Test bank for Tietz Fundamentals of Clinical Chemistry
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz gbFundamentals gbof gbClinical gbChemistry gband gbMolecular gbDiagnostics gb8th g b Edition gbTest gbBank
Table gbof gbcontents:
I. gbPrinciples gbOf gbLaboratory gbMedicine
Chapter gb1. gbClinical gbChemistry, gbMolecular gbDiagnostics, gband gbLaboratory gbMedicine
Chapter gb2. gbSelection gband gbAnalytical gbEvaluation gbof gbMethods gb— gbWith gbStatistical
gbTechniques
Chapter gb3. gbClinical gbEvaluation gbof gbMethods
Chapter gb4. gbEvidence-Based gbLaboratory gbMedicine
Chapter gb5. gbEstablishment gband gbUse gbof gbReference gbValues
Chapter gb6. gbSpecimen gbCollection, gbProcessing, gband gbOther gbPreanalytical gbVariables
Chapter gb7. gbQuality gbManagement
II. gbAnalytical gbTechniques gbAnd gbInstrumentation
Chapter gb8. gbPrinciples gbof gbBasic gbTechniques gband gbLaboratory gbSafety
Chapter gb9. gbOptical gbTechniques
Chapter gb10. gbElectrochemistry gband gbChemical gbSensors
Chapter gb11. gbElectrophoresis
Chapter gb12. gbChromatography
Chapter gb13. gbMass gbSpectrometry
Chapter gb14. gbEnzyme gband gbRate gbAnalyses
Chapter gb15. gbImmunochemical gbTechniques
Chapter gb16 gbAutomation
Chapter gb17. gbPoint-of-Care gbInstrumentation
III. g b Analytes
Chapter gb18. gbAmino gbAcids, gbPeptides, gband gbProteins
Chapter gb19. gbSerum gbEnzymes
Chapter gb20. gbTumor gbMarkers gband gbCancer gbGenes
Chapter gb21. gbKidney gbFunction gbTests gb— gbCreatinine, gbGFR, gbUrea, gband gbUric gbAcid
Chapter gb22. gbCarbohydrates
Chapter gb23. gbLipids, gbLipoproteins, gbApolipoproteins, gband gbOther gbCardiac gbRisk gbFactors
Chapter gb24. gbElectrolytes gband gbBlood gbGases
Chapter gb25. gbHormones
Chapter gb26. g b Catecholamines gband gbSerotonin
Chapter gb27. g b Vitamins, gbTrace gbElements, gbNutritional gbAssessment
Chapter gb28. gbHemoglobin, gbIron, gband gbBilirubin
Chapter gb29. gbPorphyrins gband gbPorphyrias
Chapter gb30. gbTherapeutic gbDrugs gband gbTheir gbManagement
Chapter gb31. gbClinical gbToxicology
Chapter gb32. g b Toxic gbMetals
IV. g b Pathophysiology
Chapter gb33. gbDiabetes
,Chapter gb34. g b Cardiovascular gbDisease
Chapter gb35. gbKidney gbDisease
Chapter gb36. g b Physiology gband gbDisorders gbof gbWater, gbElectrolyte, gband gbAcid-Base
gbMetabolism
Chapter gb37. gb gbLiver gbDisease
Chapter gb38. g b Gastrointestinal gband gbPancreatic gbDiseases
Chapter gb39. gb gbDisorders gbof gbBone gband gbMineral gbMetabolism
Chapter gb40. gb gbDisorders gbof gbthe gbPituitary gbGland
Chapter gb41. g b Disorders gbof gbthe gbAdrenal gbCortex
Chapter gb42. g b Thyroid gbDisorders
Chapter gb43. g b Reproduction-Related gbDisorders
Chapter gb44. gb gbPregnancy gband gbPrenatal gbTesting
Chapter gb45. g b Newborn gbScreening gband gbInborn gbErrors gbof gbMetabolism
Chapter gb46. gbPharmacogenetics
V. g b Molecular gbDiagnostics
Chapter gb47. gbPrinciples gbof gbMolecular gbBiology
Chapter gb48. gbNucleic gbAcid gbTechniques gband gbApplications
Chapter gb49. gbGenomes gband gbNucleic gbAcid gbAlterations
, Chapter gb01: gbClinical gbChemistry, gbMolecular gbDiagnostics, gband gbLaboratory
gbMedicine gbTestgbBank
MULTIPLE gbCHOICE
1. An gbindividual gbworking gbin gba gbclinical gbchemistry gblaboratory gbis gbmarried gbto gba
gbsales gbrepresentative gbwho gbworks gbfor gba gbcompany gbthat gbsells gbchemistry
gblaboratory gbsupplies. gbWhen gbthe gblaboratory gbmanager gbrequests gba gblist gbof
gbneeded gbsupplies, gbcost gbof gbsupplies, gband gbvendors, gbthis gbindividual gbonly
gbrecommends gbthe gbspouse’s gbcompany gbas gbthe gbvendor. gbThis gbis gbconsidered gbto gbbe
gba(n):
a. accounting gbissue.
