STUDENT COMPANION FUNDAMENTALS OF
Biochemistry
LIFE AT
THE MOLECULAR
LEVEL
Voet Voet Pratt
FOURTH EDITION
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
Donald Voet Judith G. Voet Charlotte W. Pratt
,ThisZpageZisZintentionallyZleftZblank
,STUDENT COMPANION TO ACCOMPANY Z Z Z Z
FUNDAMENTALS OF Z
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Z Z Z Z
Fourth Edition Z
Akif Uzman
Z
University of Houston Z Z
Jerry Johnson
Z
University of Houston Z Z
Joseph Eichberg Z
University of Houston Z Z
William Widger Z
University of Houston Z Z
Donald Voet Z
University of Pennsylvania Z Z
Judith G. Voet Z Z
Swarthmore College Z
Charlotte W. Pratt Z Z
Seattle, Washington Z
JOHNZWILEYZ&ZSONS,ZINC
, CoverZDesignerZMadelynZLesure
CoverZIllustrationZNormZChristiansen
CoverZPhotos
(VitruvianZMan):Z©ZOdysseus/AlamyZandZ©ZDennisZHallinan/Alamy
MolecularZstructuresZclockwiseZfromZtop:ZbasedZonZX-
rayZstructuresZthatZwereZrespectivelyZdeterminedZbyZRichardZDickersonZandZHoraceZDrew,ZCaltech;ZGer
ardZBunick,ZUniversityZofZTennessee;ZThomasZSteitz,ZYaleZUniversity;ZAlfonsoZMondragón,ZNorthwest
ernZUniversity;ZVenkiZRamakrishnan,ZMRCZLaboratoryZofZMolecularZBiology,ZCambridge,ZU.K.;ZAndr
ewZLeslieZandZJohnZWalker,ZMRCZLaboratoryZofZMolecularZBiology,ZCambridge,ZU.K.
FoundedZinZ1807,ZJohnZWileyZ&ZSons,ZInc.ZhasZbeenZaZvaluedZsourceZofZknowledgeZandZunderstandingZfor
ZmoreZthanZ200Zyears,ZhelpingZpeopleZaroundZtheZworldZmeetZtheirZneedsZandZfulfillZtheirZaspirations.ZOurZ
companyZisZbuiltZonZaZfoundationZofZprinciplesZthatZincludeZresponsibilityZtoZtheZcommunitiesZweZserveZan
dZwhereZweZliveZandZwork.ZInZ2008,ZweZlaunchedZaZCorporateZCitizenshipZInitiative,ZaZglobalZeffortZtoZadd
ressZtheZenvironmental,Zsocial,Zeconomic,ZandZethicalZchallengesZweZfaceZinZourZbusiness.ZAmongZtheZissu
esZweZareZaddressingZareZcarbonZimpact,ZpaperZspecificationsZandZprocurement,ZethicalZconductZwithinZour
ZbusinessZandZamongZourZvendors,ZandZcommunityZandZcharitableZsupport.ZForZmoreZinformation,ZpleaseZv
isitZourZwebsite:Zwww.wiley.com/go/citizenship.
CopyrightZ©Z2012 JohnZWileyZ&ZSons,ZInc.
AllZrightsZreserved.ZNoZpartZofZthisZpublicationZmayZbeZreproduced,ZstoredZinZaZretrievalZsystemZorZtrans
mittedZinZanyZformZorZbyZanyZmeans,Zelectronic,Zmechanical,Zphotocopying,Zrecording,ZscanningZorZother
wise,ZexceptZasZpermittedZunderZSectionsZ107ZorZ108ZofZtheZ1976ZUnitedZStatesZCopyrightZAct,ZwithoutZe
itherZtheZpriorZwrittenZpermissionZofZtheZPublisher,ZorZauthorizationZthroughZpaymentZofZtheZappropriateZ
per-
copyZfeeZtoZtheZCopyrightZClearanceZCenter,ZInc.,Z222ZRosewoodZDrive,ZDanvers,ZMAZ01923,ZwebsiteZ
www.copyright.com.ZRequestsZtoZtheZPublisherZforZpermissionZshouldZbeZaddressedZtoZtheZPermissionsZ
Department,ZJohnZWileyZ&ZSons,ZInc.Z111ZRiverZStreet,ZHoboken,ZNJZ07030-5774,Z(201)
748-6011,ZfaxZ(201)Z748-6008,ZwebsiteZhttp://www.wiley.com/go/permissions.
ToZorderZbooksZorZforZcustomerZservice,ZpleaseZcallZ1-800-CALLZWILEYZ(225-5945).
