Test Bank For Introductory Clinical Pharmacology
12th Edition By Susan Ford
Chapter 1 - 54 | Complete
, Introductory Clinical Pharmacology 12th Edition Susan Ford Nursing Test Bank
Contents
Unit 1 Nursing Foundation of Clinical Pharmacology
1 General Principles of Pharmacology
2 Administration of Drugs
3 Making Drug Dosing Safer
4 The Nursing Process
5 Client and Family Teaching
Unit 2 Drugs Used to Fight Infections
6 Antibacterial Drugs: Sulfonamides
7 Antibacterial Drugs That Disrupt the Bacterial Cell Wall
8 Antibacterial Drugs That Interfere With Protein Synthesis
9 Antibacterial Drugs That Interfere With DNA/RNA Synthesis
10 Antitubercular Drugs
11 Antiviral Drugs
12 Antifungal and Antiparasitic Drugs
Unit 3 Drugs Used to Manage Pain
13 Nonopioid Analgesics: Salicylates and Nonsalicylates
14 Nonopioid Analgesics: Nonsteroidal Anti-inflammatory Drugs and Migraine Headache
Medications
15 Opioid Analgesics and Antagonists
16 Anesthetic Drugs
Unit 4 Drugs That Affect the Central Nervous System
17 Central Nervous System Stimulants
18 Antidementia Drugs
19 Antianxiety Drugs
20 Sedatives and Hypnotics
21 Antidepressant Drugs
22 Antipsychotic Drug
Unit 5 Drugs That Affect the Peripheral Nervous System
23 Adrenergic Drugs
24 Adrenergic Blocking Drugs
25 Cholinergic Drugs
26 Cholinergic Blocking Drugs
Unit 6 Drugs That Affect the Neuromuscular System
27 Antiparkinson Drugs
28 Antiepileptics
,29 Skeletal Muscle, Bone, and Joint Disorder Drugs
Unit 7 Drugs That Affect the Respiratory System
30 Upper Respiratory System Drugs
31 Lower Respiratory System Drugs
Unit 8 Drugs That Affect the Cardiovascular System
32 Diuretics
33 Antihyperlipidemic Drugs
34 Antihypertensive Drugs
35 Antianginal and Vasodilating Drugs
36 Anticoagulant and Thrombolytic Drugs
37 Cardiotonic and Antiarrhythmic Drugs
Unit 9 Drugs That Affect the Gastrointestinal System
38 Upper Gastrointestinal System Drugs
39 Lower Gastrointestinal System Drug
Unit 10 Drugs That Affect the Endocrine System
40 Antidiabetic Drugs
41 Pituitary and Adrenocortical Hormones
42 Thyroid and Antithyroid Drugs
43 Male and Female Hormones
44 Uterine Drugs
Unit 11 Drugs That Affect the Urinary System
45 Menopause and Andropause Drugs
46 Urinary Tract Anti-Infectives and Other Urinary Drugs
Unit 12 Drugs That Affect the Immune System
47 Vaccines
48 Immunostimulants and Immunomodulators
49 Immune Blockers
Unit 13 Drugs That Fight Cancer
50 Traditional Chemotherapy
51 Immune Modulating Therapies
Unit 14 Drugs That Affect Other Body Systems
52 Skin Disorder Topical Drugs
53 Otic and Ophthalmic Preparations
54 Fluids, Electrolytes, and Parenteral Therapy
,1 General Principles of Pharmacology
A nursing instructor is preparing a teaching plan for a group of nursing students about
pharmacology. When describing this topic, the instructor would focus the discussion on
which of the following as an essential aspect?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
ANSWER: C
Feedback:
Pharmacology is the study of drugs and their action on living organisms. Thus, an
essential aspect of pharmacology is drug action. An understanding of the drug name,
drug class, and drug source is important, but the most critical aspect related to
pharmacology is how the drug acts in the body.
2. A nursing student is preparing to administer a prescribed drug to a patient. The student
reviews information about the drug and its actions. Which of the following would be the
best choice for obtaining this information? Select all that apply.
A) Nursing instructor
B) Nurse assigned to the patient
C) Clinical drug reference
D) Prescribing health care provider
E) Clinical pharmacist
ANSWER: C, E
Feedback:
Although the nursing student can ask the nursing instructor, the nurse assigned to the
patient, and the prescribing health care provider for information about the drug, the best
choices for drug information would include an appropriate drug reference and the
clinical pharmacist.
