6/29/25, 10:02 AM CTBS Study Guide (2025 updated) QUESTIONS AND ANSWERS (DETAILED & ELABORATED) fully solved
CTBS Study Guide (2025 updated)
QUESTIONS AND ANSWERS
(DETAILED & ELABORATED) fully
solved
Blood component Any part of a single-donor unit of blood separated by physical or
mechanical means.
Cardiac Tissue (C) Valved conduits, non-valved conduits, aortoilliac grafts, and
patch grafts.
viable cells that are autologous or allogenic, committed
Cellular Tissue (CT)
or uncommitted, and non- expanded.
Relating to a death certificated, an original,
Certified Copy
authenticated form produced by a governing authority.
any written or oral communication alleging the quality,
claim
durability, reliability, infectious disease risk, or
performance of tissue.
A person who consents to collection and/or storage of
reproductive tissues for artificial insemination or
Client depositor (R)
assisted reproductive technology procedures for
themselves(yes) or a sexually intimate partner, not
considered a reproductive tissue donor.
The time interval from subjecting cardiac
Cold Ischemic time (C)
tissue to cold rinse (or transport) solution
at recovery to the beginning of
disinfection.
The time interval from subjecting vascular tissue to transport
Cold Ischemic time (V)
solution and wet ice temperatures at recovery to the beginning
of disinfection.
The acquisition of reproductive tissue from a donor or
Collection (R)
client depositor by surgical or non-surgical procedures.
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,6/29/25, 10:02 AM CTBS Study Guide (2025 updated) QUESTIONS AND ANSWERS (DETAILED & ELABORATED) fully solved
A protein or polysaccharide solution that can be used
Colloid to increase or maintain osmotic (oncotic) pressure in
the intravascular compartment such as albumin,
dextran, hetastarch, or certain blood components, such
as plasma and platelets.
Any written or oral communication concerning
Complaint dissatisfaction with the identity, quality, packaging,
durability, reliability, safety, effectiveness or
performance of tissue.
The ability of an employee to acceptably perform tasks
Competency
for which he/she has been trained.
The evaluation of the ability of an
competency assessment
employee to acceptably perform tasks for
which he/she has been trained.
Any tissue bank, tissue distribution intermediary, tissue
Consignee
dispensing service, or end- user that receives
Container An enclosure for one finished unit of transplantable tissue.
Those functions pertaining to the recovery, screening, testing,
Contract services processing,
storage, and/or distribution of human tissue that another
establishment agrees to perform
Restricted work areas of low microbial and
controlled areas
particulate content in which non- sterile
materials are prepared.
Correction related to conformity, remedial action to eliminate a detected
nonconformity
Action to eliminate the cause and prevent recurrence
Corrective action
of a detected nonconformity or other undesirable
situation
classification of a supply, reagent, material, instrument
Critical
or equipment that can affect the quality and/or safety
of tissue.
Restricted work areas where cells, tissue, containers
Critical areas
and/or closures are exposed to the environment.
the transfer of infectious agents from one tissue to
Cross-contamination
another from either the same donor or a different
donor.
… 2/16
, 6/29/25, 10:02 AM CTBS Study Guide (2025 updated) QUESTIONS AND ANSWERS (DETAILED & ELABORATED) fully solved
Frozen with the addition of, or in a solution containing
Cryopreserved
a cryoprotectant agent such as glycerol or
dimethylfulfoxide
An additive that serves to minimize osmotic imbalances that occur
with the
Cryoprotectant progression of freezing fronts through a substance, and
is intended to limit the amount of cell damage
caused by cell shrinkage and intracellular ice formation.
A balanced salt and/or glucose solution used for electrolyte
Crystalloid replacement or to
increase intravascular volume, such as saline solution,
Ringers lactate solution or 5% dextrose water or total
parental nutrition.
Cleaning the environment, facilities, and or surfaces (sanitation) or
Decontamination
instruments,
supplies, and equipment, with the intent to remove or reduce
pathogenic microbes.
Dehydration The removal or water from tissue.
The time interval between subjecting tissue to
Disinfection time (C,V)
disinfection solution and transferring tissue to rinsing
solutions in preparation for preservation.
Desiccation The removal of water from tissue.
Deviation An event that is a departure from a procedure or normal
practice.
A reproductive cell or tissue donor who is
Directed donor (R)
known to the recipient but is not her sexually
intimate partner.
An agent capable of reducing the number of viable
Disinfectant
microorganisms. Might not kill spores
A process that reduces the number of microorganisms
Disinfection
on tissue, but may not destroy all microbial forms, such
as spores and viruses.
A facility responsible for the receipt, maintenance and delivery to
the
Dispensing service ultimate user (e.g., transplanting surgeon, surgical center
or research facility) of tissue for
transplantation or research.
