma pneumonia or
infectious mononucleosis
currant-jelly sputum - diagnosis? -
ANSWER -Klebsiella
cold intolerance - sign of what? -
ANSWER -hypothyroidism
Curschmann's spirals - diagnosis?
- what are they? - ANSWER -bronchial
condylomata lata - diagnosis? - ANSWER - asthma - whorled mucous plugs
secondary syphilis
acute gastric ulcer associated with CNS injury -
continuous machinery murmur - indicates what? - ANSWER -Cushing's ulcer
ANSWER -patent ductus arteriosus
D-dimers - diagnosis? - ANSWER -DIC
what is the defect in Cori's disease? -
ANSWER -debranching enzyme deficiency
depigmentation of neurons in substantia nigra -
diagnosis?
cough, conjunctivitis, coryza, fever - diagnosis? - - where is the defect?
ANSWER -measles - symptoms? - ANSWER -Parkinson's
often precedes squamous cell carcinoma - anti-IgG antibodies - diagnosis? -
ANSWER -actinic keratosis ANSWER -rheumatoid arthritis
primary adrenocortical deficiency - antimitochondrial antibodies - diagnosis? -
ANSWER -Addison's disease ANSWER -primary biliary cirrhosis
polyostotic fibrous dysplasia, precocious puberty, antineutrophil antibodies - diagnosis? -
cafe-au-lait spots, short stature, young girls - ANSWER -vasculitis
diagnosis? - ANSWER -Albright's
syndrome
antiplatelet antibodies - diagnosis? -
ANSWER -idiopathic thrombocytopenic
hereditary nephritis with nerve deafness - purpura
ANSWER -Alport's syndrome
arachnodactyly - diagnosis? - ANSWER -
anti-basement membrane antibodies - Marfan's syndrome
diagnosis? - ANSWER -Goodpasture's
syndrome
Argyll-Robertson pupil - diagnosis? -
ANSWER -neurosyphilis
anticentromere antibodies - diagnosis? -
ANSWER -scleroderma (CREST)
Arnold-Chiari malformation - ANSWER -
cerebellar tonsillar herniation
anti-double-stranded DNA antibodies (ANA
antibodies) - diagnosis?
- what hypersensitivity type? - ANSWER - Aschoff bodies - diagnosis? - ANSWER -
SLE - type III hypersensitivity rheumatic fever
anti-epithelial cell antibodies - diagnosis? - atrophy of the mammillary bodies - diagnosis? -
ANSWER -pemphigus vulgaris ANSWER -Wernicke's encephalopathy
antigliadin antibodies - diagnosis? - Auer rods - diagnosis? - ANSWER -acute
ANSWER -celiac disease myelogenous leukemia (especially promyelocytic
type)
antihistone antibodies - diagnosis? -
ANSWER -drug-induced SLE autosplenectomy - diagnosis? - ANSWER -
sickle cell anemia
,STEP 1 USMLE REVIEW with Verified Answers Graded A+
bloody tap on LP - diagnosis? - ANSWER -
Babinski's sign is associated with what? - subarachnoid hemorrhage
ANSWER -UMN lesion
"blue bloater" - ANSWER -chronic
"bamboo spine" on x-ray - ANSWER - bronchitis
ankylosing spondylitis
blue-domed cysts - diagnosis? - ANSWER -
basophilic stippling of RBCs - diagnosis? - fibrocystic change of the breast
ANSWER -lead poisoning
blue sclera - diagnosis? - ANSWER -
defective dystrophin, less severe than osteogenesis imperfecta
Duchenne's - ANSWER -Becker's muscular
dystrophy
boot-shaped heart on x-ray - possible diagnoses?
- ANSWER -tetralogy of Fallot or RVH
LMN CN VII palsy - ANSWER -Bell's palsy
Bouchard's nodes - diagnosis?
Bence Jones proteins - possible diagnoses? - where are they located?
- in each case, what are the proteins? - - why do they occur? - ANSWER -
ANSWER -multiple myeloma - kappa or osteoarthritis - on PIP secondary to osteophytes
lambda light chains
Waldenstrom's macroglobulinemia - IgM
boutonniere deformity - diagnosis? -
ANSWER -rheumatoid arthritis
IgA nephropathy - diagnosis? - ANSWER -
Berger's disease
branching rods in oral infection - diagnosis? -
ANSWER -Actinomyces israelii
Bernard-Soulier disease - what is the defect? -
ANSWER -defect in platelet adhesion
"brown tumor" of bone - possible diagnoses?
