KATZUNG'S BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION TEST BANK, (2024)
BY TODD W. VANDERAH
ALL CHAPTERS 1-67| 10 SECTIONS| LATEST VERSION WITH ALL DETAILED ANSWERS| GRADE A+
16TH EDITION
,SECTION I: BASIC PRINCIPLES ____________________________________________________ 5
CHAPTER 1: INTRODUCTION: THE NATURE OF DRUGS & DRUG DEVELOPMENT & REGULATION ____________ 5
CHAPTER 2: DRUG RECEPTORS & PHARMACODYNAMICS __________________________________________ 29
CHAPTER 3: PHARMACOKINETICS & PHARMACODYNAMICS: RATIONAL DOSING & THE TIME COURSE OF
DRUG ACTION ______________________________________________________________________________ 54
CHAPTER 4: DRUG BIOTRANSFORMATION ______________________________________________________ 70
CHAPTER 5: PHARMACOGENOMICS ____________________________________________________________ 88
SECTION II: AUTONOMIC DRUGS ________________________________________________ 99
CHAPTER 6. INTRODUCTION TO AUTONOMIC PHARMACOLOGY ____________________________________ 99
CHAPTER 7: CHOLINOCEPTOR-ACTIVATING & CHOLINESTERASE-INHIBITING DRUGS ___________________ 124
CHAPTER 8: CHOLINOCEPTOR-BLOCKING DRUGS ________________________________________________ 146
CHAPTER 9: ADRENOCEPTOR AGONISTS & SYMPATHOMIMETIC DRUGS _____________________________ 169
CHAPTER 10: ADRENOCEPTOR ANTAGONIST DRUGS _____________________________________________ 190
SECTION III: CARDIOVASCULAR-RENAL DRUGS____________________________________ 213
CHAPTER 11: ANTIHYPERTENSIVE AGENTS _____________________________________________________ 213
CHAPTER 12: VASODILATORS & THE TREATMENT OF ANGINA PECTORIS _____________________________ 238
CHAPTER 13: DRUGS USED IN HEART FAILURE __________________________________________________ 259
CHAPTER 14: AGENTS USED IN CARDIAC ARRHYTHMIAS __________________________________________ 280
CHAPTER 15: DIURETIC AGENTS ______________________________________________________________ 303
SECTION IV: DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE _______________ 323
CHAPTER 16: HISTAMINE, SEROTONIN, & THE ERGOT ALKALOIDS __________________________________ 323
CHAPTER 17: VASOACTIVE PEPTIDES __________________________________________________________ 338
CHAPTER 18: THE EICOSANOIDS: PROSTAGLANDINS, THROMBOXANES, LEUKOTRIENES, & RELATED
COMPOUNDS _____________________________________________________________________________ 348
CHAPTER 19: NITRIC OXIDE __________________________________________________________________ 358
CHAPTER 20: DRUGS USED IN ASTHMA & CHRONIC OBSTRUCTIVE PULMONARY DISEASE ______________ 381
SECTION V: DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM ____________________ 399
CHAPTER 21: INTRODUCTION TO THE PHARMACOLOGY OF CNS DRUGS _____________________________ 399
CHAPTER 22: SEDATIVE-HYPNOTIC DRUGS _____________________________________________________ 417
CHAPTER 23: THE ALCOHOLS_________________________________________________________________ 440
CHAPTER 24: ANTISEIZURE DRUGS ____________________________________________________________ 458
CHAPTER 25: GENERAL ANESTHETICS __________________________________________________________ 481
CHAPTER 26: LOCAL ANESTHETICS ____________________________________________________________ 504
CHAPTER 27: SKELETAL MUSCLE RELAXANTS ___________________________________________________ 522
, CHAPTER 28: PHARMACOLOGIC MANAGEMENT OF PARKINSONISM & OTHER MOVEMENT DISORDERS ___ 543
CHAPTER 29: ANTIPSYCHOTIC AGENTS & LITHIUM _______________________________________________ 563
CHAPTER 30: ANTIDEPRESSANT AGENTS _______________________________________________________ 586
CHAPTER 31: OPIOID AGONISTS & ANTAGONISTS _______________________________________________ 611
CHAPTER 32: DRUGS OF ABUSE ______________________________________________________________ 632
