Hematology ASCP BOC

Hematology ASCP BOC The following are compounds formed in the synthesis of heme: 1 coproporphyrinogen 2 porphobilinogen 3 uroporphyrinogen 4 protoporphyrinogen Which of the following responses lists these compounds in the order in which they are formed? - 2, 3, 1, 4 The majority of the iron in an adult is found as a constituent of: - hemoglobin In order for hemoglobin to combine reversibly with oxygen, the iron must be: - in the ferrous state Which description best fits the Donath-Landsteiner antibody? - IgG biphasic hemolysin the abnormal erythrocyte in the center of this image (arrow) may result from which of the following processes? - deficiencies of cellular membrane proteins what is the composition of the inclusion seen in this RBC? - DNA Which of the following ions is bound to hemoglobin in methemoglobin? - Fe3+ An increased amount of cytoplasmic basophilia in a blood cell indicates: - decreased cytoplasmic maturation Specific (secondary) granules of the neutrophilic granulocyte: - appear first at the myelocyte stage In normal adult bone marrow, the most common granulocyte is the? - metamyelocyte Pluripotent hematopoietic stem cells are capable of producing: - lymphoid and myeloid stem cells Which of the following cytokines is most responsible for eosinophil differentiation and release from the bone marrow? - IL-5 Auer rods are characterized as: - DNA precipitates