GENETICS CHAPTER 24 TEST BANK
EXAM QUESTIONS WITH COMPLETE
ANSWERS
Which of the following is TRUE about oncogenes? - Answer-Oncogenes tend to
function in cell growth signal transduction pathways
Choose all that are TRUE statements about tumor-suppressor genes and their roles in
causing cancer. - Answer-Tumor-suppressor genes normally prevent the proliferation of
cancer cells
Tumor-suppressor genes normally halt cell division
The gene p53 is an example of a tumor-suppressor gene
Which of the following is a TRUE statement with regards to the causes of cancer? -
Answer-Of those cancers that are acquired (not inherited), most are the result of
exposure to environmental mutagens that alter the base sequence of the DNA.
Which of the following statements is FALSE about the roles of proto-oncogenes and
oncogenes? - Answer-Oncogenes are normally turned off
Proto-oncogenes are normally turned on/activated in non-dividing cells
Viruses cause cancer by 1 inserting their own version of oncogenes into the genome of
their host cell or 2 altering the regulation of host genes by inserting new promoters
ahead of the host genes. - Answer-True
Which of the following is a type of genetic change that could produce an oncogene? -
Answer-Chromosomal translocation
Gene amplification
Missense mutation
The p53 protein has the function of... - Answer-p53 activates genes that promote
apoptosis, such as caspaces.
Most forms of cancer involve... - Answer-the activation of multiple oncogenes and the
inactivation of multiple tumor-suppressor genes in any number of different orders.
Tumor-suppressor genes promote cancer when... - Answer-their function is inactivated.
With regard to cancer cells, which of the following statements are TRUE? - Answer-To
become cancerous, cells usually accumulate multiple genetic changes that eventually
result in uncontrolled cell growth
Cancer cells are clonal, which means they are derived from a single mutant cell
EXAM QUESTIONS WITH COMPLETE
ANSWERS
Which of the following is TRUE about oncogenes? - Answer-Oncogenes tend to
function in cell growth signal transduction pathways
Choose all that are TRUE statements about tumor-suppressor genes and their roles in
causing cancer. - Answer-Tumor-suppressor genes normally prevent the proliferation of
cancer cells
Tumor-suppressor genes normally halt cell division
The gene p53 is an example of a tumor-suppressor gene
Which of the following is a TRUE statement with regards to the causes of cancer? -
Answer-Of those cancers that are acquired (not inherited), most are the result of
exposure to environmental mutagens that alter the base sequence of the DNA.
Which of the following statements is FALSE about the roles of proto-oncogenes and
oncogenes? - Answer-Oncogenes are normally turned off
Proto-oncogenes are normally turned on/activated in non-dividing cells
Viruses cause cancer by 1 inserting their own version of oncogenes into the genome of
their host cell or 2 altering the regulation of host genes by inserting new promoters
ahead of the host genes. - Answer-True
Which of the following is a type of genetic change that could produce an oncogene? -
Answer-Chromosomal translocation
Gene amplification
Missense mutation
The p53 protein has the function of... - Answer-p53 activates genes that promote
apoptosis, such as caspaces.
Most forms of cancer involve... - Answer-the activation of multiple oncogenes and the
inactivation of multiple tumor-suppressor genes in any number of different orders.
Tumor-suppressor genes promote cancer when... - Answer-their function is inactivated.
With regard to cancer cells, which of the following statements are TRUE? - Answer-To
become cancerous, cells usually accumulate multiple genetic changes that eventually
result in uncontrolled cell growth
Cancer cells are clonal, which means they are derived from a single mutant cell