SECTION VI: DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT_ 649
CHAPTER 33: AGENTS USED IN CYTOPENIAS; HEMATOPOIETIC GROWTH FACTORS ____________________ 649
CHAPTER 34: DRUGS USED IN DISORDERS OF COAGULATION ______________________________________ 670
CHAPTER 35: AGENTS USED IN DYSLIPIDEMIA __________________________________________________ 690
CHAPTER 36: NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, DISEASE-MODIFYING ANTIRHEUMATIC DRUGS,
NONOPIOID ANALGESICS, & DRUGS USED IN GOUT ______________________________________________ 714
SECTION VII: ENDOCRINE DRUGS ______________________________________________ 736
CHAPTER 37: HYPOTHALAMIC & PITUITARY HORMONES _________________________________________ 736
CHAPTER 38: THYROID & ANTITHYROID DRUGS _________________________________________________ 756
CHAPTER 39: ADRENOCORTICOSTEROIDS & ADRENOCORTICAL ANTAGONISTS _______________________ 779
CHAPTER 40: THE GONADAL HORMONES & INHIBITORS __________________________________________ 802
CHAPTER 41: PANCREATIC HORMONES & GLUCOSE-LOWERING DRUGS _____________________________ 825
CHAPTER 42: AGENTS THAT AFFECT BONE MINERAL HOMEOSTASIS ________________________________ 848
SECTION VIII: CHEMOTHERAPEUTIC DRUGS ______________________________________ 870
CHAPTER 43: BETA-LACTAM & OTHER CELL WALL- & MEMBRANE-ACTIVE ANTIBIOTICS ________________ 870
CHAPTER 44: TETRACYCLINES, MACROLIDES, CLINDAMYCIN, CHLORAMPHENICOL, STREPTOGRAMINS,
OXAZOLIDINONES, & PLEUROMUTILINS _______________________________________________________ 896
CHAPTER 45: AMINOGLYCOSIDES & SPECTINOMYCIN ____________________________________________ 915
CHAPTER 46: SULFONAMIDES, TRIMETHOPRIM, & QUINOLONES ___________________________________ 932
CHAPTER 47: ANTIMYCOBACTERIAL DRUGS ____________________________________________________ 950
CHAPTER 48: ANTIFUNGAL AGENTS ___________________________________________________________ 967
CHAPTER 49: ANTIVIRAL AGENTS _____________________________________________________________ 990
CHAPTER 50: MISCELLANEOUS ANTIMICROBIAL AGENTS; DISINFECTANTS, ANTISEPTICS, & STERILANTS __ 1014
CHAPTER 51: CLINICAL USE OF ANTIMICROBIAL AGENTS _________________________________________ 1040
CHAPTER 52: ANTIPROTOZOAL DRUGS _______________________________________________________ 1059
CHAPTER 53: CLINICAL PHARMACOLOGY OF THE ANTIHELMINTHIC DRUGS _________________________ 1082
CHAPTER 54: CANCER CHEMOTHERAPY _______________________________________________________ 1103
CHAPTER 55: IMMUNOPHARMACOLOGY _____________________________________________________ 1128
SECTION IX: TOXICOLOGY ___________________________________________________ 1153
, CHAPTER 56: INTRODUCTION TO TOXICOLOGY: OCCUPATIONAL & ENVIRONMENTAL_________________ 1153
CHAPTER 57: HEAVY METAL INTOXICATION & CHELATORS _______________________________________ 1195
CHAPTER 58: MANAGEMENT OF THE POISONED PATIENT ________________________________________ 1211
SECTION X: SPECIAL TOPICS __________________________________________________ 1228
CHAPTER 59: SPECIAL ASPECTS OF PERINATAL & PEDIATRIC PHARMACOLOGY _______________________ 1228
CHAPTER 60: SPECIAL ASPECTS OF GERIATRIC PHARMACOLOGY __________________________________ 1239
CHAPTER 61: DERMATOLOGIC PHARMACOLOGY _______________________________________________ 1247
CHAPTER 62: DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISEASES ____________________ 1255
CHAPTER 63: CANNABINOID DRUGS _________________________________________________________ 1276
CHAPTER 64: THERAPEUTIC & TOXIC POTENTIAL OF OVER-THE-COUNTER AGENTS ___________________ 1292
CHAPTER 65; DIETARY SUPPLEMENTS & HERBAL MEDICATIONS ___________________________________ 1316
CHAPTER 66: RATIONAL PRESCRIBING & PRESCRIPTION WRITING _________________________________ 1320
CHAPTER 67: IMPORTANT DRUG INTERACTIONS & THEIR MECHANISMS ____________________________ 1346