3. When describing the various types of medications to a group of nursing students, a
nursing instructor would identify which of the following as a source for deriving
medications? Select all that apply.
A) Plants
B) Synthetic sources
C) Mold
D) Minerals
E) Animals
ANSWER: A, B,
C, D, EFeedback:
Medications are derived from natural sources, for example, plants, molds, minerals, and
animals, as well as created synthetically in a laboratory.
,4. Which of the following names may be assigned to a drug during the process of
development? Select all that apply.
A) Chemical name
B) Official name
C) Pharmacologic name
D) Trade name
E) Nonproprietary name
ANSWER: A, B, D, E
Feedback:
Throughout the process of development, drugs may have several names assigned to
them including a chemical name, a generic (nonproprietary) name, an official name, and
a trade or brand name.
5. A drug may be classified by which of the following? Select all that apply.
A) The chemical type of the drug's active ingredient
B) The way the drug is used to treat a specific condition
C) The generic name of the drug
D) The trade name of the drug
E) The nonproprietary name of the drug
ANSWER: A, B
Feedback:
A drug may be classified by the chemical type of the active ingredient or by the way it is
used to treat a particular condition. Generic, trade, and nonproprietary refer to how a
drug is named.
6. A group of nursing students are reviewing information about the process of drug
development in the United States. The students demonstrate understanding of this
process when they identify that which of the following categories are assigned by the
Food and Drug Administration to newly approved drugs? Select all that apply.
A) Metabolite
B) Noncontrolled substance
C) Prescription
D) Nonprescription
E) Controlled substance
ANSWER: C, D, E
Feedback:
Once drugs are approved for use, the FDA assigns the drug to one of the following
categories: prescription, nonprescription, or controlled substance. Metabolite refers to
the inactive form of the drug. Noncontrolled substance is a term that is not used.
,7. Which of the following would be most important for the nurse to do to ensure the safe
use of prescription drugs in the institutional setting? Select all that apply.
A) Administering drugs
B) Monitoring clients for drug effects
C) Prescribing drugs
D) Evaluating clients for toxic effects
E) Educating clients/caregivers about drugs
ANSWER: A, B, D, E
Feedback:
In the institutional setting, the nurse's role to ensure safe use of prescription drugs
includes administering drugs, monitoring drug effects, evaluating for toxic effects, and
educating clients and caregivers about drugs.
8. The nurse is helping a client review a prescription from the health care provider. When
examining the prescription, which of the following would the nurse expect to find
documented? Select all that apply.
A) Name of the drug
B) Dosage of the drug
C) Route of drug administration
D) Times of drug administration
E) Licensed prescriber's signature
ANSWER: A, B, C, D, E
Feedback:
The prescription must contain the client's name, the name of the drug, the dosage, the
method and times of administration, and the signature of the licensed health care
provider prescribing the drug.
9. After teaching a group of nursing students about nonprescription drugs, the nursing
instructor determines that the teaching was successful when the students identify which
of the following? Select all that apply.
A) They require a licensed health care provider's signature.
B) They are referred to as over-the-counter drugs.
C) They can be taken without risk to the client.
D) They have certain labeling requirements.
E) They should be taken only as directed on the label.
ANSWER: B, D, E
Feedback:
Nonprescription drugs are often referred to as over-the-counter (OTC) drugs. They do
not require a prescription (a licensed health care provider's signature) but do not come
without risk to the client. The federal government has imposed labeling requirements of
OTC drugs and they should only be taken as directed on the label unless under the
supervision of a health care provider.
,10. A nursing student is reviewing information about the Controlled Substances Act of
1970. The student would expect to find which of the following as being regulated for
drugs classified as controlled substances? Select all that apply.
A) Manufacturing
B) Elimination
C) Distribution
D) Formulation
E) Dispensing
ANSWER: A, C,
E Feedback:
The Controlled Substances Act of 1970 regulates the manufacture, distribution, and
dispensing of drugs classified as controlled substances. Elimination refers to the
excretion of drugs from the body, a pharmacokinetic activity. The act does not address
formulation of the drug.
11. When reviewing information about the Orphan Drug Program, which of the following
would the nurse expect to find? Select all that apply.
