"MCB 252: COMPREHENSIVE CELL BIOLOGY
EVALUATION"
A. Yes, latrunculin would stop phagocytosis. - answers✔✔1. In lecture we discussed the fact
that actin plays a role in phagocytosis. Based on that discussion, do you expect that addition of
latrunculin to cells would stop phagocytosis? (2pts)
A. Yes, latrunculin would stop phagocytosis.
B. No, latrunculin would not stop phagocytosis.
B. FALSE - answers✔✔2. As discussed in lecture, the contractile bundles (sarcomeres) found in
muscle cells most likely appeared in evolution before the contractile bundles found in stress
fibers. (2pts)
A. TRUE
B. FALSE
A. TRUE - answers✔✔Intermediate filaments are considered equilibrium polymers, as opposed
to actin filaments which are best described as steady state filaments. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔4. As described in lecture, because actin filaments are helical, any motor
protein that moves along those filaments must follow a helical path. (2pts)
A. TRUE
,B. FALSE
A. TRUE - answers✔✔5. As described in lecture, a polyclonal antibody contains many different
antibodies, each of which recognizes a distinct epitope on the surface of an antigen. (2pts)
A. TRUE
B. FALSE
A. The plus end - answers✔✔6. Profilin binds to which end of an actin monomer? (2pts)
A. The plus end
B. The minus end
A. TRUE - answers✔✔7. Exon shuffling occurs at the level of DNA in the genome; whereas,
splicing occurs at the level of RNA. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔8. As described in lecture, Homo sapiens migrated out of Africa before
Neanderthals migrated out of Africa. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔9. In lecture, we discussed the modular construction of some genes and
the evolution of genes (and proteins) by the addition of domains. As described in lecture, this
process occurs in prokaryotes and eukaryotes. (2pts)
A. TRUE
B. FALSE
, A. TRUE - answers✔✔10. As described in lecture, all cytoskeletal polymers are multi-stranded.
(2pts)
A. TRUE
B. FALSE
D. That enhancers can act over long distances - answers✔✔11. Which property of eukaryotic
gene regulatory regions, as discussed in lecture, allowed for the evolution complex regulatory
regions? (3pts)
A. That core promoters act over precise distances
B. That there are different types of core promoters
C. That eukaryotic genes have a regulatory promoter
D. That enhancers can act over long distances
E. Both A and B are correct.
C. i is FALSE, and ii is TRUE. - answers✔✔12. Which of the following statements is/are TRUE, and
which is/are FALSE?
i = The majority of different colors of fluorescent proteins used by cell biologist are all naturally
occurring proteins that were isolated from different types of aquatic organisms.
ii = As described in lecture, when purifying a protein of interest one needs an assay that is
specific for that particular protein. (3pts)
A. Both i and ii are TRUE.
B. i is TRUE, and ii is FALSE.
C. i is FALSE, and ii is TRUE.
D. Both i and ii are FALSE.
B. The minus end of the actin filament is moving away from you. - answers✔✔13.
Congratulations! You finally managed to build a ray gun that allows you to shrink yourself down
to the size of a molecule. Like any normal person, your first idea is to stand on top of a formin
EVALUATION"
A. Yes, latrunculin would stop phagocytosis. - answers✔✔1. In lecture we discussed the fact
that actin plays a role in phagocytosis. Based on that discussion, do you expect that addition of
latrunculin to cells would stop phagocytosis? (2pts)
A. Yes, latrunculin would stop phagocytosis.
B. No, latrunculin would not stop phagocytosis.
B. FALSE - answers✔✔2. As discussed in lecture, the contractile bundles (sarcomeres) found in
muscle cells most likely appeared in evolution before the contractile bundles found in stress
fibers. (2pts)
A. TRUE
B. FALSE
A. TRUE - answers✔✔Intermediate filaments are considered equilibrium polymers, as opposed
to actin filaments which are best described as steady state filaments. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔4. As described in lecture, because actin filaments are helical, any motor
protein that moves along those filaments must follow a helical path. (2pts)
A. TRUE
,B. FALSE
A. TRUE - answers✔✔5. As described in lecture, a polyclonal antibody contains many different
antibodies, each of which recognizes a distinct epitope on the surface of an antigen. (2pts)
A. TRUE
B. FALSE
A. The plus end - answers✔✔6. Profilin binds to which end of an actin monomer? (2pts)
A. The plus end
B. The minus end
A. TRUE - answers✔✔7. Exon shuffling occurs at the level of DNA in the genome; whereas,
splicing occurs at the level of RNA. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔8. As described in lecture, Homo sapiens migrated out of Africa before
Neanderthals migrated out of Africa. (2pts)
A. TRUE
B. FALSE
B. FALSE - answers✔✔9. In lecture, we discussed the modular construction of some genes and
the evolution of genes (and proteins) by the addition of domains. As described in lecture, this
process occurs in prokaryotes and eukaryotes. (2pts)
A. TRUE
B. FALSE
, A. TRUE - answers✔✔10. As described in lecture, all cytoskeletal polymers are multi-stranded.
(2pts)
A. TRUE
B. FALSE
D. That enhancers can act over long distances - answers✔✔11. Which property of eukaryotic
gene regulatory regions, as discussed in lecture, allowed for the evolution complex regulatory
regions? (3pts)
A. That core promoters act over precise distances
B. That there are different types of core promoters
C. That eukaryotic genes have a regulatory promoter
D. That enhancers can act over long distances
E. Both A and B are correct.
C. i is FALSE, and ii is TRUE. - answers✔✔12. Which of the following statements is/are TRUE, and
which is/are FALSE?
i = The majority of different colors of fluorescent proteins used by cell biologist are all naturally
occurring proteins that were isolated from different types of aquatic organisms.
ii = As described in lecture, when purifying a protein of interest one needs an assay that is
specific for that particular protein. (3pts)
A. Both i and ii are TRUE.
B. i is TRUE, and ii is FALSE.
C. i is FALSE, and ii is TRUE.
D. Both i and ii are FALSE.
B. The minus end of the actin filament is moving away from you. - answers✔✔13.
Congratulations! You finally managed to build a ray gun that allows you to shrink yourself down
to the size of a molecule. Like any normal person, your first idea is to stand on top of a formin
