MARYVILLE NURS 615 PHARM RELIABLE EXAM QUESTION
WITH ANSWERS 2025/2026
What is the MOA for benzodiazapine? - binds to GABA receptors to inhibit the
neurotransmitter release;
↑ action of GABA, ↓ neuronal excitment (CNS depression)
What can occur if Benzo use is combined with ETOH or other CNS depressants? -
Sedative effects
How should benzos be discontinued? - wean off; potential for withdrawal sx
What is the MOA with Buspirone (Buspar)? - full agonist for presynaptic, partial agonist
for postsynaptic; if too much serotonin=antagonist; if too little serotonin=agonist
What receptors do the antidepressants and antianxiety medications act on - SSRI (↑
Serotonin), SNRI & TCA (↑ serotonin/Norepi), MAOI ( ↑ serotonin/Norepi/dopamine),
Anxiolytic; Benzos ( (↑ GABA, ↓ neuronal excitation: ↑ FREQ of opening CL-
channel=CNS depression)
What class is zolidem (Ambien) and what is the MOA? - nonbenzodiazepine hypnotic;
acts at the GABA receptor but not benzo site
What class is temazapam and the MOA? - Benzodiazepine that treats insomnia; (↑
GABA, ↓ neuronal excitation).
What does healthy sleep hygiene refer too? - interventions that increase the quality of
sleep
how should insomnia med be prescribed? - only for short period of time while pt
develops good sleep habits and patterns
What factors will place the patient at risk for antibiotic resistance? - bacteria genetic
mutation, elder, infants, pt noncompliance, immunocompromised
What factors place the patient at risk for hypersensitivity reactions with penicillins and
cephalosporins? - there is a cross sensitivity reaction due to the fact that each class
contains a bata lactam ring
What are the safest antibiotics to prescribe to a woman who is pregnant and which ones
should be avoided? - Penicillins, & cephlasporins; avoid tetracycline & quinolones
what factors can cause/exacerbate resistance to antibiotics? - Inactivation of drug (beta-
lactamase), altered target (change binding sites), reduced influx, and Increased efflux
, Which antibiotics inhibit bacterial cell wall synthesis? - bactericidal; beta-lactams;
penicillin, cephalosporin, carbapenems, monbactams
Why is clavulanate added to Amoxicillin? - it is a beta-lactamase inhibitory; gram-neg
have ↑ B-L so enhances antibx ability to attack
What antibiotics are appropriate to prescribe to children? - Penicillins, cephalosporin,
erythromycin
Which antibiotics block bacterial protein production? - bacteriostatic; Macrolides
(erythromycin), Tetracyclines, Lincosamides (Clindamycin), Rifampin,
Ototoxicity and nephrotoxicity associated with this antibiotic: - Aminoglycosides;GNATS
gentamicin, neomycin, amikacin, tobramycin, streptomycin
Alternative antimicrobial drug(s) for treating penicillin-resistant S. aureus: - vancomycin
& methacillin
Antibiotics That Target the Cell Wall - Gram-Pos;beta-lactams; penicillin, cephalosporin,
carbapenem, monobactams, bacitracin, vancomycin; Gram Neg; polymyxin
Antibiotics That Block Protein Production - •Chloramphenicol
•Macrolides
•Oxazolidinone
•Mupirocin
•Clindamycin
•Aminoglycoside
•Rifampin
•Tetracycline
•Streptogramin (C MOM CARTS)
Antibiotics That Target DNA and Replication - Sulfonamides, Trimethoprim, Quinolones,
Metronidazole
What is bacteriostatic? - inhibits reproduction of bacteria
What is bactericidal? - kills bacteria
What patient teaching will you provide to a patient who is experiencing non-infectious
diarrhea related to antibiotic administration - need to be assessed for C-diff; increase
probiotic to repopulate gut flora
What affects antibiotic efficacy? - Immunocompromised & Presence of foreign body
(medical devices), distribution (must reach site)
