3/16/25, 3:47 PM NR 565 Midterm Flashcards | Quizlet
NR 565 Midterm
NURS 565 MIDTERM TEST BANK NEWEST 2025 ACTUAL EXAM
COMPLETEQUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+||BRAND NEW
VERSION!!
Promote drug excretion by making them more
"excretable"--hydrophilic/water soluble and charged
What do CYP450 enzymes (ion)
do? Inactivate drugs, increase therapeutic action through
metabolism, activate a prodrug, decrease drug toxicity
VISA credit card debt inhibits spending on designers like
CK to look GQ Valproate
Isoniazid Sulfonamides Amiodarone Chloramphenicol
Ketoconzaole Grapefruit juice Quinidine
CYP450 inhibitor
examples?
Therapeutic response of Starting early can delay joint degradation
MTX?
MTX, leflunomide, sulfasalazine, hydroxychloroquine
Conventional DMARDs Inhibits dihydroflorate reductase,
inhibits lymphocyte proliferation
Monitor LFTs, creatinine
Adalimumab (Humira), certolizumab pegol, etanerdept,
Biologic DMARDs golimumab
Binds and inhibits tumor necrosis factor-alpha,
reducing inflammation and altering immune
response
Tofacitinib, barcitinib
Targeted DMARDs Inhibits JAK 1,2,3, leading to disruption of
cytokine and growth factor signaling
1/2
1
,3/16/25, 3:47 PM NR 565 Midterm Flashcards | Quizlet
pathways
Alendronate Biphosphonate, used as first-line
treatment for osteoporosis
Inhibits osteoclasts, reducing
bone resorption and turnover
Which dietary Antacids, calcium, iron and magnesium
supplements interfere
with absorption of
biphosphonates?
Swallow tablet with a full glass of water on an
Patient education for empty stomach while sitting or standing
biphosphonates? Remain upright for 30-60 minutes
Typical daily dose of 5-10mg PO daily
lisinopril?
Typical daily dose of 5 mg PO daily to start, maintenance 5-10mg PO daily
amlodipine?
Typical daily dose of 1.2-2.4 mg PO daily divided in 1 or 2 doses
colchicine?
5/325 1-2 tab Q4-6 hrs (12 tab daily)
Typical daily dose of 7.5/325 1 tab Q4-6 hrs
Lortab? (6 tabs daily) 10/325 1
tab Q4-6 hrs (6 tabs
daily)
Which Varies state by state
schedule drugs May include schedule II-V, but never schedule I
can APRNs
prescribe?
Who determines The state's health professional board
and regulates
prescriptive
authority?
How does limited Creates numerous barriers to quality, affordable, and accessible
patient care May prevent outreach to areas of greatest need
2/2
1
, 3/16/25, 3:47 PM NR 565 Midterm Flashcards | Quizlet
prescriptive Physician approval of prescriptions can increase patient waits
authority
impact
patients within
the healthcare
system?
A sound understanding of drugs and the conditions that they are
used to manage Be deliberate in decision-making process
Do not prescribe for family or friends
What are the key Document thorough history and physical for the records, including
responsibilities education provided on drug
of prescribing? Have a documented plan for monitoring and titration
What should be Cost, follow current guidelines, availability, interactions, side
used in effects, allergies, hepatic/renal function, need for monitoring,
special populations
making
prescribing
decisions?
PK and PD Very high risk of adverse drug reactions and drug-drug
changes in interactions
D/t altered PK, multiple and severe illnesses, polypharmacy, poor
older adults
adherence
and how that
affects how
you prescribe?
List of potentially inappropriate medications to use in the older
populations Updated annually
Beer's Criteria
Prescribers ultimately decide whether to prescribe or not
Impacts/outcome Increased ADRs and drug-drug interactions
s of
polypharmacy?
Enzymes responsible for drug metabolism (biotransformation)-
oxidization, reduction, hydrolyzed to promote renal dug excretion
What are
Hepatic enzyme system, composed of 12 enzyme families
CYP450?
