CMS PHARMACOLOGY 2025/2026 QUESTIONS AND
SOLUTIONS MARKED A+
✔✔A nurse is administering donepezil to a client who has Alzheimer's disease. Which of
the following findings should the nurse report to the provider immediately? -
✔✔Dyspnea,
When using the airway, breathing, circulation approach to client care, the nurse should
report the adverse effects of dyspnea, caused by bronchoconstriction, to the provider
first. Bronchoconstriction, dyspepsia, diarrhea, and dizziness are caused by the
increase in acetylcholine levels, which is a primary effect of donepezil.
✔✔A nurse is caring for a client who is taking acetazolamide fr chronic open angle
glaucoma. For which of the following adverse effects should the nurse instruct the client
to monitor and report? - ✔✔Tingling of fingers
The nurse should instruct the client to report the adverse effect of paresthesia, a tingling
sensation in the extremities, when taking acetazolamide.
✔✔A nurse is teaching a client who is to start taking hydrocodone with acetaminophen
tablets for pain. Which of the following information should the nurse include in the
teaching? - ✔✔Decreased respiration might occur
The nurse should instruct the client that hydrocodone with acetaminophen might cause
respiration depression, which is an adverse effect of the medication. The client should
avoid taking over-the-counter medications without consulting their provider to avoid
increased respiratory depression.
✔✔A nurse is providing teaching to a client who has a gastric ulcer and a new
prescription for ranitidine. Which of the following instructions should the nurse include? -
✔✔Report yellowing of the skin.
Famotidine can be hepatotoxic and cause jaundice. The nurse should instruct the client
to monitor for and report yellowing of the skin or eyes to the provider.
✔✔A nurse administers a dose of metformin for a client instead of the prescribed dose
of metoclopramide. Which of the following actions should the nurse take first? -
✔✔Check the client's blood glucose
The first action the nurse should take using the nursing process is to assess the client.
The client is at risk for hypoglycemia. The nurse should monitor the client's blood
glucose and provide the client with a snack to reduce the risk for hypoglycemia.
✔✔A nurse is caring for a 20 year old female client who has a prescription for
isotretinoin for severe nodulocystic acne vulgaris. Before the client can obtain a refill,
, the nurse should advise the client that which of the following tests is required? -
✔✔Pregnancy test
The nurse should instruct the client that isotretinoin has teratogenic effects; therefore,
pregnancy must be ruled out before the client can obtain a refill. The client must provide
two negative pregnancy tests for the initial prescription and one negative test before
monthly refills.
✔✔A nurse is assessing a client who is postoperative following an outpatient endoscopy
procedure using midazolam. The nurse should monitor for which of the following
findings as an indication that the client is ready for discharge? - ✔✔The client's
capnography has returned to baseline
The nurse should identify that the client is ready for discharge when the capnography
level indicates that the gas exchange is adequate
✔✔A nurse receives a verbal order from the provider to administer morphine 5 mg
every 4 hours subcutaneously for severe pain as needed. The nurse should identify
which of the following entries as the correct format for the medication administration
record (MAR)? - ✔✔Morphine 5 mg subcut every 4 hr PRN severe pain
Medication name is spelled out, no abbreviations. No trailing zero that can be mistaken
for 50.
✔✔A nurse is teaching a client about warfarin. The client asks if they can take aspirin
while taking the warfarin. Which of the following responses should the nurse make? -
✔✔Aspirin will increase the risk of bleeding
Aspirin inhibits platelet aggregation and can potentiate the action of the anticoagulant
warfarin. Therefore, the client should avoid taking aspirin because it increases the risk
for bleeding.
✔✔A nurse is caring for a client who is receiving filgrastim. Which of the following
findings should the nurse document to indicate the effectiveness of the therapy? -
✔✔Increased neutrophil count
Filgrastim stimulates the bone marrow to produce neutrophils. For clients receiving
chemotherapy, the risk of infection is minimized.
