ATI Pharmacology RN Questions &
Correct Answers
Chloroquine phosphate (Aralen): Indication - ANSWER-malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - ANSWER-w/alteplase for acute MI
Warfarin (Coumadin) Use - ANSWER-long-term prophylaxis of thrombosis [antidote—
Vit K]
Clopidogrel (Plavix) Use - ANSWER-reduce long-term risk of clotting w/ atherosclerosis
and recent MI of CVA
Alteplase (Activase) [antithrombolytic] Use - ANSWER-Acute MI/CVA (has short half-
life)
Methylphenidate (Concerta) Use - ANSWER-marcolepsy Precaution: avoid caffeine use
Testosterone IM use - ANSWER-If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - ANSWER-With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - ANSWER-anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - ANSWER-bulk-forming agent with minimal Side Effects
(SE)
Psyllium (Metamucil) use - ANSWER-bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - ANSWER-edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - ANSWER-Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
, Norgestrel (Ovrette) use and contraindication - ANSWER-contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
IM injection site - ANSWER-locate dorsogluteal site
Nausea tx - ANSWER-antiemetic plus cool, damp cloth to forehead, neck, and wrists.
Allopurinol (Zyloprim) indication - ANSWER-Gout; MofA: ↓ serum uric acid levels &
urinary uric acid secretion; Precaution: avoid foods that acidify urine such as corn
TB—multi drug tx - ANSWER-Isoniazid(INH), Rifampin, pyrazinamide, ethambutol—to
deal w/ resistant strains
ACE Inhib. Lisinopril (Zestril) SE - ANSWER-dry/persistent cough for 1-2 wks from ↑
bradykinin
Furosemide (Lasix) [loop diuretic] Intervention - ANSWER-check BP before giving to
determine baseline; can cause ↓ BP by ↓ circulatory volume or by relaxing venous
smooth muscle
Ticlopidine (Ticlid) indication - ANSWER-prevent coronary artery thombosis;
Intervention: check platelet count
What intervention needs to be preformed before giving an IV medications - ANSWER-
assess site for redness/swelling before administration
Collagenase (Santy) use - ANSWER-Debride ulcers
Interferon Use - ANSWER-Prevent viral replication
Isotretinoin (Accutane) contraindication - ANSWER-pregnancy w/ 2 forms of birth
control due to teratogenic effects
Epoetin Alfa (Procrit) indication - ANSWER-treat anemia; SE: headache, HTN, seizures
RT Hct rises too quickly
Urofollitropin (Fertinex) side effect - ANSWER-ovarian hyperstimulation syndrome.
Hypertensive crisis S/S - ANSWER-flushed skin, headache, visual changes
Acetylcysteine (Mucomyst) indication - ANSWER-prevent liver damage following
acetaminophen (Tylenol) overdose. Most effective if given shortly after ingestion; some
protection up to 24 hrs.
Correct Answers
Chloroquine phosphate (Aralen): Indication - ANSWER-malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - ANSWER-w/alteplase for acute MI
Warfarin (Coumadin) Use - ANSWER-long-term prophylaxis of thrombosis [antidote—
Vit K]
Clopidogrel (Plavix) Use - ANSWER-reduce long-term risk of clotting w/ atherosclerosis
and recent MI of CVA
Alteplase (Activase) [antithrombolytic] Use - ANSWER-Acute MI/CVA (has short half-
life)
Methylphenidate (Concerta) Use - ANSWER-marcolepsy Precaution: avoid caffeine use
Testosterone IM use - ANSWER-If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - ANSWER-With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - ANSWER-anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - ANSWER-bulk-forming agent with minimal Side Effects
(SE)
Psyllium (Metamucil) use - ANSWER-bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - ANSWER-edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - ANSWER-Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
, Norgestrel (Ovrette) use and contraindication - ANSWER-contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
IM injection site - ANSWER-locate dorsogluteal site
Nausea tx - ANSWER-antiemetic plus cool, damp cloth to forehead, neck, and wrists.
Allopurinol (Zyloprim) indication - ANSWER-Gout; MofA: ↓ serum uric acid levels &
urinary uric acid secretion; Precaution: avoid foods that acidify urine such as corn
TB—multi drug tx - ANSWER-Isoniazid(INH), Rifampin, pyrazinamide, ethambutol—to
deal w/ resistant strains
ACE Inhib. Lisinopril (Zestril) SE - ANSWER-dry/persistent cough for 1-2 wks from ↑
bradykinin
Furosemide (Lasix) [loop diuretic] Intervention - ANSWER-check BP before giving to
determine baseline; can cause ↓ BP by ↓ circulatory volume or by relaxing venous
smooth muscle
Ticlopidine (Ticlid) indication - ANSWER-prevent coronary artery thombosis;
Intervention: check platelet count
What intervention needs to be preformed before giving an IV medications - ANSWER-
assess site for redness/swelling before administration
Collagenase (Santy) use - ANSWER-Debride ulcers
Interferon Use - ANSWER-Prevent viral replication
Isotretinoin (Accutane) contraindication - ANSWER-pregnancy w/ 2 forms of birth
control due to teratogenic effects
Epoetin Alfa (Procrit) indication - ANSWER-treat anemia; SE: headache, HTN, seizures
RT Hct rises too quickly
Urofollitropin (Fertinex) side effect - ANSWER-ovarian hyperstimulation syndrome.
Hypertensive crisis S/S - ANSWER-flushed skin, headache, visual changes
Acetylcysteine (Mucomyst) indication - ANSWER-prevent liver damage following
acetaminophen (Tylenol) overdose. Most effective if given shortly after ingestion; some
protection up to 24 hrs.
