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NURS 251 Pharmacology Final Exam
2025 – 100 Questions with Verified
Answers | 100% Correct | A+ Grade
Section 1: Pharmaceutics and Administration Routes (20
Questions)
Question 1 (Multiple-Choice)
Which administration route provides the fastest onset of action?
A) Oral
B) Sublingual
C) Transdermal
D) Intramuscular
Rationale: Sublingual administration bypasses the GI tract, allowing rapid absorption into the
bloodstream, per 2025 pharmacology guidelines.
Question 2 (Multiple-Choice)
What is the primary advantage of enteric-coated tablets?
A) Increase absorption speed
B) Prevent dissolution in the stomach
C) Enhance bioavailability
D) Reduce drug half-life
Rationale: Enteric-coated tablets resist stomach acid, dissolving in the intestines to protect the
drug or stomach lining, per NURS 251 curriculum.
Question 3 (Multiple-Choice)
A nurse administers a topical medication for a skin condition. What is the primary purpose?
A) Systemic effects
B) Local effects
C) Rapid absorption
D) Long-term release
, 2
Rationale: Topical medications target local skin or mucosal effects, per 2025 pharmacology
principles.
Question 4 (Multiple-Choice)
Which dosage form is designed for extended release?
A) Sustained-release tablet
B) Sublingual tablet
C) Suppository
D) Liquid solution
Rationale: Sustained-release tablets release the drug slowly over time, per NURS 251
pharmaceutics.
Question 5 (NGN: Fill-in-the-Blank)
What is the onset time for oral medications? (Fill in the blank.)
Answer: 30–60 minutes
Rationale: Oral medications require GI absorption, delaying onset to 30–60 minutes, per 2025
guidelines.
Question 6 (Multiple-Choice)
A nurse administers a subcutaneous injection. Which drug is suitable for this route?
A) Insulin
B) Nitroglycerin
C) Ibuprofen
D) Albuterol
Rationale: Insulin is inactivated in the GI tract, making subcutaneous injection appropriate, per
NURS 251 curriculum.
Question 7 (Multiple-Choice)
What is the primary purpose of a transdermal patch?
A) Immediate effect
B) Continuous drug release
C) Local skin treatment
D) Bypassing liver metabolism
Rationale: Transdermal patches provide steady drug absorption over hours, per 2025
pharmacology guidelines.
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Question 8 (Multiple-Choice)
Which route is used for nitroglycerin in acute chest pain?
A) Oral
B) Sublingual
C) Topical
D) Intravenous
Rationale: Sublingual nitroglycerin ensures rapid absorption for acute angina, per NURS 251
guidelines.
Question 9 (Multiple-Choice)
What is a key consideration for rectal administration?
A) Patient inability to take oral drugs
B) Rapid systemic absorption
C) Avoidance of first-pass metabolism
D) High bioavailability
Rationale: Rectal administration is used when oral intake is not possible, per 2025
pharmacology principles.
Question 10 (NGN: Multiple-Select)
Which routes bypass the gastrointestinal tract? (Select all that apply.)
A) Sublingual
B) Oral
C) Intravenous
D) Transdermal
E) Rectal
Answer: A, C, D
Rationale: Sublingual, intravenous, and transdermal routes avoid GI absorption, per NURS 251
curriculum.
Question 11 (Multiple-Choice)
A nurse administers an intramuscular injection. What is a key advantage?
A) Suitable for poorly absorbed oral drugs
B) Immediate onset
C) Avoids first-pass metabolism
D) Local effects
NURS 251 Pharmacology Final Exam
2025 – 100 Questions with Verified
Answers | 100% Correct | A+ Grade
Section 1: Pharmaceutics and Administration Routes (20
Questions)
Question 1 (Multiple-Choice)
Which administration route provides the fastest onset of action?
A) Oral
B) Sublingual
C) Transdermal
D) Intramuscular
Rationale: Sublingual administration bypasses the GI tract, allowing rapid absorption into the
bloodstream, per 2025 pharmacology guidelines.
Question 2 (Multiple-Choice)
What is the primary advantage of enteric-coated tablets?
A) Increase absorption speed
B) Prevent dissolution in the stomach
C) Enhance bioavailability
D) Reduce drug half-life
Rationale: Enteric-coated tablets resist stomach acid, dissolving in the intestines to protect the
drug or stomach lining, per NURS 251 curriculum.
Question 3 (Multiple-Choice)
A nurse administers a topical medication for a skin condition. What is the primary purpose?
A) Systemic effects
B) Local effects
C) Rapid absorption
D) Long-term release
, 2
Rationale: Topical medications target local skin or mucosal effects, per 2025 pharmacology
principles.
Question 4 (Multiple-Choice)
Which dosage form is designed for extended release?
A) Sustained-release tablet
B) Sublingual tablet
C) Suppository
D) Liquid solution
Rationale: Sustained-release tablets release the drug slowly over time, per NURS 251
pharmaceutics.
Question 5 (NGN: Fill-in-the-Blank)
What is the onset time for oral medications? (Fill in the blank.)
Answer: 30–60 minutes
Rationale: Oral medications require GI absorption, delaying onset to 30–60 minutes, per 2025
guidelines.
Question 6 (Multiple-Choice)
A nurse administers a subcutaneous injection. Which drug is suitable for this route?
A) Insulin
B) Nitroglycerin
C) Ibuprofen
D) Albuterol
Rationale: Insulin is inactivated in the GI tract, making subcutaneous injection appropriate, per
NURS 251 curriculum.
Question 7 (Multiple-Choice)
What is the primary purpose of a transdermal patch?
A) Immediate effect
B) Continuous drug release
C) Local skin treatment
D) Bypassing liver metabolism
Rationale: Transdermal patches provide steady drug absorption over hours, per 2025
pharmacology guidelines.
, 3
Question 8 (Multiple-Choice)
Which route is used for nitroglycerin in acute chest pain?
A) Oral
B) Sublingual
C) Topical
D) Intravenous
Rationale: Sublingual nitroglycerin ensures rapid absorption for acute angina, per NURS 251
guidelines.
Question 9 (Multiple-Choice)
What is a key consideration for rectal administration?
A) Patient inability to take oral drugs
B) Rapid systemic absorption
C) Avoidance of first-pass metabolism
D) High bioavailability
Rationale: Rectal administration is used when oral intake is not possible, per 2025
pharmacology principles.
Question 10 (NGN: Multiple-Select)
Which routes bypass the gastrointestinal tract? (Select all that apply.)
A) Sublingual
B) Oral
C) Intravenous
D) Transdermal
E) Rectal
Answer: A, C, D
Rationale: Sublingual, intravenous, and transdermal routes avoid GI absorption, per NURS 251
curriculum.
Question 11 (Multiple-Choice)
A nurse administers an intramuscular injection. What is a key advantage?
A) Suitable for poorly absorbed oral drugs
B) Immediate onset
C) Avoids first-pass metabolism
D) Local effects