16TH EDITION TEST BANK, (2024)
BY TODD W. VANDERAH
ALL CHAPTERS 1-67| 10 SECTIONS| LATEST VERSION WITH ALL DETAILED ANSWERS| GRADE A+
16TH EDITION
,SECTION I: BASIC PRINCIPLES ____________________________________________________ 5
CHAPTER 1: INTRODUCTION: THE NATURE OF DRUGS & DRUG DEVELOPMENT & REGULATION ____________ 5
CHAPTER 2: DRUG RECEPTORS & PHARMACODYNAMICS __________________________________________ 29
CHAPTER 3: PHARMACOKINETICS & PHARMACODYNAMICS: RATIONAL DOSING & THE TIME COURSE OF
DRUG ACTION ______________________________________________________________________________ 54
CHAPTER 4: DRUG BIOTRANSFORMATION ______________________________________________________ 70
CHAPTER 5: PHARMACOGENOMICS ____________________________________________________________ 88
SECTION II: AUTONOMIC DRUGS ________________________________________________ 99
CHAPTER 6. INTRODUCTION TO AUTONOMIC PHARMACOLOGY ____________________________________ 99
CHAPTER 7: CHOLINOCEPTOR-ACTIVATING & CHOLINESTERASE-INHIBITING DRUGS ___________________ 124
CHAPTER 8: CHOLINOCEPTOR-BLOCKING DRUGS ________________________________________________ 146
CHAPTER 9: ADRENOCEPTOR AGONISTS & SYMPATHOMIMETIC DRUGS _____________________________ 169
CHAPTER 10: ADRENOCEPTOR ANTAGONIST DRUGS _____________________________________________ 190
SECTION III: CARDIOVASCULAR-RENAL DRUGS____________________________________ 213
CHAPTER 11: ANTIHYPERTENSIVE AGENTS _____________________________________________________ 213
CHAPTER 12: VASODILATORS & THE TREATMENT OF ANGINA PECTORIS _____________________________ 238
CHAPTER 13: DRUGS USED IN HEART FAILURE __________________________________________________ 259
CHAPTER 14: AGENTS USED IN CARDIAC ARRHYTHMIAS __________________________________________ 280
CHAPTER 15: DIURETIC AGENTS ______________________________________________________________ 303
SECTION IV: DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE _______________ 323
CHAPTER 16: HISTAMINE, SEROTONIN, & THE ERGOT ALKALOIDS __________________________________ 323
CHAPTER 17: VASOACTIVE PEPTIDES __________________________________________________________ 338
CHAPTER 18: THE EICOSANOIDS: PROSTAGLANDINS, THROMBOXANES, LEUKOTRIENES, & RELATED
COMPOUNDS _____________________________________________________________________________ 348
CHAPTER 19: NITRIC OXIDE __________________________________________________________________ 358
CHAPTER 20: DRUGS USED IN ASTHMA & CHRONIC OBSTRUCTIVE PULMONARY DISEASE ______________ 381
SECTION V: DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM ____________________ 399
CHAPTER 21: INTRODUCTION TO THE PHARMACOLOGY OF CNS DRUGS _____________________________ 399
CHAPTER 22: SEDATIVE-HYPNOTIC DRUGS _____________________________________________________ 417
CHAPTER 23: THE ALCOHOLS_________________________________________________________________ 440
CHAPTER 24: ANTISEIZURE DRUGS ____________________________________________________________ 458
CHAPTER 25: GENERAL ANESTHETICS __________________________________________________________ 481
CHAPTER 26: LOCAL ANESTHETICS ____________________________________________________________ 504
CHAPTER 27: SKELETAL MUSCLE RELAXANTS ___________________________________________________ 522
, CHAPTER 28: PHARMACOLOGIC MANAGEMENT OF PARKINSONISM & OTHER MOVEMENT DISORDERS ___ 543
CHAPTER 29: ANTIPSYCHOTIC AGENTS & LITHIUM _______________________________________________ 563
CHAPTER 30: ANTIDEPRESSANT AGENTS _______________________________________________________ 586
CHAPTER 31: OPIOID AGONISTS & ANTAGONISTS _______________________________________________ 611
CHAPTER 32: DRUGS OF ABUSE ______________________________________________________________ 632
SECTION VI: DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT_ 649
