NURS 5334 Antimicrobials
NURS 5334 Part
Antimicrobials
NURS
1_ Cell
5334
Wall
Part
Antimicrobials
Inhibitors,
1_ Cell Wall
Beta-Lactam
Part
Inhibitors,
1_ CellAntibiotics
Wall
Beta-Lactam
Inhibitors,
& Beta-Lactamase
Antibiotics
Beta-Lactam
& Beta-Lactamase
Inhibitors
AntibioticsStudy
& Beta-Lactamase
Inhibitors
Guide.pdfStudyInhibitors
Guide.pdfStudy Guide.pdf
NURS 5334 Antimicrobials Part 1: Cell
Wall Inhibitors, Beta-Lactam Antibiotics
& Beta-Lactamase Inhibitors Study
Guide
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_
NURS 5334 Antimicrobials
NURS 5334 Part
Antimicrobials
NURS
1_ Cell
5334
Wall
Part
Antimicrobials
Inhibitors,
1_ Cell Wall
Beta-Lactam
Part
Inhibitors,
1_ CellAntibiotics
Wall
Beta-Lactam
Inhibitors,
& Beta-Lactamase
Antibiotics
Beta-Lactam
& Beta-Lactamase
Inhibitors
AntibioticsStudy
& Beta-Lactamase
Inhibitors
Guide.pdfStudyInhibitors
Guide.pdfStudy Guide.pdf
,Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
1 MRSA 2 HIV
3 MSSA 4 VRE
Don't know?
Terms in this set (100)
How do antimicrobials work? ABX: kill pathogens without harming the cell or host
ABX selection requires what identity and susceptibility of pathogen
site of infection
patient factors
safey and efficacy of agent
cost
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
,Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
Empiric Therapy TXT provided prior to bacteria ID
Usualy in acute patients with neutropenia, meningitis, etc
Bacteriostatic inhibits bacterial growth
Bacteriocidal kills bacteria
it is possible for a drug to be both bacteriostatic for one microbe and
bacterocidal for another
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
, Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
Minimum inhibitory concentration (MIC) lowest abx concentration that stops visible bacteria growth after 24 hrs of
incubation
Affects the efficacy of drug
Minimum bactericidal concentration (MBC) The lowest concentration of an antibiotic that kills colony count
How does the BBB affect ABX single layer of endothelial cells fused by tight junctions to stop molecules
from entering the brain (except small lipophilic ones - like Metronidazole
and Chloramphenicol)
PCN/Vancomycin=low lipid solubility
Infections=inflammed BBB=increased permeability
How does protein binding affect ABX high protein binding=low entry into CSF
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
NURS 5334 Part
Antimicrobials
NURS
1_ Cell
5334
Wall
Part
Antimicrobials
Inhibitors,
1_ Cell Wall
Beta-Lactam
Part
Inhibitors,
1_ CellAntibiotics
Wall
Beta-Lactam
Inhibitors,
& Beta-Lactamase
Antibiotics
Beta-Lactam
& Beta-Lactamase
Inhibitors
AntibioticsStudy
& Beta-Lactamase
Inhibitors
Guide.pdfStudyInhibitors
Guide.pdfStudy Guide.pdf
NURS 5334 Antimicrobials Part 1: Cell
Wall Inhibitors, Beta-Lactam Antibiotics
& Beta-Lactamase Inhibitors Study
Guide
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_
NURS 5334 Antimicrobials
NURS 5334 Part
Antimicrobials
NURS
1_ Cell
5334
Wall
Part
Antimicrobials
Inhibitors,
1_ Cell Wall
Beta-Lactam
Part
Inhibitors,
1_ CellAntibiotics
Wall
Beta-Lactam
Inhibitors,
& Beta-Lactamase
Antibiotics
Beta-Lactam
& Beta-Lactamase
Inhibitors
AntibioticsStudy
& Beta-Lactamase
Inhibitors
Guide.pdfStudyInhibitors
Guide.pdfStudy Guide.pdf
,Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
1 MRSA 2 HIV
3 MSSA 4 VRE
Don't know?
Terms in this set (100)
How do antimicrobials work? ABX: kill pathogens without harming the cell or host
ABX selection requires what identity and susceptibility of pathogen
site of infection
patient factors
safey and efficacy of agent
cost
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
,Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
Empiric Therapy TXT provided prior to bacteria ID
Usualy in acute patients with neutropenia, meningitis, etc
Bacteriostatic inhibits bacterial growth
Bacteriocidal kills bacteria
it is possible for a drug to be both bacteriostatic for one microbe and
bacterocidal for another
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
, Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
Minimum inhibitory concentration (MIC) lowest abx concentration that stops visible bacteria growth after 24 hrs of
incubation
Affects the efficacy of drug
Minimum bactericidal concentration (MBC) The lowest concentration of an antibiotic that kills colony count
How does the BBB affect ABX single layer of endothelial cells fused by tight junctions to stop molecules
from entering the brain (except small lipophilic ones - like Metronidazole
and Chloramphenicol)
PCN/Vancomycin=low lipid solubility
Infections=inflammed BBB=increased permeability
How does protein binding affect ABX high protein binding=low entry into CSF
Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf Nurs 5334 Antimicrobials Part 1_ Cell Wall Inhibitors, Beta Lactam Abx and Inhibitors.pdf
