TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
TEST BANK FOR GENETICS FROM G
g g g g g
ENES TO GENOMES 6TH EDITION B
g g g g g
Y HARTWELL
g
Genetics From Genes To Genomes 6th Edition H
g g g g g g g
artwell Test Bank g g
Hartwell
Chapterg1g Genetics:gThegStudygofgBiologicalgInformation
1) HowgdoesgDNAgstructuregrelategtogitsgfunction?
- ThegordergofgnucleotidesgingagDNAgstrandgspecifiesgthegordergofgaminogacidsg
ingaIprotein.
2) WhatgisgagdifferencegbetweengthegstructuregofgDNAgandgproteins?
- DNAgisgcomposedgofgnucleotidesgandgproteinsgaregcomposedgofgaminogacids.
3) Aggenomegcangbegbestgdescribedgas
- thegDNAgingallgchromosomesgingagcell.
4) WhatgisgthegdifferencegbetweengthegfunctiongofgDNAgandgthegfunctiongofgproteins?
- DNAgstoresggeneticginformationgandgproteinsgperformgmostgcellulargfunctions.
5) Whichgstatementgsupportsgthegtheorygthatgallgorganismsgaregrelated?
- Theggeneticgcodegisgalmostguniversal.
6) Newggenesgaregthoughtgtogarisegbygwhichgmechanism?
- Genegduplicationgfollowedgbygdivergencegduegtogmutation.
7) Whatgisgthegmostglikelygwaygagmutationgingoneggenegcangconvertgonegbodygpartgto
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
,TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
another?
- Thegmutatedggenegencodesgagproteingthatgaffectsgthegexpressiongofgmanygother
genes.
8) Agrecentgtechnicalgadvancementgthatghasgacceleratedgthegstudygofggenomesgisgt
hegabilityto
- sequenceglargegcomplexggenomesgrapidlygandginexpensively.
9) Whatgisgthegdifferencegbetweenggeneticgdissectiongandggenomegsequencing?
- Geneticgdissectiongrevealsginformationgaboutgoneggenegatgagtimegandgg
enomesequencinggrevealsginformationgaboutgallgtheggenesgingaggenomegatgonce
.
10) Currently,gwhatginformationgcangbegobtainedgfromgsequencinggangindividual'sggenome?
- Informationgaboutggenegvariantsgthatgpredisposegagpersongtogagdisease,gsuc
hgasIcancer.
11) Whichgisgnotgagpotentialgproblemgofgallowinggtheggenomicgsequencesgofgindividua
lsgtobecomegwidelygavailable?
- Advancesgleadinggtoghealthierglivesgforgsomegpeople.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
,TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
12) OnegstrandgofgDNAghasgthegsequenceg5′gGGTCTAg3′.gWhatgisgthegsequencegofgthegot
herstrand?
- 5′gTAGACCg3′
13) WhichgstatementgisgtruegaboutgthegstructuregofgDNA?
- ThegtwogstrandsgofgagDNAgmoleculegaregheldgtogethergbygbasegpairing.
14) Thegsizegofgthegmouseg(M.gmusculus)ggenomegisg2700gmegabasesg(Mb)g andg itg cont
ainsgaboutg25,000ggenesgarrangedgong40gchromosomes.gIfgtheggenesgaregevenlygdistrib
utedgongchromosomesgingthegmouse,gwhatgisgthegaveragegnumbergofggenesgpergchromos
ome?
-g625
15) Whichgstatementgaboutgthegstructuregofgproteinsgisgfalse?
- Mostgproteinsgconsistgofgtwogaminogacidgpolymersgattachedgtogethergbyghydroge
ngbonding.
16) WhichgisgagstructuralgfeaturegsharedgbygDNA,gRNA,gandgproteins?
- Thegordergofgmonomersgisgimportantgforgfunction.
17) AgsegmentgofgagproteinghasgthegaminogacidgsequencegSer—Gly—
Leu.gIsgitgpossiblegtoinfergthegsequencegofgthegRNAgthatgencodesgthisgaminogacidgsequ
ence?
No;gmoregthangonegtypegofgRNAg(moregthangonegbasegsequence)gcouldgencodegthisgamino
acidgsequence.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
, TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
18) AgsequencegofgbasesgingthegmiddlegofgangRNAgusedgtogencodegagpolypeptideghasgthegs
equencegUUA—AUG—
CGU.gIsgitgpossiblegtoginfergthegsequencegofgthegaminogacidsgencodedgbygthisgRNA?
- Yes,gthegsequencegisgLeu—Met—Arg.
19) Mutationgofgagmouseggenegresultsgingmicegthatglackgheartgmuscle.gWhatgcharacterist
icgwouldgyougexpectgtogfindgingaghumanggenegthatghasgagcommongorigingwithgthisgmous
eggene?
- Theghumangandgmouseggenesgwillgspecifygproteinsgwithgsimilargamin
ogacidsequences.
20) Agmouseggenegwasgidentifiedgandgdeterminedgtogbegrequiredgforgformationgofghea
rtgmuscle.gAggenegwithgagsimilargsequencegwasgidentifiedgingtheghumanggenome.gWha
tgexperimentgcouldgscientistsgdogtogdeterminegifgthegmousegandghumanggenesghavegsi
milarfunctions?