A) The program encourages the development and marketing of products to treat rare
diseases.
B) The program grants provisional approval with a written commitment from the
drug company to formally demonstrate client benefits.
C) The program provides for incentives, such as research grants, protocol assistance,
and special tax credits, to develop products to treat rare diseases.
D) The program grants 7 years of exclusive marketing rights to the manufacturer if
approved.
E) The program accelerates approval of drugs based on preliminary evidence before
formal demonstration of client benefits.
ANSWER: A, C, D
Feedback:
The Orphan Drug Program encourages the development and marketing of products used
to treat rare diseases. The program provides incentives to encourage manufacturers to
develop orphan drugs, and if approved, the manufacturer has 7 years of exclusive
marketing rights. Accelerated programs involve provisional approval and approval
based on preliminary evidence.
,12. After tteaching ta tgroup tof tnursing tstudents tabout tpharmacokinetics, tthe tinstructor
tdetermines tthat tthe tteaching twas tsuccessful twhen tthe tstudents tidentify twhich tof
tthetfollowing tas ta tphase? tSelect tall tthat tapply.
A) Absorption
B) Distribution
C) Administration
D) Metabolism
E) Excretion
tANSWER: tA,
tB, tD,
tEtFeedback:
The tpharmacokinetic tphases tare tabsorption, tdistribution, tmetabolism, tand
texcretion.tThe tacronym tADME tis ta thelpful tway tto tremember tthe tpharmacokinetic
tphases.
13. A tnurse tis tpreparing ta tteaching tplan tfor ta tclient twho tis tprescribed tan toral
tmedication.tAs tpart tof tthe tplan, tthe tnurse texpects tto tdescribe tthe timportance tof
tabsorption. tThe tnurse twould tintegrate tknowledge tof twhich tof tthe tfollowing tas ta
tmechanism tfor tabsorption tin tthe tgastrointestinal ttract? tSelect tall tthat tapply.
A) Active ttransport
B) Transposition
C) Passive ttransport
D) Endocytosis
E) Pinocytosist
ANSWER: t A,
tC, tE tFeedback:
During tabsorption, tthe tdrug tparticles tin tthe tGI ttract tare tmoved tinto tthe tbody tfluids
tviatactive ttransport, tpassive ttransport, tand tpinocytosis.
14. After tteaching ta tgroup tof tnursing tstudents tabout tthe thalf-life tof ta tdrug, tthe
tinstructortdetermines tthe tneed tfor tadditional tteaching twhen tthe tstudents tidentify
twhich tof tthe tfollowing tas ttrue? tSelect tall tthat tapply:
A) Half-life tcan tbe tdecreased tin tclients twith trenal tdisease.
B) Half-life tcan thelp tdetermine tdosing tfrequency.
C) Half-life tdoes tnot tchange tthroughout ta tclient's tlife.
D) Liver tdisease tcan tincrease thalf-life.
E) Half-life tis tthe tmeasure tof tthe trate tat twhich tdrugs tare tremoved tfrom tthe
tbody.tANSWER: t A, tC
Feedback:
Half-life tis tthe tmeasure tof tthe trate tat twhich tdrugs tare tremoved tfrom tthe tbody, tand
tanytdifficulty tin texcreting ta tdrug tincreases thalf-life, tincluding tliver tor tkidney tdisease
tor tadvanced tage.
,15. A tnurse tis tassessing ta tclient tafter tadministering ta tprescribed tmedication. tWhich tof
tthetfollowing twould talert tthe tnurse tto tsuspect tthat tthe tclient tis tdeveloping
tanaphylactic tshock? tSelect tall tthat tapply.
A) Bradycardia
B) Hypertension
C) Dyspnea
D) Urticaria
E) Angioedemat
ANSWER: t C, tD,
tE tFeedback:
The tsymptoms tof tanaphylactic tshock tare tdyspnea, tfeeling tof tfullness tin tthe tthroat,
tcough, twheezing, textremely tlow tblood tpressure, ttachycardia t(heart trate t>100 tbpm),
tpalpitations, tsyncope, tcardiac tarrest, turticaria, tangioedema, tpruritus, tsweating,
tnausea,tvomiting, tand tabdominal tpain.
16. Which tof tthe tfollowing twould tthe tnurse tidentify tas ta tfactor tthat talters tdrug tresponse
tintchildren tand tinfants? tSelect tall tthat tapply.
