Pharmaceutics Exam Questions Correct
Solutions
What is bioavailability? - Answer ✔✔- the percentage of a drug dose that
actually reaches the systemic circulation chemically unchanged.
A drug administered by what routes has a high bioavailabilty - Answer ✔✔-
a drug that goes directly into the systemic circulation (IV, IM, IP, TP)
what is an example of a drug with a high bioavailaiblity - Answer ✔✔-
lithium
what is an example of a drug with a low bioavailaiblity - Answer ✔✔-
morphine
Drugs may have a low bioavailability due to what reasons? - Answer ✔✔- -
The drug does not dissolve readily (they pass through the gastrointestinal
system with little or no dissolution)
- Enzymes in the intestines may metabolize some of the drug before it is
absorbed
- The liver metabolizes some of the drug on its first pass through the liver
on the way to the systemic circulation
Oral drugs may come in immediate release formulations such as - Answer
✔✔- liquids for varying rates of absorption and bioavailability.
The varying rates of bioavailability and absorption are dependent on what?
- Answer ✔✔- The type of formulation and the degree of first pass
metabolism.
What is important to know about oral drug solutions - Answer ✔✔- more
readily absorbed and have a high availability
What type of drug has the lowest bioavailaibilty - Answer ✔✔- time release
capsules
Solutions
What is bioavailability? - Answer ✔✔- the percentage of a drug dose that
actually reaches the systemic circulation chemically unchanged.
A drug administered by what routes has a high bioavailabilty - Answer ✔✔-
a drug that goes directly into the systemic circulation (IV, IM, IP, TP)
what is an example of a drug with a high bioavailaiblity - Answer ✔✔-
lithium
what is an example of a drug with a low bioavailaiblity - Answer ✔✔-
morphine
Drugs may have a low bioavailability due to what reasons? - Answer ✔✔- -
The drug does not dissolve readily (they pass through the gastrointestinal
system with little or no dissolution)
- Enzymes in the intestines may metabolize some of the drug before it is
absorbed
- The liver metabolizes some of the drug on its first pass through the liver
on the way to the systemic circulation
Oral drugs may come in immediate release formulations such as - Answer
✔✔- liquids for varying rates of absorption and bioavailability.
The varying rates of bioavailability and absorption are dependent on what?
- Answer ✔✔- The type of formulation and the degree of first pass
metabolism.
What is important to know about oral drug solutions - Answer ✔✔- more
readily absorbed and have a high availability
What type of drug has the lowest bioavailaibilty - Answer ✔✔- time release
capsules
