N3280 Screening Tests and Assessment
2025
Assessment of fetal well-being in 1st trimester - -
-confirm pregnancy
-confirm viability
-determine gestational age
-detect fetal anomalies
Is transvaginal or transabdominal ultrasonography bettwe - -transvaginal has better and
clearer images
Transvaginal ultrasound - --detects gestational sac at 4-5 weeks
-fetal heart activity at 6-7 weeks
-BPD measurement and crown length at 14 weeks predicts EDB within 7-10 days
transabdominal ultrasound - --fetal heart beat at 10-12 weeks
-fetal weight during pregnancy
screening and diagnostic tests for first trimester - --ultrasound
-nuchal translucency
-maternal assays
-chorionic villus sampling
maternal assays - --coombs' test
-cell-free (DNA) screening
nuchal translucency - -measure nuchal folds (accumulation of fluids)
when to screen for nuchal translucency - -between 10-14 weeks
positive nuchal translucency - ->3mm
coombs' test - --Rh incompatibility
-detects other antibodies for incompatibility with maternal antigens
cell-free DNA screening - --fetal Rh status
-fetal gender
newest screening test for noninvasive prenatal genetic diagnosis - -cell free DNA
screening
N3280
, N3280
chorionic villus sampling - --earlier diagnosis and rapid results
-removal of small tissue specimen from fetal portion of placenta (tissue reflects fetus
genetic makeup)
when to do chorionic villus sampling - -between 10-13 weeks
where do chorionic villi originate - -zygote
assessment of fetal well being in 2nd trimester - --establish or confirm dates
-confirm viability
-assess placental location
-assess for fetal anomalies
how to establish or confirm dates - --uniformity of fetal growth
-allows for biometic measurements
-accurately estimate gestational age
screening and diagnostic tests for second trimester - --ultrasound (2D, 3D, 4D, HD)
-maternal assays alpha-fetoprotein
-amniocentesis
-doppler flow studies
-percutaneous umbilical cord sampling
maternal assay quad screen time frame - -15-21 weeks
what does quad screen measure for - -alpha-fetoprotein
hCG
unconjugated estriol
inhibin A
alpha-fetoprotein - -maternal serum levels are screened for neural tube defects
what percent of neural tube defects and abdominal wall defects can be detected early -
-80-85%
when to perform amniocentesis - -15-20 weeks
indications for amniocentesis - --genetic concerned
-women over 35
-family history of chromosomal abnormalities
what does amniocentesis detect - --genetic, metabolic, DNA abnormalities
-can detect neural tube defects
-fetal hemolytic disease
-lung maturity (lamellar body counts, L/S ratio)
N3280