StudentZCompanionZ(paperback) ISBN-13ZZ978-1-1182-1827-3
PrintedZinZtheZUnitedZStatesZofZAmerica
10987654321
Biochemistry
LIFE AT
THE MOLECULAR
LEVEL
Voet Voet Pratt
FOURTH EDITION
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
Donald Voet Judith G. Voet Charlotte W. Pratt
,ThisZpageZisZintentionallyZleftZblank
,STUDENT COMPANION TO ACCOMPANY Z Z Z Z
FUNDAMENTALS OF Z
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Z Z Z Z
Fourth Edition Z
Akif Uzman
Z
University of Houston Z Z
Jerry Johnson
Z
University of Houston Z Z
Joseph Eichberg Z
University of Houston Z Z
William Widger Z
University of Houston Z Z
Donald Voet Z
University of Pennsylvania Z Z
Judith G. Voet Z Z
Swarthmore College Z
Charlotte W. Pratt Z Z
Seattle, Washington Z
JOHNZWILEYZ&ZSONS,ZINC
, CoverZDesignerZMadelynZLesure
CoverZIllustrationZNormZChristiansen
CoverZPhotos
(VitruvianZMan):Z©ZOdysseus/AlamyZandZ©ZDennisZHallinan/Alamy
MolecularZstructuresZclockwiseZfromZtop:ZbasedZonZX-
rayZstructuresZthatZwereZrespectivelyZdeterminedZbyZRichardZDickersonZandZHoraceZDrew,ZCaltech;ZGer
ardZBunick,ZUniversityZofZTennessee;ZThomasZSteitz,ZYaleZUniversity;ZAlfonsoZMondragón,ZNorthwest
ernZUniversity;ZVenkiZRamakrishnan,ZMRCZLaboratoryZofZMolecularZBiology,ZCambridge,ZU.K.;ZAndr
ewZLeslieZandZJohnZWalker,ZMRCZLaboratoryZofZMolecularZBiology,ZCambridge,ZU.K.
FoundedZinZ1807,ZJohnZWileyZ&ZSons,ZInc.ZhasZbeenZaZvaluedZsourceZofZknowledgeZandZunderstandingZfor
ZmoreZthanZ200Zyears,ZhelpingZpeopleZaroundZtheZworldZmeetZtheirZneedsZandZfulfillZtheirZaspirations.ZOurZ
companyZisZbuiltZonZaZfoundationZofZprinciplesZthatZincludeZresponsibilityZtoZtheZcommunitiesZweZserveZan
dZwhereZweZliveZandZwork.ZInZ2008,ZweZlaunchedZaZCorporateZCitizenshipZInitiative,ZaZglobalZeffortZtoZadd
ressZtheZenvironmental,Zsocial,Zeconomic,ZandZethicalZchallengesZweZfaceZinZourZbusiness.ZAmongZtheZissu
esZweZareZaddressingZareZcarbonZimpact,ZpaperZspecificationsZandZprocurement,ZethicalZconductZwithinZour
ZbusinessZandZamongZourZvendors,ZandZcommunityZandZcharitableZsupport.ZForZmoreZinformation,ZpleaseZv
isitZourZwebsite:Zwww.wiley.com/go/citizenship.
CopyrightZ©Z2012 JohnZWileyZ&ZSons,ZInc.
AllZrightsZreserved.ZNoZpartZofZthisZpublicationZmayZbeZreproduced,ZstoredZinZaZretrievalZsystemZorZtrans
mittedZinZanyZformZorZbyZanyZmeans,Zelectronic,Zmechanical,Zphotocopying,Zrecording,ZscanningZorZother
wise,ZexceptZasZpermittedZunderZSectionsZ107ZorZ108ZofZtheZ1976ZUnitedZStatesZCopyrightZAct,ZwithoutZe
itherZtheZpriorZwrittenZpermissionZofZtheZPublisher,ZorZauthorizationZthroughZpaymentZofZtheZappropriateZ
per-
copyZfeeZtoZtheZCopyrightZClearanceZCenter,ZInc.,Z222ZRosewoodZDrive,ZDanvers,ZMAZ01923,ZwebsiteZ
www.copyright.com.ZRequestsZtoZtheZPublisherZforZpermissionZshouldZbeZaddressedZtoZtheZPermissionsZ
Department,ZJohnZWileyZ&ZSons,ZInc.Z111ZRiverZStreet,ZHoboken,ZNJZ07030-5774,Z(201)
748-6011,ZfaxZ(201)Z748-6008,ZwebsiteZhttp://www.wiley.com/go/permissions.
ToZorderZbooksZorZforZcustomerZservice,ZpleaseZcallZ1-800-CALLZWILEYZ(225-5945).
StudentZCompanionZ(paperback) ISBN-13ZZ978-1-1182-1827-3
PrintedZinZtheZUnitedZStatesZofZAmerica
10987654321
