1 Exampromax - Stuvia US 2025/2026
Walden 6630 Psychopharmacology Midterm Study Guide
Questions with Detailed Verified Answers (100% Correct
Answers) /Already Graded A+
Serotonin regulates
Ans: Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them
from reuptake of serotonin to increase levels in the synaptic cleft to bind
with postsysnaptic 5HT2 receptors
Ans: SSRIs
First line therapy for MDD due to milder side effect profiles
Exampromax - Stuvia US
Ans: SSRIs
Approved By:
Six Common SSRIs
Ans: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit from SSRIs
Ans: 4-6 weeks
In addition to MDD, SSRIs also treat
Ans: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include
Ans: Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old
Ans: suicidal ideation
, 2 Exampromax - Stuvia US 2025/2026
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)
Ans: Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the
nervous system
Ans: Serotonin Syndrome
Seven symptoms of Serotonin Syndrome
Ans: Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome
Exampromax - Stuvia US
Ans: Cyproheptadine (5-HT2 receptor antagonist)
Approved By:
Cyproheptadine treats serotonin syndrome by
Ans: blocking 5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include
Ans: Irritability, headaches, and insomnia
Medicine specific side effect of citalopram
Ans: Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart
defects
Ans: Paroxetine
All SSRIs but paroxetine (D) are pregnancy category
Ans: C
, 3 Exampromax - Stuvia US 2025/2026
Three SSRIs that are inhibitors of Cytochrome P450 enzymes
Ans: fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include
Ans: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
This antidepressant class of medications works by binding to presynaptic
SERT and NET to inhibit them from reuptake of serotonin and
norepinephrine to increase their levels in the synaptic cleft
Ans: SNRIs
In addition to MDD SNRIs treat
Exampromax - Stuvia US
Ans: Anxiety and neuropathic pain (peripheral neuropathy)
Approved By:
Medication specific indications of duloxetine:
Ans: urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine:
Ans: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot
flashes
Six common side effects of SNRIs include:
Ans: Insomnia, nausea, sexual dysfunction, hypertension, sweating,
headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old:
Ans: suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in
combination with other serotonergic drugs:
Ans: Serotonin Syndrome
Walden 6630 Psychopharmacology Midterm Study Guide
Questions with Detailed Verified Answers (100% Correct
Answers) /Already Graded A+
Serotonin regulates
Ans: Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them
from reuptake of serotonin to increase levels in the synaptic cleft to bind
with postsysnaptic 5HT2 receptors
Ans: SSRIs
First line therapy for MDD due to milder side effect profiles
Exampromax - Stuvia US
Ans: SSRIs
Approved By:
Six Common SSRIs
Ans: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit from SSRIs
Ans: 4-6 weeks
In addition to MDD, SSRIs also treat
Ans: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include
Ans: Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old
Ans: suicidal ideation
, 2 Exampromax - Stuvia US 2025/2026
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)
Ans: Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the
nervous system
Ans: Serotonin Syndrome
Seven symptoms of Serotonin Syndrome
Ans: Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome
Exampromax - Stuvia US
Ans: Cyproheptadine (5-HT2 receptor antagonist)
Approved By:
Cyproheptadine treats serotonin syndrome by
Ans: blocking 5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include
Ans: Irritability, headaches, and insomnia
Medicine specific side effect of citalopram
Ans: Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart
defects
Ans: Paroxetine
All SSRIs but paroxetine (D) are pregnancy category
Ans: C
, 3 Exampromax - Stuvia US 2025/2026
Three SSRIs that are inhibitors of Cytochrome P450 enzymes
Ans: fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include
Ans: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
This antidepressant class of medications works by binding to presynaptic
SERT and NET to inhibit them from reuptake of serotonin and
norepinephrine to increase their levels in the synaptic cleft
Ans: SNRIs
In addition to MDD SNRIs treat
Exampromax - Stuvia US
Ans: Anxiety and neuropathic pain (peripheral neuropathy)
Approved By:
Medication specific indications of duloxetine:
Ans: urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine:
Ans: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot
flashes
Six common side effects of SNRIs include:
Ans: Insomnia, nausea, sexual dysfunction, hypertension, sweating,
headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old:
Ans: suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in
combination with other serotonergic drugs:
Ans: Serotonin Syndrome
