Questions and CORRECT Answers
Which of the following stimulates bile formation and secretion?
a. Cholecystokinin (CCK)
b. Trypsin
c. HCL
d. Gastric lipase
e. Water - CORRECT ANSWER - a. Cholecystokinin (CCK)
Which of the following is NOT a cholesterol transporter?
a. CD36
b. ABCG5/8
c. ABCA1
d. NPC1L1
e. SRB1 - CORRECT ANSWER - a. CD36
Which of the following is NOT a characteristic of HDL?
a. Smallest and most dense lipoprotein particle
b. Involved in reverse cholesterol transport
c. Promotes the formation of fatty plaques in the arteries
d. ApoA1 is only found on HDLs
e. LCAT is required to convert cholesterol into cholesterol-esters - CORRECT ANSWER - c.
Promotes the formation of fatty plaques in the arteries
Chylomicrons and VLDLs contains _________ and __________ that acts as ligands for LDL
receptors, respectively.
a. ApoE, ApoB100
b. ApoE, ApoE
,c. ApoB48, ApoB100
d. ApoCII, ApoB100
e. ApoCII, ApoA1 - CORRECT ANSWER - a. ApoE, ApoB100
Glutamate dehydrogenase converts glutamate to __________.
a. α-ketoglutarate
b. Glutamine
c. Aspartate
d. Acetyl CoA
e. Oxaloacetate - CORRECT ANSWER - a. α-ketoglutarate
Pyridoxal phosphate (PALP) serves as a coenzyme for all the following reactions, EXCEPT?
a. Transamination
b. Decarboxylation of histidine to histamine
c. Heme biosynthesis
d. Deamination
e. Racemization reactions of L-alanine to D-alanine - CORRECT ANSWER - d. deamination
The main form of Vitamin A in animal foods is ____________.
a. B-carotene
b. Retinyl esters
c. All-trans retinoic acid
d. All-trans-retinol
e. Rhodopsin - CORRECT ANSWER - b. Retinyl esters
RXR is a nuclear receptor that can dimerizes with VDR and RAR. The ligand for RXR is
_____________.
a. All-trans RA
,b. 9-cis RA
c. Oxidized LDL
d. 1,25-(OH)2D
e. Cholesterol - CORRECT ANSWER - b. 9-cis RA
CRBP-retinol is esterified to retinyl ester in the enterocytes by the enzyme __________.
a. Retinyl ester hydrolase
b. Lecithin:retinol acyltransferase (LRAT)
c. Retinol dehydrogenase
d. Lecithin:cholesterol acyltransferase (LCAT)
e. Acyl-CoA: cholesterol acyltransferase (ACAT) - CORRECT ANSWER - b. Lecithin:
retinol aycltransfease (LRAT)
High plasma [Ca] stimulates the parathyroid gland to ________ PTH secretion and ________
1,25(OH)2D production.
a. Stimulate, increase
b. Stimulate, decrease
c. Suppress, increase
d. Suppress, no effect
e. Suppress, decrease - CORRECT ANSWER - e. suppress, decrease
Rhodopsin can be formed from _______ only when 11-cis-retinal is present in the photoreceptor
cells.
a. Opsin
b. Light
c. Fatty acid
d. Vitamin D
e. B-carotene - CORRECT ANSWER - a. Opsin
, What is the major site for absorption of macronutrients?
a) Mouth
b) Esophagus
c) Stomach
d) Small Intestine
e) Large Intestine - CORRECT ANSWER - d. small intestine
All of the above are functions of liver EXCEPT:
a) Production of bile
b) Production of urea
c) Detoxification
d) Synthesis of glucose
e) Production of insulin - CORRECT ANSWER - e. production of insulin
Active transport can be characterized by the requirement for which molecule:
a) ATP
b) O2
c) H+
d) H20
e) Creatine phosphate - CORRECT ANSWER - a. ATP
Packaging of lipids into micelles will allow them to travel through __________ during
absorption:
a) Bulk lumen phase
b) Cytoplasm of the enterocyte
c) Unstirred water layer
d) Apical membrane of enterocyte
e) Basolateral membrane of enterocyte - CORRECT ANSWER - c. Unstirred water layer