b. possible gbconflict gbof gbinterest.
c. maintenance gbof gbconfidentiality gbissue.
d. problem gbwith gbresource gballocation.
ANS: g b B
Concern gbhas gbbeen gbraised gbover gbthe gbinterrelationships gbbetween gbpractitioners gbin
gbthe gbmedical gbfieldgband gbcommercial gbsuppliers gbof gbdrugs, gbdevices, gbequipment,
gbetc., gbto gbthe gbmedical gbprofession.
Similarly, gbrelationships gbhave gbbeen gbscrutinized gbbetween gbclinical gblaboratorians gband
gbmanufacturers gband gbproviders gbof gbdiagnostic gbequipment gband gbsupplies. gbThese
gbconcerns gbled gbthe gbNational gbInstitutes gbof gbHealth gb(NIH) gbin gb1995 gbto gbrequire
gbofficial gbinstitutional gbreview gbof gbfinancial gbdisclosure gbby gbresearchers gband
gbmanagement gbof gbsituations gbin gbwhich gbdisclosure gbindicates gbpotentialgbconflicts gbof
gbinterest.
DIF: 1 REF: gb gb gbPage gb4-5 OBJ: g b 6 gb| gb7
2. A gbpatient gbvisits gbher gbphysician gbstating gbthat gbher gbprescribed gbpainkiller gbis gbnot
gbworking gbto gbreduce gbthe gbpain gbfollowing gbher gbrecent gbsurgery. gbA gbfriend gbof gbthe
gbpatient gbclaims gbthat gbthe gbsame gbpainkillergb“worked gbwonders” gbto gbreduce gbher
gbpain gbafter gbthe gbsame gbsurgery. gbThe gbphysician gbstates gbthat gbthe gbdifference gbin
gbthe gbeffect gbof gbthe gbdrug gbmight gbbe gbcaused gbby , gbwhich gbis gbstudied gbin
gbpharmacogenetics.
a. epidemiology
b. an gbinherited gbdisease
c. a gbconflict gbof gbinterest
d. a gbgenetic gbvariation gbin gbdrug-metabolizing gbenzymes
ANS: g b D
Pharmacogenetics gbis gbthe gbstudy gbof gbthe gbgenetic gbvariation gbof gbdrug
gbmetabolism gbbetweengbindividuals.
