NUR 521 Advanced Pharmacology – complete Exam 4 Blueprint TEST BANK Practice Questions with correct answers and Rationale 2025 University of Alabama

NUR 521: Advanced Pharmacology – complete Exam 4 Blueprint TEST BANK Practice Questions with correct answers and Rationale 2025 University of Alabama Section 1: Basic Questions About Antifungals Question 1 Which of the following is an opportunistic systemic fungal infection? • A) Sporotrichosis • B) Aspergillosis • C) Blastomycosis • D) Histoplasmosis Answer: B Rationale: Opportunistic systemic fungal infections occur in immunocompromised patients and include Aspergillosis, Candidiasis, Cryptococcosis, and Mucormycosis. Non- opportunistic infections, such as sporotrichosis, blastomycosis, and histoplasmosis, affect healthy individuals. Question 2 What is the drug of choice (DOC) for most systemic fungal infections? • A) Fluconazole • B) Amphotericin B • C) Itraconazole • D) Ketoconazole Answer: B Rationale: Amphotericin B is the DOC for most systemic fungal infections due to its broad-spectrum antifungal activity, despite its high toxicity. Question 3 Which antifungal is effective against both systemic and superficial fungal infections but has a black box warning for patients with heart failure? • A) Amphotericin B • B) Itraconazole • C) Fluconazole • D) Terbinafine Answer: B Rationale: Itraconazole is effective for both systemic and superficial fungal infections but has a BBW due to its negative inotropic effects, contraindicating its use in patients with heart failure. Question 4 Which antifungal is primarily used to treat superficial fungal infections, such as candidiasis?