- Thegscientistgcouldgplacegthegnormalghumanggenegintogmutantgmicegtogsee
gifgheartmusclegformsgingthegmouse.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
ELL
TEST BANK FOR GENETICS FROM G
g g g g g
ENES TO GENOMES 6TH EDITION B
g g g g g
Y HARTWELL
g
Genetics From Genes To Genomes 6th Edition H
g g g g g g g
artwell Test Bank g g
Hartwell
Chapterg1g Genetics:gThegStudygofgBiologicalgInformation
1) HowgdoesgDNAgstructuregrelategtogitsgfunction?
- ThegordergofgnucleotidesgingagDNAgstrandgspecifiesgthegordergofgaminogacidsg
ingaIprotein.
2) WhatgisgagdifferencegbetweengthegstructuregofgDNAgandgproteins?
- DNAgisgcomposedgofgnucleotidesgandgproteinsgaregcomposedgofgaminogacids.
3) Aggenomegcangbegbestgdescribedgas
- thegDNAgingallgchromosomesgingagcell.
4) WhatgisgthegdifferencegbetweengthegfunctiongofgDNAgandgthegfunctiongofgproteins?
- DNAgstoresggeneticginformationgandgproteinsgperformgmostgcellulargfunctions.
5) Whichgstatementgsupportsgthegtheorygthatgallgorganismsgaregrelated?
- Theggeneticgcodegisgalmostguniversal.
6) Newggenesgaregthoughtgtogarisegbygwhichgmechanism?
- Genegduplicationgfollowedgbygdivergencegduegtogmutation.
7) Whatgisgthegmostglikelygwaygagmutationgingoneggenegcangconvertgonegbodygpartgto
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
,TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
another?
- Thegmutatedggenegencodesgagproteingthatgaffectsgthegexpressiongofgmanygother
genes.
8) Agrecentgtechnicalgadvancementgthatghasgacceleratedgthegstudygofggenomesgisgt
hegabilityto
- sequenceglargegcomplexggenomesgrapidlygandginexpensively.
9) Whatgisgthegdifferencegbetweenggeneticgdissectiongandggenomegsequencing?
- Geneticgdissectiongrevealsginformationgaboutgoneggenegatgagtimegandgg
enomesequencinggrevealsginformationgaboutgallgtheggenesgingaggenomegatgonce
.
10) Currently,gwhatginformationgcangbegobtainedgfromgsequencinggangindividual'sggenome?
- Informationgaboutggenegvariantsgthatgpredisposegagpersongtogagdisease,gsuc
hgasIcancer.
11) Whichgisgnotgagpotentialgproblemgofgallowinggtheggenomicgsequencesgofgindividua
lsgtobecomegwidelygavailable?
- Advancesgleadinggtoghealthierglivesgforgsomegpeople.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
,TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
12) OnegstrandgofgDNAghasgthegsequenceg5′gGGTCTAg3′.gWhatgisgthegsequencegofgthegot
herstrand?
- 5′gTAGACCg3′
13) WhichgstatementgisgtruegaboutgthegstructuregofgDNA?
- ThegtwogstrandsgofgagDNAgmoleculegaregheldgtogethergbygbasegpairing.
14) Thegsizegofgthegmouseg(M.gmusculus)ggenomegisg2700gmegabasesg(Mb)g andg itg cont
ainsgaboutg25,000ggenesgarrangedgong40gchromosomes.gIfgtheggenesgaregevenlygdistrib
utedgongchromosomesgingthegmouse,gwhatgisgthegaveragegnumbergofggenesgpergchromos
ome?
-g625
15) Whichgstatementgaboutgthegstructuregofgproteinsgisgfalse?
- Mostgproteinsgconsistgofgtwogaminogacidgpolymersgattachedgtogethergbyghydroge
ngbonding.
16) WhichgisgagstructuralgfeaturegsharedgbygDNA,gRNA,gandgproteins?
- Thegordergofgmonomersgisgimportantgforgfunction.
17) AgsegmentgofgagproteinghasgthegaminogacidgsequencegSer—Gly—
Leu.gIsgitgpossiblegtoinfergthegsequencegofgthegRNAgthatgencodesgthisgaminogacidgsequ
ence?
No;gmoregthangonegtypegofgRNAg(moregthangonegbasegsequence)gcouldgencodegthisgamino
acidgsequence.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
, TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
18) AgsequencegofgbasesgingthegmiddlegofgangRNAgusedgtogencodegagpolypeptideghasgthegs
equencegUUA—AUG—
CGU.gIsgitgpossiblegtoginfergthegsequencegofgthegaminogacidsgencodedgbygthisgRNA?
- Yes,gthegsequencegisgLeu—Met—Arg.
19) Mutationgofgagmouseggenegresultsgingmicegthatglackgheartgmuscle.gWhatgcharacterist
icgwouldgyougexpectgtogfindgingaghumanggenegthatghasgagcommongorigingwithgthisgmous
eggene?
- Theghumangandgmouseggenesgwillgspecifygproteinsgwithgsimilargamin
ogacidsequences.
20) Agmouseggenegwasgidentifiedgandgdeterminedgtogbegrequiredgforgformationgofghea
rtgmuscle.gAggenegwithgagsimilargsequencegwasgidentifiedgingtheghumanggenome.gWha
tgexperimentgcouldgscientistsgdogtogdeterminegifgthegmousegandghumanggenesghavegsi
milarfunctions?
- Thegscientistgcouldgplacegthegnormalghumanggenegintogmutantgmicegtogsee
gifgheartmusclegformsgingthegmouse.
TESTgBANKgFORgGENETICSgFROMgGENESgTOgGENOMESg6THgEDITIONgBYgHARTW
ELL
