HESI PHARMACOLOGY EXIT EXAM BANK
V1-V5 EXAM 2025/2026 \ NCLEX NGN STYLE
QUESTIONS WITH 100% WELL
RESEARCHED CORRECT ANSWERS AND
STUDY GUIDE |EXPERT VERIFIED
|LATEST UPDATE /A+ GRADE ASSURED
A client with diabetes mellitus visits a health care clinic.
The client's diabetes mellitus previously had been well
controlled with glyburide (DiaBeta) daily, but recently the
fasting blood glucose level has been 180 to 200 mg/dL.
Which medication, if added to the client's regimen, may
have contributed to the hyperglycemia?
1. Prednisone
2. Phenelzine (Nardil)
3. Atenolol (Tenormin)
4. Allopurinol (Zyloprim) - ....ANSWER...1. Prednisone
Rationale:
Prednisone may decrease the effect of oral hypoglycemics,
insulin, diuretics, and potassium supplements. Option 2, a
monoamine oxidase inhibitor, and option 3, a β- blocker,
have their own intrinsic hypoglycemic activity. Option 4
decreases urinary excretion of sulfonylurea agents, causing
1
,increased levels of the oral agents, which can lead to
hypoglycemia.
A community health nurse visits a client at home.
Prednisone 10 mg orally daily has been prescribed for the
client and the nurse reinforces teaching for the client about
the medication. Which statement, if made by the client,
indicates that further teaching is necessary?
1. "I can take aspirin or my antihistamine if I need it."
2. "I need to take the medication every day at the same
time."
3. "I need to avoid coffee, tea, cola, and chocolate in my
diet."
2
,4. "If I gain more than 5 pounds a week, I will call my
doctor." - ....ANSWER...1. "I can take aspirin or my
antihistamine if I need it."
Rationale:
Aspirin and other over-the-counter medications should not
be taken unless the client consults with the health care
provider (HCP). The client needs to take the medication at
the same time every day and should be instructed not to
stop the medication. A slight weight gain as a result of an
improved appetite is expected, but after the dosage is
stabilized, a weight gain of 5 lb or more weekly should be
reported to the HCP. Caffeine- containing foods and fluids
need to be avoided because they may contribute to steroid-
ulcer development.
Desmopressin acetate (DDAVP) is prescribed for the
treatment of diabetes insipidus. The nurse monitors the
client after medication administration for which
therapeutic response?
1. Decreased urinary output
2. Decreased blood pressure
3. Decreased peripheral edema
3
, 4. Decreased blood glucose level - ....ANSWER...1.
Decreased urinary output
Rationale
:Desmopressin promotes renal conservation of water. The
hormone carries out this action by acting on the collecting
ducts of the kidney to increase their permeability to water,
which results in increased water reabsorption. The
therapeutic effect of this medication would be manifested
by a decreased urine output. Options 2, 3, and 4 are
unrelated to the effects of this medication.
he home health care nurse is visiting a client who was
recently diagnosed with type 2 diabetes mellitus. The
client is prescribed repaglinide (Prandin) and metformin
(Glucophage) and asks the nurse to explain these
medications. The nurse should reinforce which instructions
to the client? Select all that apply.
1. Diarrhea can occur secondary to the metformin.
2. The repaglinide is not taken if a meal is skipped.
3. The repaglinide is taken 30 minutes before eating.
4. Candy or another simple sugar is carried and used to
treat mild hypoglycemia episodes.
4
V1-V5 EXAM 2025/2026 \ NCLEX NGN STYLE
QUESTIONS WITH 100% WELL
RESEARCHED CORRECT ANSWERS AND
STUDY GUIDE |EXPERT VERIFIED
|LATEST UPDATE /A+ GRADE ASSURED
A client with diabetes mellitus visits a health care clinic.
The client's diabetes mellitus previously had been well
controlled with glyburide (DiaBeta) daily, but recently the
fasting blood glucose level has been 180 to 200 mg/dL.
Which medication, if added to the client's regimen, may
have contributed to the hyperglycemia?
1. Prednisone
2. Phenelzine (Nardil)
3. Atenolol (Tenormin)
4. Allopurinol (Zyloprim) - ....ANSWER...1. Prednisone
Rationale:
Prednisone may decrease the effect of oral hypoglycemics,
insulin, diuretics, and potassium supplements. Option 2, a
monoamine oxidase inhibitor, and option 3, a β- blocker,
have their own intrinsic hypoglycemic activity. Option 4
decreases urinary excretion of sulfonylurea agents, causing
1
,increased levels of the oral agents, which can lead to
hypoglycemia.
A community health nurse visits a client at home.
Prednisone 10 mg orally daily has been prescribed for the
client and the nurse reinforces teaching for the client about
the medication. Which statement, if made by the client,
indicates that further teaching is necessary?
1. "I can take aspirin or my antihistamine if I need it."
2. "I need to take the medication every day at the same
time."
3. "I need to avoid coffee, tea, cola, and chocolate in my
diet."
2
,4. "If I gain more than 5 pounds a week, I will call my
doctor." - ....ANSWER...1. "I can take aspirin or my
antihistamine if I need it."
Rationale:
Aspirin and other over-the-counter medications should not
be taken unless the client consults with the health care
provider (HCP). The client needs to take the medication at
the same time every day and should be instructed not to
stop the medication. A slight weight gain as a result of an
improved appetite is expected, but after the dosage is
stabilized, a weight gain of 5 lb or more weekly should be
reported to the HCP. Caffeine- containing foods and fluids
need to be avoided because they may contribute to steroid-
ulcer development.
Desmopressin acetate (DDAVP) is prescribed for the
treatment of diabetes insipidus. The nurse monitors the
client after medication administration for which
therapeutic response?
1. Decreased urinary output
2. Decreased blood pressure
3. Decreased peripheral edema
3
, 4. Decreased blood glucose level - ....ANSWER...1.
Decreased urinary output
Rationale
:Desmopressin promotes renal conservation of water. The
hormone carries out this action by acting on the collecting
ducts of the kidney to increase their permeability to water,
which results in increased water reabsorption. The
therapeutic effect of this medication would be manifested
by a decreased urine output. Options 2, 3, and 4 are
unrelated to the effects of this medication.
he home health care nurse is visiting a client who was
recently diagnosed with type 2 diabetes mellitus. The
client is prescribed repaglinide (Prandin) and metformin
(Glucophage) and asks the nurse to explain these
medications. The nurse should reinforce which instructions
to the client? Select all that apply.
1. Diarrhea can occur secondary to the metformin.
2. The repaglinide is not taken if a meal is skipped.
3. The repaglinide is taken 30 minutes before eating.
4. Candy or another simple sugar is carried and used to
treat mild hypoglycemia episodes.
4