DIF: 1 REF: gb gb gbPage gb3 OBJ: g b 1
3. John gbworks gbin gba gbmolecular gbdiagnostics gblaboratory gband gbreceives gba gbblood
gbsample gbthat gbhas gbthe gbname gbof gba gbclose gbfriend gbprinted gbon gbthe gbbar-coded
gblabel. gbThe gbgenetic gbtest gbthat gbis gbordered gbon gbthegbfriend’s gbsample gbwould
gbprovide gbdiagnostic gbinformation gbabout gba gbdisorder gbthat gbhas gba gbpoor
gbprognosis, gband gbthe gbtest gbis gbusually gbperformed gbby gbJohn. gbHe gbasks gba gbfellow
gbemployee gbto gbanalyzegbthe gbsample gbfor gbhim gband gbnot gbdivulge gbthe gbresults. gbThis
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz gbFundamentals gbof gbClinical gbChemistry gband gbMolecular gbDiagnostics gb8th g b Edition gbTest gbBank
Table gbof gbcontents:
I. gbPrinciples gbOf gbLaboratory gbMedicine
Chapter gb1. gbClinical gbChemistry, gbMolecular gbDiagnostics, gband gbLaboratory gbMedicine
Chapter gb2. gbSelection gband gbAnalytical gbEvaluation gbof gbMethods gb— gbWith gbStatistical
gbTechniques
Chapter gb3. gbClinical gbEvaluation gbof gbMethods
Chapter gb4. gbEvidence-Based gbLaboratory gbMedicine
Chapter gb5. gbEstablishment gband gbUse gbof gbReference gbValues
Chapter gb6. gbSpecimen gbCollection, gbProcessing, gband gbOther gbPreanalytical gbVariables
Chapter gb7. gbQuality gbManagement
II. gbAnalytical gbTechniques gbAnd gbInstrumentation
Chapter gb8. gbPrinciples gbof gbBasic gbTechniques gband gbLaboratory gbSafety
Chapter gb9. gbOptical gbTechniques
Chapter gb10. gbElectrochemistry gband gbChemical gbSensors
Chapter gb11. gbElectrophoresis
Chapter gb12. gbChromatography
Chapter gb13. gbMass gbSpectrometry
Chapter gb14. gbEnzyme gband gbRate gbAnalyses
Chapter gb15. gbImmunochemical gbTechniques
Chapter gb16 gbAutomation
Chapter gb17. gbPoint-of-Care gbInstrumentation
III. g b Analytes
Chapter gb18. gbAmino gbAcids, gbPeptides, gband gbProteins
Chapter gb19. gbSerum gbEnzymes
Chapter gb20. gbTumor gbMarkers gband gbCancer gbGenes
Chapter gb21. gbKidney gbFunction gbTests gb— gbCreatinine, gbGFR, gbUrea, gband gbUric gbAcid
Chapter gb22. gbCarbohydrates
Chapter gb23. gbLipids, gbLipoproteins, gbApolipoproteins, gband gbOther gbCardiac gbRisk gbFactors
Chapter gb24. gbElectrolytes gband gbBlood gbGases
Chapter gb25. gbHormones
Chapter gb26. g b Catecholamines gband gbSerotonin
Chapter gb27. g b Vitamins, gbTrace gbElements, gbNutritional gbAssessment
Chapter gb28. gbHemoglobin, gbIron, gband gbBilirubin
Chapter gb29. gbPorphyrins gband gbPorphyrias
Chapter gb30. gbTherapeutic gbDrugs gband gbTheir gbManagement
Chapter gb31. gbClinical gbToxicology
Chapter gb32. g b Toxic gbMetals
IV. g b Pathophysiology
Chapter gb33. gbDiabetes
,Chapter gb34. g b Cardiovascular gbDisease
Chapter gb35. gbKidney gbDisease
Chapter gb36. g b Physiology gband gbDisorders gbof gbWater, gbElectrolyte, gband gbAcid-Base
gbMetabolism
Chapter gb37. gb gbLiver gbDisease
Chapter gb38. g b Gastrointestinal gband gbPancreatic gbDiseases
Chapter gb39. gb gbDisorders gbof gbBone gband gbMineral gbMetabolism
Chapter gb40. gb gbDisorders gbof gbthe gbPituitary gbGland
Chapter gb41. g b Disorders gbof gbthe gbAdrenal gbCortex
Chapter gb42. g b Thyroid gbDisorders
Chapter gb43. g b Reproduction-Related gbDisorders
Chapter gb44. gb gbPregnancy gband gbPrenatal gbTesting
Chapter gb45. g b Newborn gbScreening gband gbInborn gbErrors gbof gbMetabolism
Chapter gb46. gbPharmacogenetics
V. g b Molecular gbDiagnostics
Chapter gb47. gbPrinciples gbof gbMolecular gbBiology
Chapter gb48. gbNucleic gbAcid gbTechniques gband gbApplications
Chapter gb49. gbGenomes gband gbNucleic gbAcid gbAlterations
, Chapter gb01: gbClinical gbChemistry, gbMolecular gbDiagnostics, gband gbLaboratory
gbMedicine gbTestgbBank
MULTIPLE gbCHOICE
1. An gbindividual gbworking gbin gba gbclinical gbchemistry gblaboratory gbis gbmarried gbto gba
gbsales gbrepresentative gbwho gbworks gbfor gba gbcompany gbthat gbsells gbchemistry
gblaboratory gbsupplies. gbWhen gbthe gblaboratory gbmanager gbrequests gba gblist gbof
gbneeded gbsupplies, gbcost gbof gbsupplies, gband gbvendors, gbthis gbindividual gbonly
gbrecommends gbthe gbspouse’s gbcompany gbas gbthe gbvendor. gbThis gbis gbconsidered gbto gbbe
gba(n):
a. accounting gbissue.