A) Slower tgastric temptying
B) Greater tsurface tarea
C) Less tprotein tbinding
D) Decreased tbody twater tcontent
E) Less tcutaneous
tfattANSWER: t A, tB, tC,
tE tFeedback:
Children tand tinfants tare tnot tsmall tadults; ttherefore, tthey thave taltered
tpharmacokinetics.tFactors tthat talter tpharmacokinetics tin tchildren tinclude tslower
tgastric temptying, tless tcutaneous tfat, tgreater tsurface tarea, tincreased tbody twater
tcontent, tless tprotein tbinding, tand timmature thepatic tand trenal tfunction.
17. The tFDA testablished ta tsafety tinformation tand tadverse tevents treporting tprogram
tcalled tMedWatch. tWhich tindividuals tcan taccess tthe tMedWatch twebsite tto tobtain
tsafety talertston tdrugs, tdevices, tor tdietary tsupplements? tSelect tall tthat tapply.
A) Physicians
B) Nurses
C) Patients
D) Pharmacists
E) Caregivers
tANSWER: tA, tB,
tC, tD, tEtFeedback:
Anyone tcan taccess tthe tMedWatch twebsite tto tobtain tsafety talerts ton tdrugs, tdevices,
tortdietary tsupplements.
, 18. A tnurse tis tpreparing tto tadminister ta tprescribed tmedication tto ta tclient. tThe tnurse
tintegrates tknowledge tof twhich tof tthe tfollowing tas ta tpossible tfactor tthat tcould
tinfluencetthe tdrug tresponse? tSelect tall tthat tapply.
A) Age
B) Polypharmacy
C) Weight
D) Sex
E) Disease
ANSWER: t A, tB, tC, tD, tE
Feedback:
Drug tresponse tcan tbe tinfluenced tby tthe tfollowing tfactors: tage, tpolypharmacy,
tweight,tsex, tdisease, tand tgenetics.
19. A tnurse tis tassessing ta tclient tand tnotes tthat tthe tclient thas tdeveloped tswelling tof tthe
teyelids tand tlips tafter tadministration tof ta tprescribed tmedication. tThe tnurse tinterprets
tthistfinding tas tspecifically tindicating twhich tof tthe tfollowing?
A) Mild tallergic treaction
B) Anaphylactic tshock
C) Angioedema
D) Drug
tidiosyncrasytANSWER:
tC
Feedback:
Angioedema tis ta ttype tof tallergic tdrug treaction tmanifested tby tthe tcollection tof tfluid tin
tthe tsubcutaneous ttissues, tmost tcommonly taffecting tthe teyelids, tlips, tmouth, tand
tthroat.tAllergic treactions tcan tbe tmanifested tby ta twide trange tof tsigns tand tsymptoms
tsuch tas titching, trashes, tand thives. tAnaphylactic tshock tis ta tserious tallergic treaction
tthat trequirestimmediate tmedical tattention. tDrug tidiosyncrasy tdescribes tany tunusual tor
tabnormal treaction tto ta tdrug, tone tthat tis tdifferent tfrom tthe tone tnormally texpected.
20. Which tof tthe tfollowing tis ttrue tregarding tthe tDietary tSupplement tHealth tand
tEducationtAct t(DSHEA)? tSelect tall tthat tapply.
A) The tact tallows tfor tDEA tenforcement tof tthe tact.
B) The tact tgives tthe tFDA tpower tto tenforce tthe tlaws tgoverned tby tthe tact.
C) The tact tpermits tgeneral thealth tclaims.
D) The tact tpermits tcurative thealth tclaims.
E) The tact tdefines tspecific tsubstances tas t“dietary
tsupplements.”tANSWER: t B, tC, tE
Feedback:
The tDSHEA tdefines tsubstances tsuch tas therbs, tvitamins, tminerals, tamino tacids, tand
tother tnatural tsubstances tas t“dietary tsupplements” tand tpermits tgeneral thealth tclaims
tastlong tas tthe tlabel talso thas ta tdisclaimer tstating tthat tthe tsupplements tare tnot
tapproved tbytthe tFDA tand tare tnot tintended tto tdiagnose, ttreat, tcure, tor tprevent tany
tdisease. tThe tact tgives tthe tFDA tthe tpower tto tenforce tthe tlaws tgoverned tby tthe tact.
