MICROBIOLOGY 212
CHAPTER 12 EXAM 2
[Document subtitle]
[DATE]
[COMPANY NAME]
[Company address]
, . What are Tetracycline Antibiotics?
Answer: Broad-spectrum antibiotics that block protein synthesis by binding ribosomes;
used to treat mycoplasmas, rickettsia, and spirochetes; easy on the stomach; cannot
be taken by pregnant women or children due to effects on teeth.
2. What do synthesized quinolines such as chloroquine and primaquine do?
Answer: They are less toxic and replaced Quinine.
3. What are Probiotics?
Answer: Probiotics replace normal flora in the body.
4. What is the therapeutic index?
Answer: The ratio of the dose of drug that is toxic to humans to its minimum effective
dose (the smaller the ratio, the higher the chances of toxicity).
5. What does Trimethoprim do?
Answer: It blocks folic acid synthesis further down the pathway; used to treat
pneumocystis commonly found in AIDS patients.
6. What are Aminoglycosides?
Answer: They target protein synthesis, derived from species of soil actinomycetes in the
genera Streptomyces and Micromonospora; subgroups include streptomycin,
gentamicin, and neomycin.
7. What is Flucytosine?
Answer: It inhibits nucleic acid by mimicking cytosine; it is narrow spectrum and very
toxic, used to treat cutaneous mycoses.
8. What are Sulfones?
Answer: They work by interfering with mycolic acid synthesis and are used to treat
infections with Mycobacterium tuberculosis; they are similar to sulfonamides but not as
broad spectrum and used to treat leprosy.
CHAPTER 12 EXAM 2
[Document subtitle]
[DATE]
[COMPANY NAME]
[Company address]
, . What are Tetracycline Antibiotics?
Answer: Broad-spectrum antibiotics that block protein synthesis by binding ribosomes;
used to treat mycoplasmas, rickettsia, and spirochetes; easy on the stomach; cannot
be taken by pregnant women or children due to effects on teeth.
2. What do synthesized quinolines such as chloroquine and primaquine do?
Answer: They are less toxic and replaced Quinine.
3. What are Probiotics?
Answer: Probiotics replace normal flora in the body.
4. What is the therapeutic index?
Answer: The ratio of the dose of drug that is toxic to humans to its minimum effective
dose (the smaller the ratio, the higher the chances of toxicity).
5. What does Trimethoprim do?
Answer: It blocks folic acid synthesis further down the pathway; used to treat
pneumocystis commonly found in AIDS patients.
6. What are Aminoglycosides?
Answer: They target protein synthesis, derived from species of soil actinomycetes in the
genera Streptomyces and Micromonospora; subgroups include streptomycin,
gentamicin, and neomycin.
7. What is Flucytosine?
Answer: It inhibits nucleic acid by mimicking cytosine; it is narrow spectrum and very
toxic, used to treat cutaneous mycoses.
8. What are Sulfones?
Answer: They work by interfering with mycolic acid synthesis and are used to treat
infections with Mycobacterium tuberculosis; they are similar to sulfonamides but not as
broad spectrum and used to treat leprosy.
