Test bank for Tietz Fundamentals of Clinical Chemistry and
p p p p p p p p
Molecular Diagnostics,
p p p
8th Edition by Nader Rifai, PhD
p p p p p p
Chapters 1 - 49
p p p p
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
p p p p p p p p
p
p p
Table of contents:
p p
I. Principles Of Laboratory Medicine
p p p p
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
p p p p p p p p
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
p p p p p p p p p p p
Chapter 3. Clinical Evaluation of Methods
p p p p p
Chapter 4. Evidence-Based Laboratory Medicine
p p p p
Chapter 5. Establishment and Use of Reference Values
p p p p p p p
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
p p p p p p p p
Chapter 7. Quality Management
p p p
II. Analytical Techniques And Instrumentation
p p p p
Chapter 8. Principles of Basic Techniques and Laboratory Safety
p p p p p p p p
Chapter 9. Optical Techniques
p p p
Chapter 10. Electrochemistry and Chemical Sensors
p p p p p
Chapter 11. Electrophoresis
p p
Chapter 12. Chromatography
p p
Chapter 13. Mass Spectrometry
p p p
Chapter 14. Enzyme and Rate Analyses
p p p p p
Chapter 15. Immunochemical Techniques
p p p
Chapter 16 Automationp p
Chapter 17. Point-of-Care Instrumentation
p p p
III. Analytesp
Chapter 18. Amino Acids, Peptides, and Proteins
p p p p p p
Chapter 19. Serum Enzymes
p p p
Chapter 20. Tumor Markers and Cancer Genes
p p p p p p
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
p p p p p p p p p p p
Chapter 22. Carbohydrates
p p
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
p p p p p p p p p
Chapter 24. Electrolytes and Blood Gases
p p p p p
Chapter 25. Hormones p p
Chapter 26. Catecholamines and Serotonin
p p p p
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
p p p p p p
Chapter 28. Hemoglobin, Iron, and Bilirubin
p p p p p
Chapter 29. Porphyrins and Porphyrias
p p p p
Chapter 30. Therapeutic Drugs and Their Management
p p p p p p
Chapter 31. Clinical Toxicology
p p p
Chapter 32. Toxic Metals
p p p
IV. Pathophysiology
p
Chapter 33. Diabetes p p
,Chapter 34. Cardiovascular Disease
p p p
Chapter 35. Kidney Disease
p p p
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
p p p p p p p p p p
Chapter 37. Liver Disease
p pp p
Chapter 38. Gastrointestinal and Pancreatic Diseases
p p p p p
Chapter 39. Disorders of Bone and Mineral Metabolism
p pp p p p p p
Chapter 40. Disorders of the Pituitary Gland
p pp p p p p
Chapter 41. Disorders of the Adrenal Cortex
p p p p p p
Chapter 42. Thyroid Disorders
p p p
Chapter 43. Reproduction-Related Disorders
p p p
Chapter 44. Pregnancy and Prenatal Testing
p pp p p p
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
p p p p p p p p
Chapter 46. Pharmacogenetics
p p
V. Molecular Diagnostics
p p
Chapter 47. Principles of Molecular Biology
p p p p p
Chapter 48. Nucleic Acid Techniques and Applications
p p p p p p
Chapter 49. Genomes and Nucleic Acid Alterations
p p p p p p
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
p p p p p p p p
TestBank
p p
MULTIPLE CHOICE p
1. An individual working in a clinical chemistry laboratory is married to a sales representative who
p p p p p p p p p p p p p p
works for a company that sells chemistry laboratory supplies. When the laboratory manager
p p p p p p p p p p p p p
requests a list of needed supplies, cost of supplies, and vendors, this individual onlyrecommends
p p p p p p p p p p p p p p p
the spouse’s company as the vendor. This is considered to be a(n):
p p p p p p p p p p p p
a. accounting issue. p
b. possible conflict of interest. p p p
c. maintenance of confidentiality issue. p p p
d. problem with resource allocation. p p p
ANS: B p
Concern has been raised over the interrelationships between practitioners in the medical fieldand
p p p p p p p p p p p p p
commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
p p p p p p p p p p p
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
p p p p p p p p p
and providers of diagnostic equipment and supplies. These concerns led the National Institutes of
p p p p p p p p p p p p p p
Health (NIH) in 1995 to require official institutional review of financial disclosure by researchers
p p p p p p p p p p p p p p
and management of situations in which disclosure indicates potentialconflicts of interest.