12th Edition By Susan Ford
Chapter 1 - 54 | Complete
, Introductory Clinical Pharmacology 12th Edition Susan Ford Nursing Test Bank
Contents
Unit 1 Nursing Foundation of Clinical Pharmacology
1 General Principles of Pharmacology
2 Administration of Drugs
3 Making Drug Dosing Safer
4 The Nursing Process
5 Client and Family Teaching
Unit 2 Drugs Used to Fight Infections
6 Antibacterial Drugs: Sulfonamides
7 Antibacterial Drugs That Disrupt the Bacterial Cell Wall
8 Antibacterial Drugs That Interfere With Protein Synthesis
9 Antibacterial Drugs That Interfere With DNA/RNA Synthesis
10 Antitubercular Drugs
11 Antiviral Drugs
12 Antifungal and Antiparasitic Drugs
Unit 3 Drugs Used to Manage Pain
13 Nonopioid Analgesics: Salicylates and Nonsalicylates
14 Nonopioid Analgesics: Nonsteroidal Anti-inflammatory Drugs and Migraine Headache
Medications
15 Opioid Analgesics and Antagonists
16 Anesthetic Drugs
Unit 4 Drugs That Affect the Central Nervous System
17 Central Nervous System Stimulants
18 Antidementia Drugs
19 Antianxiety Drugs
20 Sedatives and Hypnotics
21 Antidepressant Drugs
22 Antipsychotic Drug
Unit 5 Drugs That Affect the Peripheral Nervous System
23 Adrenergic Drugs
24 Adrenergic Blocking Drugs
25 Cholinergic Drugs
26 Cholinergic Blocking Drugs
Unit 6 Drugs That Affect the Neuromuscular System
27 Antiparkinson Drugs
28 Antiepileptics
,29 Skeletal Muscle, Bone, and Joint Disorder Drugs
Unit 7 Drugs That Affect the Respiratory System
30 Upper Respiratory System Drugs
31 Lower Respiratory System Drugs
Unit 8 Drugs That Affect the Cardiovascular System
32 Diuretics
33 Antihyperlipidemic Drugs
34 Antihypertensive Drugs
35 Antianginal and Vasodilating Drugs
36 Anticoagulant and Thrombolytic Drugs
37 Cardiotonic and Antiarrhythmic Drugs
Unit 9 Drugs That Affect the Gastrointestinal System
38 Upper Gastrointestinal System Drugs
39 Lower Gastrointestinal System Drug
Unit 10 Drugs That Affect the Endocrine System
40 Antidiabetic Drugs
41 Pituitary and Adrenocortical Hormones
42 Thyroid and Antithyroid Drugs
43 Male and Female Hormones
44 Uterine Drugs
Unit 11 Drugs That Affect the Urinary System
45 Menopause and Andropause Drugs
46 Urinary Tract Anti-Infectives and Other Urinary Drugs
Unit 12 Drugs That Affect the Immune System
47 Vaccines
48 Immunostimulants and Immunomodulators
49 Immune Blockers
Unit 13 Drugs That Fight Cancer
50 Traditional Chemotherapy
51 Immune Modulating Therapies
Unit 14 Drugs That Affect Other Body Systems
52 Skin Disorder Topical Drugs
53 Otic and Ophthalmic Preparations
54 Fluids, Electrolytes, and Parenteral Therapy
,1 General Principles of Pharmacology
A nursing instructor is preparing a teaching plan for a group of nursing students about
pharmacology. When describing this topic, the instructor would focus the discussion on
which of the following as an essential aspect?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
ANSWER: C
Feedback:
Pharmacology is the study of drugs and their action on living organisms. Thus, an
essential aspect of pharmacology is drug action. An understanding of the drug name,
drug class, and drug source is important, but the most critical aspect related to
pharmacology is how the drug acts in the body.
2. A nursing student is preparing to administer a prescribed drug to a patient. The student
reviews information about the drug and its actions. Which of the following would be the
best choice for obtaining this information? Select all that apply.
A) Nursing instructor
B) Nurse assigned to the patient
C) Clinical drug reference
D) Prescribing health care provider
E) Clinical pharmacist
ANSWER: C, E
Feedback:
Although the nursing student can ask the nursing instructor, the nurse assigned to the
patient, and the prescribing health care provider for information about the drug, the best
choices for drug information would include an appropriate drug reference and the
clinical pharmacist.
