Which two processes are involved in platelet activation?
Cyclooxygenase-1 (COX-1) inactivation
Aggregation
Adhesion correct answers Platelet activation involves three linked processes: (1) adhesion, (2)
activation, and (3) aggregation. Platelet activation stimuli include epinephrine, thrombin, and
collagen.
Select four common causes of anemia from the list below.
Increased red cell destruction
Chronic blood loss
Severe bleeding
Impaired erythrocyte production
Blood transfusion correct answers Impaired production of erythrocytes, increased red cell
destruction, severe bleeding, and chronic blood loss can cause anemia.
explain why the nurse practitioner should ask the patient about her paresthesias and ataxia.
correct answers Without the presence of intrinsic factor, vitamin B12 will not be absorbed
effectively from the gastrointestinal tract.
Describe what causes pernicious anemia. correct answers Pernicious anemia is caused by vitamin
B12 deficiency, which is often associated with the end stage of type A chronic atrophic
(autoimmune) gastritis. Autoimmune gastritis impairs the production of IF, which is required for
vitamin B12 uptake from the gut.
Select three possible causes of lymphadenopathy from the options below.
Inflammatory condition
Lipid storage disease
Neoplastic disease
, Cardiac disease
Peripheral vascular dysfunction correct answers There are multiple causes of lymphadenopathy.
It may be caused by neoplastic disease, so all lymphadenopathies must be closely followed and
evaluated. Lymphadenopathy may also be caused by an immunologic or inflammatory condition
and by lipid storage disease; this type of lymphadenopathy is usually widespread, including the
liver and spleen.
What is the most common cause of iron deficiency anemia (IDA) in children during the first few
years of life?
Dietary insufficiencies
Absorption problems
Blood loss
Increased iron requirement correct answers Insufficient dietary iron is the most common cause of
IDA in children during the first few years of life.
Which stressor triggers sickling?
Increased plasma volume
Increased oxygen tension of the blood
Decreased plasma osmolality
Low temperature correct answers Low temperature causes vasoconstriction, slowing blood flow,
leading to RBC deoxygenation, which triggers sickling.
cause of ITP correct answers In 70% of ITP cases, there is an antecedent viral disease that
stimulates production of antiplatelet antibodies that bind to the plasma membranes of platelets,
causing platelet sequestration and destruction by phagocytes in the spleen and other lymphoid
tissues at a rate that exceeds the ability of the bone marrow to produce them.
What is the likelihood that the patient will recover? with ITP correct answers The prognosis is
excellent; 75% of children recover completely within three months. By six months after onset,
80% of affected children have regained normal platelet counts.