- what causes the brown color? -
bilateral hilar adenopathy, uveitis - diagnosis? - ANSWER -hyperparathyroidism or osteitis
ANSWER -sarcoidosis fibrosa cystica (von Recklinghausen's disease)
- color is due to hemorrhage in cysts
Birbeck granules on EM - diagnosis? -
ANSWER -histiocytosis X (eosinophilic X-linked agammaglobulinemia - ANSWER -
granuloma) Bruton's disease
,STEP 1 USMLE REVIEW with Verified Answers Graded A+
posthepatic venous thrombosis - diagnosis? - trypanosome infection - diagnosis? -
ANSWER -Budd-Chiari syndrome ANSWER -Chagas' disease
Buerger's disease - what size arteries does it painless chancre - diagnosis? - ANSWER -
affect? - ANSWER -small or medium-artery primary syphilis
vasculitis
painful chancroid - cause? - ANSWER -
Burkitt's lymphoma - what is the translocation? Haemophilus ducreyi
- what virus is it associated with?
- appearance on histology? - ANSWER -
8:14 translocation Charcot's triad of multiple sclerosis -
EBV ANSWER -nystagmus, intention tremor,
starry sky appearance scanning speech
Burton's lines - diagnosis? - ANSWER - Charcot's triad of cholangitis - ANSWER -
lead poisoning jaundice, RUQ pain, fever
what types of ANCA are associated with Charcot-Leyden crystals - diagnosis?
Wegener's granulomatosis and microscopic - what are they? - ANSWER -bronchial
polyangiitis? - ANSWER -Wegener's - c- asthma - eosinophil membranes
ANCA
MPA - p-ANCA
what is the defect in Chediak-Higashi disease? -
ANSWER -phagocyte deficiency
cafe-au-lait spots on skin - diagnosis? -
ANSWER -neurofibromatosis
cherry-red spot on macula - possible diagnoses?
- ANSWER -Tay-Sachs or Niemann-Pick
calf pseudohypertrophy - diagnosis? - disease
ANSWER -Duchenne's muscular dystrophy
what are Cheyne-Stokes respirations, and in
Call-Exner bodies - diagnosis? - what circumstance do they occur? -
ANSWER -granulosa-theca cell tumor of ANSWER -central apnea in CHF and
the ovary increased intracranial pressure
cardiomegaly with apical atrophy - diagnosis? - "chocolate cysts" - ANSWER -
ANSWER -Chagas' disease endometriosis
, STEP 1 USMLE REVIEW with Verified Answers Graded A+
what does chronic atrophic gastritis predispose
to? - ANSWER -gastric carcinoma
Councilman bodies - diagnosis? -
ANSWER -toxic or viral hepatitis
Chvostek's sign - what is it, and what does it
indicate? - ANSWER -facial muscle spasm
upon tapping - sign of hypocalcemia Cowdry type A bodies - caused by what? -
ANSWER -herpesvirus
DES exposure in utero predisposes to what? -
ANSWER -clear cell adenocarcinoma of crescents in Bowman's capsule - diagnosis? -
the vagina ANSWER -rapidly progressive crescentic
glomerulonephritis
clue cells - diagnosis? - ANSWER -
Gardnerella vaginitis what is Crigler-Najjar syndrome? -
ANSWER -congenital unconjugated
hyperbilirubinemia - due to absent UDP
Codman's triangle on x-ray - diagnosis? - glucuronyl transferase
ANSWER -osteosarcoma
acute gastric ulcer associated with severe burns -
cold agglutinins - possible diagnoses? - ANSWER -Curling's ulcer
ANSWER -Mycoplasma pneumonia or
infectious mononucleosis
currant-jelly sputum - diagnosis? -
ANSWER -Klebsiella
cold intolerance - sign of what? -
ANSWER -hypothyroidism
Curschmann's spirals - diagnosis?
- what are they? - ANSWER -bronchial
condylomata lata - diagnosis? - ANSWER - asthma - whorled mucous plugs
secondary syphilis
acute gastric ulcer associated with CNS injury -
continuous machinery murmur - indicates what? - ANSWER -Cushing's ulcer
ANSWER -patent ductus arteriosus
D-dimers - diagnosis? - ANSWER -DIC
what is the defect in Cori's disease? -
ANSWER -debranching enzyme deficiency
depigmentation of neurons in substantia nigra -
diagnosis?
cough, conjunctivitis, coryza, fever - diagnosis? - - where is the defect?
ANSWER -measles - symptoms? - ANSWER -Parkinson's