3. When describing the various types of medications to a group of nursing students, a
nursing instructor would identify which of the following as a source for deriving
medications? Select all that apply.
A) Plants
B) Synthetic sources
C) Mold
D) Minerals
E) Animals
ANSWER: A, B,
C, D, EFeedback:
Medications are derived from natural sources, for example, plants, molds, minerals, and
animals, as well as created synthetically in a laboratory.
,4. Which of the following names may be assigned to a drug during the process of
development? Select all that apply.
A) Chemical name
B) Official name
C) Pharmacologic name
D) Trade name
E) Nonproprietary name
ANSWER: A, B, D, E
Feedback:
Throughout the process of development, drugs may have several names assigned to
them including a chemical name, a generic (nonproprietary) name, an official name, and
a trade or brand name.
5. A drug may be classified by which of the following? Select all that apply.
A) The chemical type of the drug's active ingredient
B) The way the drug is used to treat a specific condition
C) The generic name of the drug
D) The trade name of the drug
E) The nonproprietary name of the drug
ANSWER: A, B
Feedback:
A drug may be classified by the chemical type of the active ingredient or by the way it is
used to treat a particular condition. Generic, trade, and nonproprietary refer to how a
drug is named.
6. A group of nursing students are reviewing information about the process of drug
development in the United States. The students demonstrate understanding of this
process when they identify that which of the following categories are assigned by the
Food and Drug Administration to newly approved drugs? Select all that apply.
A) Metabolite
B) Noncontrolled substance
C) Prescription
D) Nonprescription
E) Controlled substance
ANSWER: C, D, E
Feedback:
Once drugs are approved for use, the FDA assigns the drug to one of the following
categories: prescription, nonprescription, or controlled substance. Metabolite refers to
the inactive form of the drug. Noncontrolled substance is a term that is not used.
,7. Which of the following would be most important for the nurse to do to ensure the safe
use of prescription drugs in the institutional setting? Select all that apply.
A) Administering drugs
B) Monitoring clients for drug effects
C) Prescribing drugs
D) Evaluating clients for toxic effects
E) Educating clients/caregivers about drugs
ANSWER: A, B, D, E
Feedback:
In the institutional setting, the nurse's role to ensure safe use of prescription drugs
includes administering drugs, monitoring drug effects, evaluating for toxic effects, and
educating clients and caregivers about drugs.
8. The nurse is helping a client review a prescription from the health care provider. When
examining the prescription, which of the following would the nurse expect to find
documented? Select all that apply.
A) Name of the drug
B) Dosage of the drug
C) Route of drug administration
D) Times of drug administration
E) Licensed prescriber's signature
ANSWER: A, B, C, D, E
Feedback:
The prescription must contain the client's name, the name of the drug, the dosage, the
method and times of administration, and the signature of the licensed health care
provider prescribing the drug.
9. After teaching a group of nursing students about nonprescription drugs, the nursing
instructor determines that the teaching was successful when the students identify which
of the following? Select all that apply.
A) They require a licensed health care provider's signature.
B) They are referred to as over-the-counter drugs.
C) They can be taken without risk to the client.
D) They have certain labeling requirements.
E) They should be taken only as directed on the label.
ANSWER: B, D, E
Feedback:
Nonprescription drugs are often referred to as over-the-counter (OTC) drugs. They do
not require a prescription (a licensed health care provider's signature) but do not come
without risk to the client. The federal government has imposed labeling requirements of
OTC drugs and they should only be taken as directed on the label unless under the
supervision of a health care provider.
,10. A nursing student is reviewing information about the Controlled Substances Act of
1970. The student would expect to find which of the following as being regulated for
drugs classified as controlled substances? Select all that apply.
A) Manufacturing
B) Elimination
C) Distribution
D) Formulation
E) Dispensing
ANSWER: A, C,
E Feedback:
The Controlled Substances Act of 1970 regulates the manufacture, distribution, and
dispensing of drugs classified as controlled substances. Elimination refers to the
excretion of drugs from the body, a pharmacokinetic activity. The act does not address
formulation of the drug.
11. When reviewing information about the Orphan Drug Program, which of the following
would the nurse expect to find? Select all that apply.
A) The program encourages the development and marketing of products to treat rare
diseases.