Disposition The final destination of tissue
… 3/16
CTBS Study Guide (2025 updated)
QUESTIONS AND ANSWERS
(DETAILED & ELABORATED) fully
solved
Blood component Any part of a single-donor unit of blood separated by physical or
mechanical means.
Cardiac Tissue (C) Valved conduits, non-valved conduits, aortoilliac grafts, and
patch grafts.
viable cells that are autologous or allogenic, committed
Cellular Tissue (CT)
or uncommitted, and non- expanded.
Relating to a death certificated, an original,
Certified Copy
authenticated form produced by a governing authority.
any written or oral communication alleging the quality,
claim
durability, reliability, infectious disease risk, or
performance of tissue.
A person who consents to collection and/or storage of
reproductive tissues for artificial insemination or
Client depositor (R)
assisted reproductive technology procedures for
themselves(yes) or a sexually intimate partner, not
considered a reproductive tissue donor.
The time interval from subjecting cardiac
Cold Ischemic time (C)
tissue to cold rinse (or transport) solution
at recovery to the beginning of
disinfection.
The time interval from subjecting vascular tissue to transport
Cold Ischemic time (V)
solution and wet ice temperatures at recovery to the beginning
of disinfection.
The acquisition of reproductive tissue from a donor or
Collection (R)
client depositor by surgical or non-surgical procedures.
… 1/16
,6/29/25, 10:02 AM CTBS Study Guide (2025 updated) QUESTIONS AND ANSWERS (DETAILED & ELABORATED) fully solved
A protein or polysaccharide solution that can be used
Colloid to increase or maintain osmotic (oncotic) pressure in
the intravascular compartment such as albumin,
dextran, hetastarch, or certain blood components, such
as plasma and platelets.
Any written or oral communication concerning
Complaint dissatisfaction with the identity, quality, packaging,
durability, reliability, safety, effectiveness or
performance of tissue.
The ability of an employee to acceptably perform tasks
Competency
for which he/she has been trained.
The evaluation of the ability of an
competency assessment
employee to acceptably perform tasks for
which he/she has been trained.
Any tissue bank, tissue distribution intermediary, tissue
Consignee
dispensing service, or end- user that receives
Container An enclosure for one finished unit of transplantable tissue.
Those functions pertaining to the recovery, screening, testing,
Contract services processing,
storage, and/or distribution of human tissue that another
establishment agrees to perform
Restricted work areas of low microbial and
controlled areas
particulate content in which non- sterile
materials are prepared.
Correction related to conformity, remedial action to eliminate a detected
nonconformity
Action to eliminate the cause and prevent recurrence
Corrective action
of a detected nonconformity or other undesirable
situation
classification of a supply, reagent, material, instrument
Critical
or equipment that can affect the quality and/or safety
of tissue.
Restricted work areas where cells, tissue, containers
Critical areas
and/or closures are exposed to the environment.
the transfer of infectious agents from one tissue to
Cross-contamination
another from either the same donor or a different
donor.
… 2/16
, 6/29/25, 10:02 AM CTBS Study Guide (2025 updated) QUESTIONS AND ANSWERS (DETAILED & ELABORATED) fully solved
Frozen with the addition of, or in a solution containing
Cryopreserved
a cryoprotectant agent such as glycerol or
dimethylfulfoxide
An additive that serves to minimize osmotic imbalances that occur
with the
Cryoprotectant progression of freezing fronts through a substance, and
is intended to limit the amount of cell damage
caused by cell shrinkage and intracellular ice formation.
A balanced salt and/or glucose solution used for electrolyte
Crystalloid replacement or to
increase intravascular volume, such as saline solution,
Ringers lactate solution or 5% dextrose water or total
parental nutrition.
Cleaning the environment, facilities, and or surfaces (sanitation) or
Decontamination
instruments,
supplies, and equipment, with the intent to remove or reduce
pathogenic microbes.
Dehydration The removal or water from tissue.
The time interval between subjecting tissue to
Disinfection time (C,V)
disinfection solution and transferring tissue to rinsing
solutions in preparation for preservation.
Desiccation The removal of water from tissue.
Deviation An event that is a departure from a procedure or normal
practice.
A reproductive cell or tissue donor who is
Directed donor (R)
known to the recipient but is not her sexually
intimate partner.
An agent capable of reducing the number of viable
Disinfectant
microorganisms. Might not kill spores
A process that reduces the number of microorganisms
Disinfection
on tissue, but may not destroy all microbial forms, such
as spores and viruses.
A facility responsible for the receipt, maintenance and delivery to
the
Dispensing service ultimate user (e.g., transplanting surgeon, surgical center
or research facility) of tissue for
transplantation or research.
Disposition The final destination of tissue
… 3/16
