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KU Biol 600 Test 2 2025/2026 Exam
Questions and Answers 100%
Guaranteed Success | Already Rated A+
What is heme made of? - 🧠 ANSWER ✔✔porphyrin ring and Fe2+ (or Fe3+)
The function of this protein is to store oxygen in muscle cells - 🧠 ANSWER
✔✔myoglobin
This type of binding is indicated by a sigmoidal-shaped binding curve. - 🧠
ANSWER ✔✔cooperative
What is the oxidation state of iron in deoxyhemoglobin?
In oxyhemoglobin? - 🧠 ANSWER ✔✔Fe2+
Fe3+
How is heme bound to the polypeptide of hemoglobin? - 🧠 ANSWER ✔✔proximal
histidine forms a metal coordination bond with the iron of heme
Upon binding O2, what happens to the shape of the heme? - 🧠 ANSWER ✔✔it
flattens
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STATEMENT. ALL RIGHTS RESERVED
, 2
How is O2 binding to one Hb subunit transmitted to the other Hb subunits? - 🧠
ANSWER ✔✔Upon O2-binding, the shape of the heme flattens, which shifts the
position of the proximal histidine. This effect is transmitted to the alpha-helix
where the proximal histidine is, and eventually to the other Hb subunits.
Why does the binding of 2,3-bisphosphogycerate to hemoglobin
(increase,decrease) its affinity to oxygen? - 🧠 ANSWER ✔✔2,3-BPG binds to, and
stabilizes the deoxy form of Hb
What residues in hemoglobin are involved in binding 2,3-BPG? - 🧠 ANSWER
✔✔2,3-BPG is negatively charged; it binds to His and Lys residues, which are
positively charged
Lower pH will (increase/decrease) the oxygen-binding of hemoglobin. This is
known as the _________. - 🧠 ANSWER ✔✔decrease
Bohr effect
Carbon dioxide will (increase/decrease) pH and (increase/decrease) O2-binding
affinity of Hb. - 🧠 ANSWER ✔✔decrease
decrease
2
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
KU Biol 600 Test 2 2025/2026 Exam
Questions and Answers 100%
Guaranteed Success | Already Rated A+
What is heme made of? - 🧠 ANSWER ✔✔porphyrin ring and Fe2+ (or Fe3+)
The function of this protein is to store oxygen in muscle cells - 🧠 ANSWER
✔✔myoglobin
This type of binding is indicated by a sigmoidal-shaped binding curve. - 🧠
ANSWER ✔✔cooperative
What is the oxidation state of iron in deoxyhemoglobin?
In oxyhemoglobin? - 🧠 ANSWER ✔✔Fe2+
Fe3+
How is heme bound to the polypeptide of hemoglobin? - 🧠 ANSWER ✔✔proximal
histidine forms a metal coordination bond with the iron of heme
Upon binding O2, what happens to the shape of the heme? - 🧠 ANSWER ✔✔it
flattens
1
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, 2
How is O2 binding to one Hb subunit transmitted to the other Hb subunits? - 🧠
ANSWER ✔✔Upon O2-binding, the shape of the heme flattens, which shifts the
position of the proximal histidine. This effect is transmitted to the alpha-helix
where the proximal histidine is, and eventually to the other Hb subunits.
Why does the binding of 2,3-bisphosphogycerate to hemoglobin
(increase,decrease) its affinity to oxygen? - 🧠 ANSWER ✔✔2,3-BPG binds to, and
stabilizes the deoxy form of Hb
What residues in hemoglobin are involved in binding 2,3-BPG? - 🧠 ANSWER
✔✔2,3-BPG is negatively charged; it binds to His and Lys residues, which are
positively charged
Lower pH will (increase/decrease) the oxygen-binding of hemoglobin. This is
known as the _________. - 🧠 ANSWER ✔✔decrease
Bohr effect
Carbon dioxide will (increase/decrease) pH and (increase/decrease) O2-binding
affinity of Hb. - 🧠 ANSWER ✔✔decrease
decrease
2
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