B) The program grants provisional approval with a written commitment from the
drug company to formally demonstrate client benefits.
C) The program provides for incentives, such as research grants, protocol assistance,
and special tax credits, to develop products to treat rare diseases.
D) The program grants 7 years of exclusive marketing rights to the manufacturer if
approved.
E) The program accelerates approval of drugs based on preliminary evidence before
formal demonstration of client benefits.
ANSWER: A, C, D
Feedback:
The Orphan Drug Program encourages the development and marketing of products used
to treat rare diseases. The program provides incentives to encourage manufacturers to
develop orphan drugs, and if approved, the manufacturer has 7 years of exclusive
marketing rights. Accelerated programs involve provisional approval and approval
based on preliminary evidence.
,12. After tteaching ta tgroup tof tnursing tstudents tabout tpharmacokinetics, tthe tinstructor
tdetermines tthat tthe tteaching twas tsuccessful twhen tthe tstudents tidentify twhich tof
tthetfollowing tas ta tphase? tSelect tall tthat tapply.
A) Absorption
B) Distribution
C) Administration
D) Metabolism
E) Excretion
tANSWER: tA,
tB, tD,
tEtFeedback:
The tpharmacokinetic tphases tare tabsorption, tdistribution, tmetabolism, tand
texcretion.tThe tacronym tADME tis ta thelpful tway tto tremember tthe tpharmacokinetic
tphases.
13. A tnurse tis tpreparing ta tteaching tplan tfor ta tclient twho tis tprescribed tan toral
tmedication.tAs tpart tof tthe tplan, tthe tnurse texpects tto tdescribe tthe timportance tof
tabsorption. tThe tnurse twould tintegrate tknowledge tof twhich tof tthe tfollowing tas ta
tmechanism tfor tabsorption tin tthe tgastrointestinal ttract? tSelect tall tthat tapply.
A) Active ttransport
B) Transposition
C) Passive ttransport
D) Endocytosis
E) Pinocytosist
ANSWER: t A,
tC, tE tFeedback:
During tabsorption, tthe tdrug tparticles tin tthe tGI ttract tare tmoved tinto tthe tbody tfluids
tviatactive ttransport, tpassive ttransport, tand tpinocytosis.
14. After tteaching ta tgroup tof tnursing tstudents tabout tthe thalf-life tof ta tdrug, tthe
tinstructortdetermines tthe tneed tfor tadditional tteaching twhen tthe tstudents tidentify
twhich tof tthe tfollowing tas ttrue? tSelect tall tthat tapply:
A) Half-life tcan tbe tdecreased tin tclients twith trenal tdisease.
B) Half-life tcan thelp tdetermine tdosing tfrequency.
C) Half-life tdoes tnot tchange tthroughout ta tclient's tlife.
D) Liver tdisease tcan tincrease thalf-life.
E) Half-life tis tthe tmeasure tof tthe trate tat twhich tdrugs tare tremoved tfrom tthe
tbody.tANSWER: t A, tC
Feedback:
Half-life tis tthe tmeasure tof tthe trate tat twhich tdrugs tare tremoved tfrom tthe tbody, tand
tanytdifficulty tin texcreting ta tdrug tincreases thalf-life, tincluding tliver tor tkidney tdisease
tor tadvanced tage.
,15. A tnurse tis tassessing ta tclient tafter tadministering ta tprescribed tmedication. tWhich tof
tthetfollowing twould talert tthe tnurse tto tsuspect tthat tthe tclient tis tdeveloping
tanaphylactic tshock? tSelect tall tthat tapply.
A) Bradycardia
B) Hypertension
C) Dyspnea
D) Urticaria
E) Angioedemat
ANSWER: t C, tD,
tE tFeedback:
The tsymptoms tof tanaphylactic tshock tare tdyspnea, tfeeling tof tfullness tin tthe tthroat,
tcough, twheezing, textremely tlow tblood tpressure, ttachycardia t(heart trate t>100 tbpm),
tpalpitations, tsyncope, tcardiac tarrest, turticaria, tangioedema, tpruritus, tsweating,
tnausea,tvomiting, tand tabdominal tpain.
16. Which tof tthe tfollowing twould tthe tnurse tidentify tas ta tfactor tthat talters tdrug tresponse
tintchildren tand tinfants? tSelect tall tthat tapply.
