- enhance renal blood flow
- block tubuloglomerular feedback (inhibit salt transport into macula densa)
- stimulate renin release
Give this one a try later!
loop diuretics effect on renal hemodynamics
,- DPP4 inhibitiors admin oral, GLP1 agonists injected
- GLP1 injected because its a peptide, which is destroyed in stomach + too large to
cross membranes (unless you have carrier)
Give this one a try later!
PK of incretins
response of the heart to changes in BP, maintains the set point of BP (high or low,
specific to the individual)
Give this one a try later!
baroreceptor reflex
- hypertension
- edema and ascites of hepatic cirrhosis
- chonric congestive heart failure
- hypercalcemia (when combined wwith isotonic saline)
- induce forced diuresis in drug overdose
Give this one a try later!
uses of loop diuretics
inhibits steps in the immune/inflammation pathways to treat ulcerative colitis, and has
modest benefit in Chron's disease
,adverse affects due to sulfapyridine - intestinal nephritis, allergic rxns, hepatitis,
pneumonitis, bone marrow suppression, etc etc
Give this one a try later!
mesalamine (drugs for IBD)
- low glucose
- fasting
- exercise
- somatostatin
- alpha adrenergic agonists
Give this one a try later!
factors that inhibit insulin release
block NK1 receptor for substance P in subthalamic nucleus
used in the delayed phase of chemo nausea/vomiting in patients recieving multiple
cycles of chemo
Give this one a try later!
substance P receptor antagonists as antiemetics
decreased plasma renin activity, Ang I, ANg II, aldosterone
, Give this one a try later!
compensatory effects of renin inhibitors
- RAAS: preferred in young patients
- Ca blockers: preferred in older and black patients
- combination therapy often useful
Give this one a try later!
how to choose what antihypertensive drug to use
drugs that inhibit platelet function
Give this one a try later!
antiplatelet agents
class 1A Na+ ch blocker, preferentially binds to open state of channel.
treats supracentricular and ventricular arrhythmias
may cause lupus-like syndrome
Give this one a try later!
- block tubuloglomerular feedback (inhibit salt transport into macula densa)
- stimulate renin release
Give this one a try later!
loop diuretics effect on renal hemodynamics
,- DPP4 inhibitiors admin oral, GLP1 agonists injected
- GLP1 injected because its a peptide, which is destroyed in stomach + too large to
cross membranes (unless you have carrier)
Give this one a try later!
PK of incretins
response of the heart to changes in BP, maintains the set point of BP (high or low,
specific to the individual)
Give this one a try later!
baroreceptor reflex
- hypertension
- edema and ascites of hepatic cirrhosis
- chonric congestive heart failure
- hypercalcemia (when combined wwith isotonic saline)
- induce forced diuresis in drug overdose
Give this one a try later!
uses of loop diuretics
inhibits steps in the immune/inflammation pathways to treat ulcerative colitis, and has
modest benefit in Chron's disease
,adverse affects due to sulfapyridine - intestinal nephritis, allergic rxns, hepatitis,
pneumonitis, bone marrow suppression, etc etc
Give this one a try later!
mesalamine (drugs for IBD)
- low glucose
- fasting
- exercise
- somatostatin
- alpha adrenergic agonists
Give this one a try later!
factors that inhibit insulin release
block NK1 receptor for substance P in subthalamic nucleus
used in the delayed phase of chemo nausea/vomiting in patients recieving multiple
cycles of chemo
Give this one a try later!
substance P receptor antagonists as antiemetics
decreased plasma renin activity, Ang I, ANg II, aldosterone
, Give this one a try later!
compensatory effects of renin inhibitors
- RAAS: preferred in young patients
- Ca blockers: preferred in older and black patients
- combination therapy often useful
Give this one a try later!
how to choose what antihypertensive drug to use
drugs that inhibit platelet function
Give this one a try later!
antiplatelet agents
class 1A Na+ ch blocker, preferentially binds to open state of channel.
treats supracentricular and ventricular arrhythmias
may cause lupus-like syndrome
Give this one a try later!
