Glomerular disease
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Nephrotic or nephritic
Can lead to AKI and slowly turns into CKD if unnoticed
,Metabolic acidosis
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pH<7.35 and bicarbonate<22
-loss of bicarbonate
-increase of metabolic/nonvolatile acids
-decrease in acid excretion
characterized by normal anion gap or elevated anion gap
Calculation of water deficit
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Liters of water to be given = Ideal total body water - current total body
water
AKI Clinical Course: Diuretic Phase
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Lasts 1-2 weeks, kidney function improves with significant water and
electrolyte losses due to dysfunctional reabsorption, GFR increases while
renal tubular function lags due to scarring and edema
What is the characteristic of Type 1 Distal RTA?
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Decrease in distal nephron to produce new bicarbonate, resulting in
hypokalemia
Outcomes
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Cure, remission, chronicity, or death
-not specifically treatment
Normal body fluid osmolality
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280-294 mOsm/kg
Stage 5 CKD
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, End stage kidney disease, kidney failure
GFR<15
Albuminuria 30-300 A3>300
Uremia, severe hypertension, hyperphosphatemia, anemia
Anion gap
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Difference between total cations in ECF and total anions in ECF
Normal: 10-14
Anion gap = Na - (Cl+HCO3)
Calculation of ideal total body water in water excess
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1 - (Na/125)
What is bilirubin?
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Nephrotic or nephritic
Can lead to AKI and slowly turns into CKD if unnoticed
,Metabolic acidosis
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pH<7.35 and bicarbonate<22
-loss of bicarbonate
-increase of metabolic/nonvolatile acids
-decrease in acid excretion
characterized by normal anion gap or elevated anion gap
Calculation of water deficit
Give this one a try later!
Liters of water to be given = Ideal total body water - current total body
water
AKI Clinical Course: Diuretic Phase
Give this one a try later!
Lasts 1-2 weeks, kidney function improves with significant water and
electrolyte losses due to dysfunctional reabsorption, GFR increases while
renal tubular function lags due to scarring and edema
What is the characteristic of Type 1 Distal RTA?
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Decrease in distal nephron to produce new bicarbonate, resulting in
hypokalemia
Outcomes
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Cure, remission, chronicity, or death
-not specifically treatment
Normal body fluid osmolality
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280-294 mOsm/kg
Stage 5 CKD
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, End stage kidney disease, kidney failure
GFR<15
Albuminuria 30-300 A3>300
Uremia, severe hypertension, hyperphosphatemia, anemia
Anion gap
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Difference between total cations in ECF and total anions in ECF
Normal: 10-14
Anion gap = Na - (Cl+HCO3)
Calculation of ideal total body water in water excess
Give this one a try later!
1 - (Na/125)
What is bilirubin?
Give this one a try later!