3/2
1
NR 565 Midterm
NURS 565 MIDTERM TEST BANK NEWEST 2025 ACTUAL EXAM
COMPLETEQUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+||BRAND NEW
VERSION!!
Promote drug excretion by making them more
"excretable"--hydrophilic/water soluble and charged
What do CYP450 enzymes (ion)
do? Inactivate drugs, increase therapeutic action through
metabolism, activate a prodrug, decrease drug toxicity
VISA credit card debt inhibits spending on designers like
CK to look GQ Valproate
Isoniazid Sulfonamides Amiodarone Chloramphenicol
Ketoconzaole Grapefruit juice Quinidine
CYP450 inhibitor
examples?
Therapeutic response of Starting early can delay joint degradation
MTX?
MTX, leflunomide, sulfasalazine, hydroxychloroquine
Conventional DMARDs Inhibits dihydroflorate reductase,
inhibits lymphocyte proliferation
Monitor LFTs, creatinine
Adalimumab (Humira), certolizumab pegol, etanerdept,
Biologic DMARDs golimumab
Binds and inhibits tumor necrosis factor-alpha,
reducing inflammation and altering immune
response
Tofacitinib, barcitinib
Targeted DMARDs Inhibits JAK 1,2,3, leading to disruption of
cytokine and growth factor signaling
1/2
1
,3/16/25, 3:47 PM NR 565 Midterm Flashcards | Quizlet
pathways
Alendronate Biphosphonate, used as first-line
treatment for osteoporosis
Inhibits osteoclasts, reducing
bone resorption and turnover
Which dietary Antacids, calcium, iron and magnesium
supplements interfere
with absorption of
biphosphonates?
Swallow tablet with a full glass of water on an
Patient education for empty stomach while sitting or standing
biphosphonates? Remain upright for 30-60 minutes
Typical daily dose of 5-10mg PO daily
lisinopril?
Typical daily dose of 5 mg PO daily to start, maintenance 5-10mg PO daily
amlodipine?
Typical daily dose of 1.2-2.4 mg PO daily divided in 1 or 2 doses
colchicine?
5/325 1-2 tab Q4-6 hrs (12 tab daily)
Typical daily dose of 7.5/325 1 tab Q4-6 hrs
Lortab? (6 tabs daily) 10/325 1
tab Q4-6 hrs (6 tabs
daily)
Which Varies state by state
schedule drugs May include schedule II-V, but never schedule I
can APRNs
prescribe?
Who determines The state's health professional board
and regulates
prescriptive
authority?
How does limited Creates numerous barriers to quality, affordable, and accessible
patient care May prevent outreach to areas of greatest need
2/2
1
, 3/16/25, 3:47 PM NR 565 Midterm Flashcards | Quizlet
prescriptive Physician approval of prescriptions can increase patient waits
authority
impact
patients within
the healthcare
system?
A sound understanding of drugs and the conditions that they are
used to manage Be deliberate in decision-making process
Do not prescribe for family or friends
What are the key Document thorough history and physical for the records, including
responsibilities education provided on drug
of prescribing? Have a documented plan for monitoring and titration
What should be Cost, follow current guidelines, availability, interactions, side
used in effects, allergies, hepatic/renal function, need for monitoring,
special populations
making
prescribing
decisions?
PK and PD Very high risk of adverse drug reactions and drug-drug
changes in interactions
D/t altered PK, multiple and severe illnesses, polypharmacy, poor
older adults
adherence
and how that
affects how
you prescribe?
List of potentially inappropriate medications to use in the older
populations Updated annually
Beer's Criteria
Prescribers ultimately decide whether to prescribe or not
Impacts/outcome Increased ADRs and drug-drug interactions
s of
polypharmacy?
Enzymes responsible for drug metabolism (biotransformation)-
oxidization, reduction, hydrolyzed to promote renal dug excretion
What are
Hepatic enzyme system, composed of 12 enzyme families
CYP450?
3/2
1