p p p p p p p p p p p p
DIF: 1 REF: Page 4-5 pp p p OBJ: 6 |7 p p p
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the
p p p p p p p p p p p p p p p
pain following her recent surgery. A friend of the patient claims that the same
p p p p p p p p p p p p p p
painkiller“worked wonders” to reduce her pain after the same surgery. The physician states
p p p p p p p p p p p p p p
that the difference in the effect of the drug might be caused by
p p p , which is studied in p p p p p p p p p p p p p p
pharmacogenetics.
p
a. epidemiology
b. an inherited disease p p
c. a conflict of interest p p p
d. a genetic variation in drug-metabolizing enzymes
p p p p p
ANS: D p
Pharmacogenetics is the study of the genetic variation of drug metabolism p p p p p p p p p p
betweenindividuals.
p p
DIF: 1 REF: Page 3 pp p p OBJ: 1 p
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the name
p p p p p p p p p p p p p p p
of a close friend printed on the bar-coded label. The genetic test that is ordered on thefriend’s
p p p p p p p p p p p p p p p p p p
sample would provide diagnostic information about a disorder that has a poor prognosis, and
p p p p p p p p p p p p p p
the test is usually performed by John. He asks a fellow employee to analyzethe sample for him
p p p p p p p p p p p p p p p p p p
and not divulge the results. This ethical issue concerns:
p p p p p p p p p
a. confidentiality of patient genetic and medical information. p p p p p p
b. a conflict of interest. p p p
c. resource allocation. p
d. diagnostic accuracy. p
p p p p p p p p
Molecular Diagnostics,
p p p
8th Edition by Nader Rifai, PhD
p p p p p p
Chapters 1 - 49
p p p p
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
p p p p p p p p
p
p p
Table of contents:
p p
I. Principles Of Laboratory Medicine
p p p p
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
p p p p p p p p
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
p p p p p p p p p p p
Chapter 3. Clinical Evaluation of Methods
p p p p p
Chapter 4. Evidence-Based Laboratory Medicine
p p p p
Chapter 5. Establishment and Use of Reference Values
p p p p p p p
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
p p p p p p p p
Chapter 7. Quality Management
p p p
II. Analytical Techniques And Instrumentation
p p p p
Chapter 8. Principles of Basic Techniques and Laboratory Safety
p p p p p p p p
Chapter 9. Optical Techniques
p p p
Chapter 10. Electrochemistry and Chemical Sensors
p p p p p
Chapter 11. Electrophoresis
p p
Chapter 12. Chromatography
p p
Chapter 13. Mass Spectrometry
p p p
Chapter 14. Enzyme and Rate Analyses
p p p p p
Chapter 15. Immunochemical Techniques
p p p
Chapter 16 Automationp p
Chapter 17. Point-of-Care Instrumentation
p p p
III. Analytesp
Chapter 18. Amino Acids, Peptides, and Proteins
p p p p p p
Chapter 19. Serum Enzymes
p p p
Chapter 20. Tumor Markers and Cancer Genes
p p p p p p
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
p p p p p p p p p p p
Chapter 22. Carbohydrates
p p
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
p p p p p p p p p
Chapter 24. Electrolytes and Blood Gases
p p p p p
Chapter 25. Hormones p p
Chapter 26. Catecholamines and Serotonin
p p p p
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
p p p p p p
Chapter 28. Hemoglobin, Iron, and Bilirubin
p p p p p
Chapter 29. Porphyrins and Porphyrias
p p p p
Chapter 30. Therapeutic Drugs and Their Management
p p p p p p
Chapter 31. Clinical Toxicology
p p p
Chapter 32. Toxic Metals
p p p
IV. Pathophysiology
p
Chapter 33. Diabetes p p
,Chapter 34. Cardiovascular Disease
p p p
Chapter 35. Kidney Disease
p p p
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