CHAPTER 33: AGENTS USED IN CYTOPENIAS; HEMATOPOIETIC GROWTH FACTORS ____________________ 649
CHAPTER 34: DRUGS USED IN DISORDERS OF COAGULATION ______________________________________ 670
CHAPTER 35: AGENTS USED IN DYSLIPIDEMIA __________________________________________________ 690
CHAPTER 36: NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, DISEASE-MODIFYING ANTIRHEUMATIC DRUGS,
NONOPIOID ANALGESICS, & DRUGS USED IN GOUT ______________________________________________ 714
SECTION VII: ENDOCRINE DRUGS ______________________________________________ 736
CHAPTER 37: HYPOTHALAMIC & PITUITARY HORMONES _________________________________________ 736
CHAPTER 38: THYROID & ANTITHYROID DRUGS _________________________________________________ 756
CHAPTER 39: ADRENOCORTICOSTEROIDS & ADRENOCORTICAL ANTAGONISTS _______________________ 779
CHAPTER 40: THE GONADAL HORMONES & INHIBITORS __________________________________________ 802
CHAPTER 41: PANCREATIC HORMONES & GLUCOSE-LOWERING DRUGS _____________________________ 825
CHAPTER 42: AGENTS THAT AFFECT BONE MINERAL HOMEOSTASIS ________________________________ 848
SECTION VIII: CHEMOTHERAPEUTIC DRUGS ______________________________________ 870
CHAPTER 43: BETA-LACTAM & OTHER CELL WALL- & MEMBRANE-ACTIVE ANTIBIOTICS ________________ 870
CHAPTER 44: TETRACYCLINES, MACROLIDES, CLINDAMYCIN, CHLORAMPHENICOL, STREPTOGRAMINS,
OXAZOLIDINONES, & PLEUROMUTILINS _______________________________________________________ 896
CHAPTER 45: AMINOGLYCOSIDES & SPECTINOMYCIN ____________________________________________ 915
CHAPTER 46: SULFONAMIDES, TRIMETHOPRIM, & QUINOLONES ___________________________________ 932
CHAPTER 47: ANTIMYCOBACTERIAL DRUGS ____________________________________________________ 950
CHAPTER 48: ANTIFUNGAL AGENTS ___________________________________________________________ 967
CHAPTER 49: ANTIVIRAL AGENTS _____________________________________________________________ 990
CHAPTER 50: MISCELLANEOUS ANTIMICROBIAL AGENTS; DISINFECTANTS, ANTISEPTICS, & STERILANTS __ 1014
CHAPTER 51: CLINICAL USE OF ANTIMICROBIAL AGENTS _________________________________________ 1040
CHAPTER 52: ANTIPROTOZOAL DRUGS _______________________________________________________ 1059
CHAPTER 53: CLINICAL PHARMACOLOGY OF THE ANTIHELMINTHIC DRUGS _________________________ 1082
CHAPTER 54: CANCER CHEMOTHERAPY _______________________________________________________ 1103
CHAPTER 55: IMMUNOPHARMACOLOGY _____________________________________________________ 1128
SECTION IX: TOXICOLOGY ___________________________________________________ 1153
, CHAPTER 56: INTRODUCTION TO TOXICOLOGY: OCCUPATIONAL & ENVIRONMENTAL_________________ 1153
CHAPTER 57: HEAVY METAL INTOXICATION & CHELATORS _______________________________________ 1195
CHAPTER 58: MANAGEMENT OF THE POISONED PATIENT ________________________________________ 1211
SECTION X: SPECIAL TOPICS __________________________________________________ 1228
CHAPTER 59: SPECIAL ASPECTS OF PERINATAL & PEDIATRIC PHARMACOLOGY _______________________ 1228
CHAPTER 60: SPECIAL ASPECTS OF GERIATRIC PHARMACOLOGY __________________________________ 1239
CHAPTER 61: DERMATOLOGIC PHARMACOLOGY _______________________________________________ 1247
CHAPTER 62: DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISEASES ____________________ 1255
CHAPTER 63: CANNABINOID DRUGS _________________________________________________________ 1276
CHAPTER 64: THERAPEUTIC & TOXIC POTENTIAL OF OVER-THE-COUNTER AGENTS ___________________ 1292
CHAPTER 65; DIETARY SUPPLEMENTS & HERBAL MEDICATIONS ___________________________________ 1316
CHAPTER 66: RATIONAL PRESCRIBING & PRESCRIPTION WRITING _________________________________ 1320
CHAPTER 67: IMPORTANT DRUG INTERACTIONS & THEIR MECHANISMS ____________________________ 1346