A) Slower tgastric temptying
B) Greater tsurface tarea
C) Less tprotein tbinding
D) Decreased tbody twater tcontent
E) Less tcutaneous
tfattANSWER: t A, tB, tC,
tE tFeedback:
Children tand tinfants tare tnot tsmall tadults; ttherefore, tthey thave taltered
tpharmacokinetics.tFactors tthat talter tpharmacokinetics tin tchildren tinclude tslower
tgastric temptying, tless tcutaneous tfat, tgreater tsurface tarea, tincreased tbody twater
tcontent, tless tprotein tbinding, tand timmature thepatic tand trenal tfunction.
17. The tFDA testablished ta tsafety tinformation tand tadverse tevents treporting tprogram
tcalled tMedWatch. tWhich tindividuals tcan taccess tthe tMedWatch twebsite tto tobtain
tsafety talertston tdrugs, tdevices, tor tdietary tsupplements? tSelect tall tthat tapply.
A) Physicians
B) Nurses
C) Patients
D) Pharmacists
E) Caregivers
tANSWER: tA, tB,
tC, tD, tEtFeedback:
Anyone tcan taccess tthe tMedWatch twebsite tto tobtain tsafety talerts ton tdrugs, tdevices,
tortdietary tsupplements.
, 18. A tnurse tis tpreparing tto tadminister ta tprescribed tmedication tto ta tclient. tThe tnurse
tintegrates tknowledge tof twhich tof tthe tfollowing tas ta tpossible tfactor tthat tcould
tinfluencetthe tdrug tresponse? tSelect tall tthat tapply.
A) Age
B) Polypharmacy
C) Weight
D) Sex
E) Disease
ANSWER: t A, tB, tC, tD, tE
Feedback:
Drug tresponse tcan tbe tinfluenced tby tthe tfollowing tfactors: tage, tpolypharmacy,
tweight,tsex, tdisease, tand tgenetics.
19. A tnurse tis tassessing ta tclient tand tnotes tthat tthe tclient thas tdeveloped tswelling tof tthe
teyelids tand tlips tafter tadministration tof ta tprescribed tmedication. tThe tnurse tinterprets
tthistfinding tas tspecifically tindicating twhich tof tthe tfollowing?
A) Mild tallergic treaction
B) Anaphylactic tshock
C) Angioedema
D) Drug
tidiosyncrasytANSWER:
tC
Feedback:
Angioedema tis ta ttype tof tallergic tdrug treaction tmanifested tby tthe tcollection tof tfluid tin
tthe tsubcutaneous ttissues, tmost tcommonly taffecting tthe teyelids, tlips, tmouth, tand
tthroat.tAllergic treactions tcan tbe tmanifested tby ta twide trange tof tsigns tand tsymptoms
tsuch tas titching, trashes, tand thives. tAnaphylactic tshock tis ta tserious tallergic treaction
tthat trequirestimmediate tmedical tattention. tDrug tidiosyncrasy tdescribes tany tunusual tor
tabnormal treaction tto ta tdrug, tone tthat tis tdifferent tfrom tthe tone tnormally texpected.
20. Which tof tthe tfollowing tis ttrue tregarding tthe tDietary tSupplement tHealth tand
tEducationtAct t(DSHEA)? tSelect tall tthat tapply.
A) The tact tallows tfor tDEA tenforcement tof tthe tact.
B) The tact tgives tthe tFDA tpower tto tenforce tthe tlaws tgoverned tby tthe tact.
C) The tact tpermits tgeneral thealth tclaims.
D) The tact tpermits tcurative thealth tclaims.
E) The tact tdefines tspecific tsubstances tas t“dietary
tsupplements.”tANSWER: t B, tC, tE
Feedback:
The tDSHEA tdefines tsubstances tsuch tas therbs, tvitamins, tminerals, tamino tacids, tand
tother tnatural tsubstances tas t“dietary tsupplements” tand tpermits tgeneral thealth tclaims
tastlong tas tthe tlabel talso thas ta tdisclaimer tstating tthat tthe tsupplements tare tnot
tapproved tbytthe tFDA tand tare tnot tintended tto tdiagnose, ttreat, tcure, tor tprevent tany
tdisease. tThe tact tgives tthe tFDA tthe tpower tto tenforce tthe tlaws tgoverned tby tthe tact.