WITH ANSWERS 2025/2026
What is the MOA for benzodiazapine? - binds to GABA receptors to inhibit the
neurotransmitter release;
↑ action of GABA, ↓ neuronal excitment (CNS depression)
What can occur if Benzo use is combined with ETOH or other CNS depressants? -
Sedative effects
How should benzos be discontinued? - wean off; potential for withdrawal sx
What is the MOA with Buspirone (Buspar)? - full agonist for presynaptic, partial agonist
for postsynaptic; if too much serotonin=antagonist; if too little serotonin=agonist
What receptors do the antidepressants and antianxiety medications act on - SSRI (↑
Serotonin), SNRI & TCA (↑ serotonin/Norepi), MAOI ( ↑ serotonin/Norepi/dopamine),
Anxiolytic; Benzos ( (↑ GABA, ↓ neuronal excitation: ↑ FREQ of opening CL-
channel=CNS depression)
What class is zolidem (Ambien) and what is the MOA? - nonbenzodiazepine hypnotic;
acts at the GABA receptor but not benzo site
What class is temazapam and the MOA? - Benzodiazepine that treats insomnia; (↑
GABA, ↓ neuronal excitation).
What does healthy sleep hygiene refer too? - interventions that increase the quality of
sleep
how should insomnia med be prescribed? - only for short period of time while pt
develops good sleep habits and patterns
What factors will place the patient at risk for antibiotic resistance? - bacteria genetic
mutation, elder, infants, pt noncompliance, immunocompromised
What factors place the patient at risk for hypersensitivity reactions with penicillins and
cephalosporins? - there is a cross sensitivity reaction due to the fact that each class
contains a bata lactam ring
What are the safest antibiotics to prescribe to a woman who is pregnant and which ones
should be avoided? - Penicillins, & cephlasporins; avoid tetracycline & quinolones
what factors can cause/exacerbate resistance to antibiotics? - Inactivation of drug (beta-
lactamase), altered target (change binding sites), reduced influx, and Increased efflux
, Which antibiotics inhibit bacterial cell wall synthesis? - bactericidal; beta-lactams;
penicillin, cephalosporin, carbapenems, monbactams
Why is clavulanate added to Amoxicillin? - it is a beta-lactamase inhibitory; gram-neg
have ↑ B-L so enhances antibx ability to attack
What antibiotics are appropriate to prescribe to children? - Penicillins, cephalosporin,
erythromycin
Which antibiotics block bacterial protein production? - bacteriostatic; Macrolides
(erythromycin), Tetracyclines, Lincosamides (Clindamycin), Rifampin,
Ototoxicity and nephrotoxicity associated with this antibiotic: - Aminoglycosides;GNATS
gentamicin, neomycin, amikacin, tobramycin, streptomycin
Alternative antimicrobial drug(s) for treating penicillin-resistant S. aureus: - vancomycin
& methacillin
Antibiotics That Target the Cell Wall - Gram-Pos;beta-lactams; penicillin, cephalosporin,
carbapenem, monobactams, bacitracin, vancomycin; Gram Neg; polymyxin
Antibiotics That Block Protein Production - •Chloramphenicol
•Macrolides
•Oxazolidinone
•Mupirocin
•Clindamycin
•Aminoglycoside
•Rifampin
•Tetracycline
•Streptogramin (C MOM CARTS)
Antibiotics That Target DNA and Replication - Sulfonamides, Trimethoprim, Quinolones,
Metronidazole
What is bacteriostatic? - inhibits reproduction of bacteria
What is bactericidal? - kills bacteria
What patient teaching will you provide to a patient who is experiencing non-infectious
diarrhea related to antibiotic administration - need to be assessed for C-diff; increase
probiotic to repopulate gut flora
What affects antibiotic efficacy? - Immunocompromised & Presence of foreign body
(medical devices), distribution (must reach site)