✔✔A nurse is caring for the parent of a newborn. The parent asks the nurse when their
newborn should receive the first diphtheria, tetanus, and pertussis vaccine (DTaP). The
nurse should instruct the parent that their newborn should receive the immunization at
which of the following ages? - ✔✔2 months
SOLUTIONS MARKED A+
✔✔A nurse is administering donepezil to a client who has Alzheimer's disease. Which of
the following findings should the nurse report to the provider immediately? -
✔✔Dyspnea,
When using the airway, breathing, circulation approach to client care, the nurse should
report the adverse effects of dyspnea, caused by bronchoconstriction, to the provider
first. Bronchoconstriction, dyspepsia, diarrhea, and dizziness are caused by the
increase in acetylcholine levels, which is a primary effect of donepezil.
✔✔A nurse is caring for a client who is taking acetazolamide fr chronic open angle
glaucoma. For which of the following adverse effects should the nurse instruct the client
to monitor and report? - ✔✔Tingling of fingers
The nurse should instruct the client to report the adverse effect of paresthesia, a tingling
sensation in the extremities, when taking acetazolamide.
✔✔A nurse is teaching a client who is to start taking hydrocodone with acetaminophen
tablets for pain. Which of the following information should the nurse include in the
teaching? - ✔✔Decreased respiration might occur
The nurse should instruct the client that hydrocodone with acetaminophen might cause
respiration depression, which is an adverse effect of the medication. The client should
avoid taking over-the-counter medications without consulting their provider to avoid
increased respiratory depression.
✔✔A nurse is providing teaching to a client who has a gastric ulcer and a new
prescription for ranitidine. Which of the following instructions should the nurse include? -
✔✔Report yellowing of the skin.
Famotidine can be hepatotoxic and cause jaundice. The nurse should instruct the client
to monitor for and report yellowing of the skin or eyes to the provider.
✔✔A nurse administers a dose of metformin for a client instead of the prescribed dose
of metoclopramide. Which of the following actions should the nurse take first? -
✔✔Check the client's blood glucose
The first action the nurse should take using the nursing process is to assess the client.
The client is at risk for hypoglycemia. The nurse should monitor the client's blood
glucose and provide the client with a snack to reduce the risk for hypoglycemia.
✔✔A nurse is caring for a 20 year old female client who has a prescription for
isotretinoin for severe nodulocystic acne vulgaris. Before the client can obtain a refill,
, the nurse should advise the client that which of the following tests is required? -
✔✔Pregnancy test
The nurse should instruct the client that isotretinoin has teratogenic effects; therefore,
pregnancy must be ruled out before the client can obtain a refill. The client must provide
two negative pregnancy tests for the initial prescription and one negative test before
monthly refills.
✔✔A nurse is assessing a client who is postoperative following an outpatient endoscopy
procedure using midazolam. The nurse should monitor for which of the following
findings as an indication that the client is ready for discharge? - ✔✔The client's
capnography has returned to baseline
The nurse should identify that the client is ready for discharge when the capnography
level indicates that the gas exchange is adequate
✔✔A nurse receives a verbal order from the provider to administer morphine 5 mg
every 4 hours subcutaneously for severe pain as needed. The nurse should identify
which of the following entries as the correct format for the medication administration
record (MAR)? - ✔✔Morphine 5 mg subcut every 4 hr PRN severe pain
Medication name is spelled out, no abbreviations. No trailing zero that can be mistaken
for 50.
✔✔A nurse is teaching a client about warfarin. The client asks if they can take aspirin
while taking the warfarin. Which of the following responses should the nurse make? -
✔✔Aspirin will increase the risk of bleeding
Aspirin inhibits platelet aggregation and can potentiate the action of the anticoagulant
warfarin. Therefore, the client should avoid taking aspirin because it increases the risk
for bleeding.
✔✔A nurse is caring for a client who is receiving filgrastim. Which of the following
findings should the nurse document to indicate the effectiveness of the therapy? -
✔✔Increased neutrophil count
Filgrastim stimulates the bone marrow to produce neutrophils. For clients receiving
chemotherapy, the risk of infection is minimized.
✔✔A nurse is caring for the parent of a newborn. The parent asks the nurse when their
newborn should receive the first diphtheria, tetanus, and pertussis vaccine (DTaP). The
nurse should instruct the parent that their newborn should receive the immunization at
which of the following ages? - ✔✔2 months