p p p p p p p p p p
Chapter 37. Liver Disease
p pp p
Chapter 38. Gastrointestinal and Pancreatic Diseases
p p p p p
Chapter 39. Disorders of Bone and Mineral Metabolism
p pp p p p p p
Chapter 40. Disorders of the Pituitary Gland
p pp p p p p
Chapter 41. Disorders of the Adrenal Cortex
p p p p p p
Chapter 42. Thyroid Disorders
p p p
Chapter 43. Reproduction-Related Disorders
p p p
Chapter 44. Pregnancy and Prenatal Testing
p pp p p p
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
p p p p p p p p
Chapter 46. Pharmacogenetics
p p
V. Molecular Diagnostics
p p
Chapter 47. Principles of Molecular Biology
p p p p p
Chapter 48. Nucleic Acid Techniques and Applications
p p p p p p
Chapter 49. Genomes and Nucleic Acid Alterations
p p p p p p
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
p p p p p p p p
TestBank
p p
MULTIPLE CHOICE p
1. An individual working in a clinical chemistry laboratory is married to a sales representative who
p p p p p p p p p p p p p p
works for a company that sells chemistry laboratory supplies. When the laboratory manager
p p p p p p p p p p p p p
requests a list of needed supplies, cost of supplies, and vendors, this individual onlyrecommends
p p p p p p p p p p p p p p p
the spouse’s company as the vendor. This is considered to be a(n):
p p p p p p p p p p p p
a. accounting issue. p
b. possible conflict of interest. p p p
c. maintenance of confidentiality issue. p p p
d. problem with resource allocation. p p p
ANS: B p
Concern has been raised over the interrelationships between practitioners in the medical fieldand
p p p p p p p p p p p p p
commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
p p p p p p p p p p p
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
p p p p p p p p p
and providers of diagnostic equipment and supplies. These concerns led the National Institutes of
p p p p p p p p p p p p p p
Health (NIH) in 1995 to require official institutional review of financial disclosure by researchers
p p p p p p p p p p p p p p
and management of situations in which disclosure indicates potentialconflicts of interest.
p p p p p p p p p p p p
DIF: 1 REF: Page 4-5 pp p p OBJ: 6 |7 p p p
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the
p p p p p p p p p p p p p p p
pain following her recent surgery. A friend of the patient claims that the same
p p p p p p p p p p p p p p
painkiller“worked wonders” to reduce her pain after the same surgery. The physician states
p p p p p p p p p p p p p p
that the difference in the effect of the drug might be caused by
p p p , which is studied in p p p p p p p p p p p p p p
pharmacogenetics.
p
a. epidemiology
b. an inherited disease p p
c. a conflict of interest p p p
d. a genetic variation in drug-metabolizing enzymes
p p p p p
ANS: D p
Pharmacogenetics is the study of the genetic variation of drug metabolism p p p p p p p p p p
betweenindividuals.
p p
DIF: 1 REF: Page 3 pp p p OBJ: 1 p
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the name
p p p p p p p p p p p p p p p
of a close friend printed on the bar-coded label. The genetic test that is ordered on thefriend’s
p p p p p p p p p p p p p p p p p p
sample would provide diagnostic information about a disorder that has a poor prognosis, and
p p p p p p p p p p p p p p
the test is usually performed by John. He asks a fellow employee to analyzethe sample for him
p p p p p p p p p p p p p p p p p p
and not divulge the results. This ethical issue concerns:
p p p p p p p p p
a. confidentiality of patient genetic and medical information. p p p p p p
b. a conflict of interest. p p p
c. resource allocation. p
d. diagnostic accuracy. p
