lOMoAR cPSD| 48898123
Week 6 edapt Endocrene - study for exams
g g g g g g g
AdvancedgPathophysiologyg(ChamberlaingUniversity)
Scan Scangto togopen
opengon
ongStudocuStudocu
Studocu
Studocugis isgnotnotgsponsored
sponsoredgororgendorsed endors
edgby
bygany
anygcollegecollegegororguniversityuniversity
, lOMoAR cPSD| 48898123
ENDOCRENE
Thegpinealgglandgisgresponsiblegforg regulatinggthegsleep-wakegcycle.
Itgmustgbegboundgtogagproteingandgitgbindgtogreceptorsgongthegcellgmembranegrathergthanginsidegth
egcellgmembrane.
Theganteriorglobegofgthegpituitarygproducesgitsgownghormones.
Thegendocrinegcellgcangalsogsecreteghormonesgthatgtargetgcellsgdirectlygclosegit.gWhengthisgoccurs
,gthisgtypegofgsecretiongisgknowngasgparacrinegsignaling.
Thisg statementg isg true.g Lipid-
derivedg hormonesg crossg theg cellg membraneg andgbindg togreceptorsgingthegcell’sgcytoplasm.
Aldosteroneg promotesg sodiumg reabsorptiong andg potassiumg excretiong ing theg kidneys.gTh
eygareglocatedgongthegposteriorglobesgofgthegthyroidggland.
Theg posteriorg pituitaryg receivesg itsg hormonesg (oxytocing andg ADH)g fromg theg hypothalamus.g Thega
nteriorgpituitarygproducesgitsgownghormones.
ADHg isg theg onlyg hormoneg listedg thatg isg producedg byg theg hypothalamus.gT
hegonlygsteroidghormoneglistedgisgtestosterone.
, lOMoAR cPSD| 48898123
Overview of the Endocrine System
g g g g
Theg purposeg ofg theg endocrineg systemg isg tog maintaing theg body’sg homeostasisg usingg hormones.gHo
rmonesg areg signalingg molecules.g Althoughg ag wideg varietyg ofg hormonesg functiong withing thegbody,g
theygsharegcertainggeneralgcharacteristics:
1. Hormonesg haveg speci昀椀
cgratesgandgrhythmsgofgsecretion.gThreegbasicgsecretionggpatternsgare:g (1)g circadiang org diurnal
g patterns,g (2)g pulsatileg andg cyclicg patterns,g andg (3)g patternsgthatg dependg ong levelsg ofg circu
latingg substratesg (e.g.,g calcium,g sodium,g potassium,g org theghormonesgthemselves).
2. Hormonesg operateg withing feedbackg systems,g eitherg positiveg org negative,g tog maintaing ango
ptimalginternalgenvironment.
3. Hormonesg affectg onlyg cellsg withg speci昀椀
cg receptorsg andg theng actg ong thoseg cellsg tog initiategspeci昀椀cgcellgfunctionsgorgactivities.
Whengang endocrinegcellgreceivesgagstimulusgorgcommand,gthisgstimulatesgtheg endocrineg cellgtogse
creteghormonesgintogthegbloodgstream.gTheghormonesgwillgthengtargetgandgbindgontoga
speci昀椀
cg receptorg ong ag targetg cell.g Thisg willg causeg theg targetg cellg tog initiateg ag responseg asg showngingthegdia
gramgbelow:
, lOMoAR cPSD| 48898123
Signaling Hormones
g
Week 6 edapt Endocrene - study for exams
g g g g g g g
AdvancedgPathophysiologyg(ChamberlaingUniversity)
Scan Scangto togopen
opengon
ongStudocuStudocu
Studocu
Studocugis isgnotnotgsponsored
sponsoredgororgendorsed endors
edgby
bygany
anygcollegecollegegororguniversityuniversity
, lOMoAR cPSD| 48898123
ENDOCRENE
Thegpinealgglandgisgresponsiblegforg regulatinggthegsleep-wakegcycle.
Itgmustgbegboundgtogagproteingandgitgbindgtogreceptorsgongthegcellgmembranegrathergthanginsidegth
egcellgmembrane.
Theganteriorglobegofgthegpituitarygproducesgitsgownghormones.
Thegendocrinegcellgcangalsogsecreteghormonesgthatgtargetgcellsgdirectlygclosegit.gWhengthisgoccurs
,gthisgtypegofgsecretiongisgknowngasgparacrinegsignaling.
Thisg statementg isg true.g Lipid-
derivedg hormonesg crossg theg cellg membraneg andgbindg togreceptorsgingthegcell’sgcytoplasm.
Aldosteroneg promotesg sodiumg reabsorptiong andg potassiumg excretiong ing theg kidneys.gTh
eygareglocatedgongthegposteriorglobesgofgthegthyroidggland.
Theg posteriorg pituitaryg receivesg itsg hormonesg (oxytocing andg ADH)g fromg theg hypothalamus.g Thega
nteriorgpituitarygproducesgitsgownghormones.
ADHg isg theg onlyg hormoneg listedg thatg isg producedg byg theg hypothalamus.gT
hegonlygsteroidghormoneglistedgisgtestosterone.
, lOMoAR cPSD| 48898123
Overview of the Endocrine System
g g g g
Theg purposeg ofg theg endocrineg systemg isg tog maintaing theg body’sg homeostasisg usingg hormones.gHo
rmonesg areg signalingg molecules.g Althoughg ag wideg varietyg ofg hormonesg functiong withing thegbody,g
theygsharegcertainggeneralgcharacteristics:
1. Hormonesg haveg speci昀椀
cgratesgandgrhythmsgofgsecretion.gThreegbasicgsecretionggpatternsgare:g (1)g circadiang org diurnal
g patterns,g (2)g pulsatileg andg cyclicg patterns,g andg (3)g patternsgthatg dependg ong levelsg ofg circu
latingg substratesg (e.g.,g calcium,g sodium,g potassium,g org theghormonesgthemselves).
2. Hormonesg operateg withing feedbackg systems,g eitherg positiveg org negative,g tog maintaing ango
ptimalginternalgenvironment.
3. Hormonesg affectg onlyg cellsg withg speci昀椀
cg receptorsg andg theng actg ong thoseg cellsg tog initiategspeci昀椀cgcellgfunctionsgorgactivities.
Whengang endocrinegcellgreceivesgagstimulusgorgcommand,gthisgstimulatesgtheg endocrineg cellgtogse
creteghormonesgintogthegbloodgstream.gTheghormonesgwillgthengtargetgandgbindgontoga
speci昀椀
cg receptorg ong ag targetg cell.g Thisg willg causeg theg targetg cellg tog initiateg ag responseg asg showngingthegdia
gramgbelow:
, lOMoAR cPSD| 48898123
Signaling Hormones
g