b. possible gbconflict gbof gbinterest.
c. maintenance gbof gbconfidentiality gbissue.
d. problem gbwith gbresource gballocation.
ANS: g b B
Concern gbhas gbbeen gbraised gbover gbthe gbinterrelationships gbbetween gbpractitioners gbin
gbthe gbmedical gbfieldgband gbcommercial gbsuppliers gbof gbdrugs, gbdevices, gbequipment,
gbetc., gbto gbthe gbmedical gbprofession.
Similarly, gbrelationships gbhave gbbeen gbscrutinized gbbetween gbclinical gblaboratorians gband
gbmanufacturers gband gbproviders gbof gbdiagnostic gbequipment gband gbsupplies. gbThese
gbconcerns gbled gbthe gbNational gbInstitutes gbof gbHealth gb(NIH) gbin gb1995 gbto gbrequire
gbofficial gbinstitutional gbreview gbof gbfinancial gbdisclosure gbby gbresearchers gband
gbmanagement gbof gbsituations gbin gbwhich gbdisclosure gbindicates gbpotentialgbconflicts gbof
gbinterest.
DIF: 1 REF: gb gb gbPage gb4-5 OBJ: g b 6 gb| gb7
2. A gbpatient gbvisits gbher gbphysician gbstating gbthat gbher gbprescribed gbpainkiller gbis gbnot
gbworking gbto gbreduce gbthe gbpain gbfollowing gbher gbrecent gbsurgery. gbA gbfriend gbof gbthe
gbpatient gbclaims gbthat gbthe gbsame gbpainkillergb“worked gbwonders” gbto gbreduce gbher
gbpain gbafter gbthe gbsame gbsurgery. gbThe gbphysician gbstates gbthat gbthe gbdifference gbin
gbthe gbeffect gbof gbthe gbdrug gbmight gbbe gbcaused gbby , gbwhich gbis gbstudied gbin
gbpharmacogenetics.
a. epidemiology
b. an gbinherited gbdisease
c. a gbconflict gbof gbinterest
d. a gbgenetic gbvariation gbin gbdrug-metabolizing gbenzymes
ANS: g b D
Pharmacogenetics gbis gbthe gbstudy gbof gbthe gbgenetic gbvariation gbof gbdrug
gbmetabolism gbbetweengbindividuals.
DIF: 1 REF: gb gb gbPage gb3 OBJ: g b 1
3. John gbworks gbin gba gbmolecular gbdiagnostics gblaboratory gband gbreceives gba gbblood
gbsample gbthat gbhas gbthe gbname gbof gba gbclose gbfriend gbprinted gbon gbthe gbbar-coded
gblabel. gbThe gbgenetic gbtest gbthat gbis gbordered gbon gbthegbfriend’s gbsample gbwould
gbprovide gbdiagnostic gbinformation gbabout gba gbdisorder gbthat gbhas gba gbpoor
gbprognosis, gband gbthe gbtest gbis gbusually gbperformed gbby gbJohn. gbHe gbasks gba gbfellow
gbemployee gbto gbanalyzegbthe gbsample gbfor gbhim gband gbnot gbdivulge gbthe gbresults. gbThis
